Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Siyuan Cheng"'
Autor:
Santhanasabapathy Rajasekaran, Siyuan Cheng, Nithya Gajendran, Sahar Shekoohi, Liudmila Chesnokova, Xiuping Yu, Stephan N. Witt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The Parkinson’s disease protein, alpha-synuclein (α-syn/SNCA), is highly expressed in neurons and melanomas. The goal of this study was to reveal the mechanism(s) of α-syn’s involvement in melanoma pathogenesis. To decipher the genes a
Externí odkaz:
https://doaj.org/article/e0b3c8a4780b4b5f8952b79fd5412b48
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background The stress hyperglycemia ratio (SHR) was developed to mitigate the influence of long-term chronic glycemic factors on stress hyperglycemia levels, which are associated with adverse clinical events, particularly cardiovascular even
Externí odkaz:
https://doaj.org/article/695aec83e48946e88eae9314a2d1b6f4
Autor:
Zifan Chen, Yang Chen, Yu Sun, Lei Tang, Li Zhang, Yajie Hu, Meng He, Zhiwei Li, Siyuan Cheng, Jiajia Yuan, Zhenghang Wang, Yakun Wang, Jie Zhao, Jifang Gong, Liying Zhao, Baoshan Cao, Guoxin Li, Xiaotian Zhang, Bin Dong, Lin Shen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract The sole use of single modality data often fails to capture the complex heterogeneity among patients, including the variability in resistance to anti-HER2 therapy and outcomes of combined treatment regimens, for the treatment of HER2-positiv
Externí odkaz:
https://doaj.org/article/062220a2398042a6b940e9ea3599d1a0
Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysis
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Recent advancements in single-cell RNA sequencing (scRNAseq) have facilitated the discovery of previously unrecognized subtypes within prostate cancer (PCa), offering new insights into cancer heterogeneity and progression. In this study, we
Externí odkaz:
https://doaj.org/article/93af65cbcce64ac1a1e9f0bb040c8afc
Publikováno v:
APL Materials, Vol 12, Iss 8, Pp 081116-081116-13 (2024)
Elastocaloric cooling technology has the prospect of becoming a commercialized green alternative to current vapor-compression technology, and the systematic characterization of the elastocaloric effect and microstructure has become increasingly signi
Externí odkaz:
https://doaj.org/article/2bca28eae1f247fc8cd2a3768d28dede
Publikováno v:
eLife, Vol 13 (2024)
Vascular smooth muscle cells (VSMCs) envelop vertebrate brain arteries and play a crucial role in regulating cerebral blood flow and neurovascular coupling. The dedifferentiation of VSMCs is implicated in cerebrovascular disease and neurodegeneration
Externí odkaz:
https://doaj.org/article/bcca6ef413674024822362f554fd1b5d
Publikováno v:
Journal of Engineering and Applied Science, Vol 71, Iss 1, Pp 1-21 (2024)
Abstract The design process for pile foundations necessitates meticulous deliberation of the calculation pertaining to the bearing capacity of the piles. The primary objective of this work was to investigate the potential use of Coot bird optimizatio
Externí odkaz:
https://doaj.org/article/d77c41c6d4be4a53828c34ff3e74e5dd
Publikováno v:
AIP Advances, Vol 14, Iss 5, Pp 055123-055123-14 (2024)
Comprehensive characterizations of the superelastic and elastocaloric effects of NiTi and NiTi-based shape memory alloys (SMA) in the operation temperature region are highly desirable for using them in elastocaloric coolers with a large temperature l
Externí odkaz:
https://doaj.org/article/37f9a26c6d8b4d038cd7ec2dfbd7b43e
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionAn increasing body of research has demonstrated a correlation between pollutants from the environment and the development of cardiovascular diseases (CVD). However, the impact of volatile organic chemicals (VOC) on CVD remains unknown and
Externí odkaz:
https://doaj.org/article/c1102bec0f6a406ab6d742160289753f
Autor:
Lin Li, Siyuan Cheng, Yunshin Yeh, Yingli Shi, Nikayla Henderson, David Price, Xin Gu, Xiuping Yu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundNeuroendocrine prostate cancer (NEPCa) is the most aggressive type of prostate cancer (PCa). However, energy metabolism, one of the hallmarks of cancer, in NEPCa has not been well studied. Pyruvate kinase M (PKM), which catalyzes the final
Externí odkaz:
https://doaj.org/article/ba1a2f366d1546e3919fc2496c548a8c