Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Siyu, Shen"'
Autor:
Ke Lu, Ming Zhang, Hongyu Qin, Siyu Shen, Haiqing Song, Hua Jiang, Chunxiang Zhang, Guozhi Xiao, Liping Tong, Qing Jiang, Di Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2977-2991 (2024)
Cyclin D1 has been recognized as an oncogene due to its abnormal upregulation in different types of cancers. Here, we demonstrated that cyclin D1 is SUMOylated, and we identified Itch as a specific E3 ligase recognizing SUMOylated cyclin D1 and media
Externí odkaz:
https://doaj.org/article/cbcacfc28a4a4fb8b240e5790891f587
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113749- (2024)
Summary: Aberrant long interspersed element 1 (LINE-1 or L1) activity can cause insertional mutagenesis and chromosomal rearrangements and has been detected in several types of cancers. Here, we show that neddylation, a post-translational modificatio
Externí odkaz:
https://doaj.org/article/f25bb011dbc44722ae9444f42d2b5f1b
Publikováno v:
Bioactive Materials, Vol 24, Iss , Pp 477-496 (2023)
Large bone defects resulting from fractures and disease are a major clinical challenge, being often unable to heal spontaneously by the body's repair mechanisms. Lines of evidence have shown that hypoxia-induced overproduction of ROS in bone defect r
Externí odkaz:
https://doaj.org/article/68941bb620844af7a421d97583f248b7
Autor:
Qiang Wen, ShouJun Wang, Lili Hong, Siyu Shen, Yibo He, Xianfu Sheng, Xiaofen Zhuang, Shiliang Chen, Ying Wang, Haifeng Zhuang
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Background Recently, many studies have been conducted to examine immune response modification at epigenetic level, but the candidate effect of RNA 5‐methylcytosine (m5C) modification on tumor microenvironment (TME) of acute myeloid leukemi
Externí odkaz:
https://doaj.org/article/87510ed287034e1abd4cf49de6d6999a
Autor:
Mingli Chen, Siyu Shen, Zhiyuan Li, Huashun Wang, Jin Wang, Guangyu Yang, Wenwu Yang, Lele Deng, Daping Gong, Jianduo Zhang
Publikováno v:
Agronomy, Vol 14, Iss 2, p 321 (2024)
2-acetyl-1-pyrroline (2AP) is a highly effective volatile compound that gives fragrance to numerous plant species and food. Mutation(s) in the betaine aldehyde dehydrogenase 2 (BADH2) gene results in the accumulation of 2AP. However, the function of
Externí odkaz:
https://doaj.org/article/562f738864504276a3a299cf00437d4e
Autor:
Lei Zhang, Ziguo Qin, Han Sun, Xiang Chen, Jian Dong, Siyu Shen, Liming Zheng, Ning Gu, Qing Jiang
Publikováno v:
Bioactive Materials, Vol 18, Iss , Pp 1-14 (2022)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and destruction of cartilage, promoted by sustained inflammation. However, current treatments remain unsatisfactory due to lacking of selective and effective strat
Externí odkaz:
https://doaj.org/article/14c73f576c074b7b9e30a4d952db7d2e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Reconstruction of cranial bone defects is one of the most challenging problems in reconstructive surgery, and several biological tissue engineering methods have been used to promote bone repair, such as genetic engineering of bone marrow
Externí odkaz:
https://doaj.org/article/287b60840a1d4ca2928132bfdf4aba0c
Autor:
Tianshu Shi, Yong Shi, Hongliang Gao, Yuze Ma, Qianjin Wang, Siyu Shen, Xiaoyan Shao, Wang Gong, Xiang Chen, Jian Qin, Jing Wu, Qing Jiang, Bin Xue
Publikováno v:
Journal of Orthopaedic Translation, Vol 35, Iss , Pp 1-12 (2022)
Background: Reduced serum estrogen levels in postmenopausal patients not only aggravate bone loss but also impact myokine secretion. Emerging evidence has revealed the importance of myokines in bone metabolism, and exercise can interfere with the sec
Externí odkaz:
https://doaj.org/article/d2e81c28ab1d4b6ab5f45c8168e991ca
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Introduction Chronic periodontitis (CP) is an inflammatory periodontal disease with high incidence and complex pathology. This research is aimed to investigate the function of exosomal miR‐205‐5p (Exo‐miR‐205‐5p) in CP and the unde
Externí odkaz:
https://doaj.org/article/08bcec89227e4fccb9b47a0b71c3c19e
Autor:
Lei Zhang, Zhiguo Qin, Han Sun, Xiang Chen, Jian Dong, Siyu Shen, Liming Zheng, Ning Gu, Qing Jiang
Publikováno v:
Bioactive Materials, Vol 19, Iss , Pp 486- (2023)
Externí odkaz:
https://doaj.org/article/5bb7323dcb91409cb2477b7543920d87