Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Siyuan John Liu"'
Autor:
Sören Müller, Siyuan John Liu, Elizabeth Di Lullo, Martina Malatesta, Alex A Pollen, Tomasz J Nowakowski, Gary Kohanbash, Manish Aghi, Arnold R Kriegstein, Daniel A Lim, Aaron Diaz
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 11, Pp 1-17 (2016)
Abstract Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain tumor. Epidermal growth factor (EGF) and platelet‐derived growth factor (PDGF) receptors are frequently amplified and/or possess gain‐of‐function mut
Externí odkaz:
https://doaj.org/article/f3279c623fe84f949a4613a82e385bad
Autor:
Dae Hwi Park, Sung Jun Hong, Ryan D. Salinas, Siyuan John Liu, Shawn W. Sun, Jacopo Sgualdino, Giuseppe Testa, Martin M. Matzuk, Naoki Iwamori, Daniel A. Lim
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1290-1299 (2014)
The epigenetic mechanisms that enable lifelong neurogenesis from neural stem cells (NSCs) in the adult mammalian brain are poorly understood. Here, we show that JMJD3, a histone H3 lysine 27 (H3K27) demethylase, acts as a critical activator of neurog
Externí odkaz:
https://doaj.org/article/9cb15395f0c748c5839843f52299d7cd
Autor:
Mark Akeson, Sajad Hamid Ahanger, Sung Jun Hong, Aaron Diaz, Daniel He, Daniel A. Lim, Joseph F. Costello, Miao Cui, Miten Jain, Siyuan John Liu, Lin Wang, Parna Saha, Sören Müller, Hugh E. Olson, David Wu
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 13
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 13
Among the large, diverse set of mammalian long noncoding RNAs (lncRNAs), long noncoding primary microRNAs (lnc-pri-miRNAs) are those that host miRNAs. Whether lnc-pri-miRNA loci have important biological function independent of their cognate miRNAs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3e11d6bb09e31f368a2f45da46c475
https://europepmc.org/articles/PMC8020771/
https://europepmc.org/articles/PMC8020771/
Autor:
Tomasz J. Nowakowski, Grace Wilkins, Arnold R. Kriegstein, Diane Jung, Aparna Bhaduri, Siyuan John Liu, Julien Spatazza, Cathryn R. Cadwell, Sören Müller, Eric J. Huang, Madeline G. Andrews, Elizabeth E. Crouch, Martina Malatesta, Daniel A. Lim, Carmen Sandoval Espinosa, David R. Raleigh, Elizabeth Di Lullo, Tomoko Ozawa, Beatriz Alvarado, Dmitry Velmeshev, Aaron Diaz, Mohammed A. Mostajo-Radji
Publikováno v:
Cell stem cell, vol 26, iss 1
Glioblastoma is a devastating form of brain cancer. To identify aspects of tumor heterogeneity that may illuminate drivers of tumor invasion, we created a glioblastoma tumor cell atlas with single-cell transcriptomics of cancer cells mapped onto a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ded707e7c769d41451eadd73fe0abe
https://escholarship.org/uc/item/27j1385w
https://escholarship.org/uc/item/27j1385w
Autor:
Mohammed A. Mostajo-Radji, Alex A. Pollen, Tomasz J. Nowakowski, Xiaohui Wang, Johain Ryad Ounadjela, Beatriz Alvarado, Dmitry Velmeshev, Jay A. A. West, Elizabeth Di Lullo, Maximilian Haeussler, Arnold R. Kriegstein, W. James Kent, Aparna Bhaduri, Siyuan John Liu, Anne A. Leyrat, Carmen Sandoval-Espinosa, Joe Shuga, Daniel A. Lim
Publikováno v:
Science. 358:1318-1323
Building a brain The human brain is built in an inside-out manner as a series of layers. Although progenitor cells spin off new neurons in a seemingly organized fashion, the devil is in the details. Nowakowski et al. analyzed the transcriptomes of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf473b562280751b01e8ad6c96a1aaaa
https://doi.org/10.1126/science.aap8809
https://doi.org/10.1126/science.aap8809
Autor:
Ryan D Salinas, Caitlyn C. Gertz, Sung Jun Hong, Alexander D. Ramos, Daniel A. Lim, Siyuan John Liu, Arnold R. Kriegstein, Tomasz J. Nowakowski, Rebecca E. Andersen, Hosniya Zarabi
Publikováno v:
Cell stem cell, vol 16, iss 4
SummaryWhile thousands of long noncoding RNAs (lncRNAs) have been identified, few lncRNAs that control neural stem cell (NSC) behavior are known. Here, we identify Pinky (Pnky) as a neural-specific lncRNA that regulates neurogenesis from NSCs in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b39ddee49fd5d589bb77876d4c5eba
https://doi.org/10.1016/j.stem.2015.02.007
https://doi.org/10.1016/j.stem.2015.02.007
Autor:
Daniel He, David Wu, Muller, Soren, Lin Wang, Saha, Parna, Ahanger, Sajad Hamid, Siyuan John Liu, Miao Cui, Sung Jun Hong, Jain, Miten, Olson, Hugh E., Akeson, Mark, Costello, Joseph F., Diaz, Aaron, Lim, Daniel A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/30/2021, Vol. 118 Issue 13, p1-12, 12p
Autor:
Siyuan John Liu, Sung Jun Hong, Daniel A. Lim, Naoki Iwamori, Ryan D Salinas, Shawn W. Sun, Dae Hwi Park, Martin M. Matzuk, Giuseppe Testa, Jacopo Sgualdino
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1290-1299 (2014)
Cell reports, vol 8, iss 5
Cell reports, vol 8, iss 5
SummaryThe epigenetic mechanisms that enable lifelong neurogenesis from neural stem cells (NSCs) in the adult mammalian brain are poorly understood. Here, we show that JMJD3, a histone H3 lysine 27 (H3K27) demethylase, acts as a critical activator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432e542f58c09075ba8d77b12fb0575a
http://www.sciencedirect.com/science/article/pii/S2211124714006639
http://www.sciencedirect.com/science/article/pii/S2211124714006639
Autor:
Daniel A. Lim, Benjamin J. Blencowe, Brock A. Harpur, Miao Cui, Siyuan John Liu, Elizabeth Hwang, Rebecca E. Andersen, Sung Jun Hong, Ryan N. Delgado, Justin J. Lim, Alexander D. Ramos
Publikováno v:
Dev Cell
Summary While it is now appreciated that certain long noncoding RNAs (lncRNAs) have important functions in cell biology, relatively few have been shown to regulate development in vivo, particularly with genetic strategies that establish cis versus tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4551d5d64243e289e4db14dde05333
https://doi.org/10.1016/j.devcel.2019.04.032
https://doi.org/10.1016/j.devcel.2019.04.032
Publikováno v:
BioNanoScience. 1:123-127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d9c1ba650604de8e036b8d8c1928633
https://doi.org/10.1007/s12668-011-0018-1
https://doi.org/10.1007/s12668-011-0018-1