Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Siyouneh Baghdasarian"'
Autor:
Michael Shum, Mayuko Segawa, Raffi Gharakhanian, Ana Viñuela, Matthew Wortham, Siyouneh Baghdasarian, Dane M. Wolf, Samuel B. Sereda, Laura Nocito, Linsey Stiles, Zhiqiang Zhou, Vincent Gutierrez, Maike Sander, Orian S. Shirihai, Marc Liesa
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101403- (2022)
Objective: The contribution of beta-cell dysfunction to type 2 diabetes (T2D) is not restricted to insulinopenia in the late stages of the disease. Elevated fasting insulinemia in normoglycemic humans is a major factor predicting the onset of insulin
Externí odkaz:
https://doaj.org/article/9dc2c70f85334be6a42fd766bfb0b160
Autor:
Rebeca Acín-Perez, Anton Petcherski, Michaela Veliova, Ilan Y. Benador, Essam A. Assali, Georgia Colleluori, Saverio Cinti, Alexandra J. Brownstein, Siyouneh Baghdasarian, Masha J. Livhits, Michael W. Yeh, Karthickeyan Chella Krishnan, Laurent Vergnes, Nathan C. Winn, Jaume Padilla, Marc Liesa, Harold S. Sacks, Orian S. Shirihai
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102087- (2021)
Beige adipocyte mitochondria contribute to thermogenesis by uncoupling and by ATP-consuming futile cycles. Since uncoupling may inhibit ATP synthesis, it is expected that expenditure through ATP synthesis is segregated to a disparate population of mi
Externí odkaz:
https://doaj.org/article/4b8e9dfe1be44446bb4a1b85629f27e1
Autor:
Hsuan-Ping Lin, Siyouneh Baghdasarian, Martha R. Singer, Melanie M. Mott, M. Loring Bradlee, Richard T. Pickering, Lynn L. Moore
Publikováno v:
Nutrients, Vol 10, Iss 6, p 770 (2018)
Previous recommendations to limit dietary cholesterol intake have been eliminated for most adults. Questions remain about whether dietary cholesterol has adverse cardiovascular effects among individuals with impaired fasting glucose or diabetes (IFG/
Externí odkaz:
https://doaj.org/article/155e432e9fe54ab3ac36c67665077aa4
Autor:
Siyouneh Baghdasarian, Hsuan-Ping Lin, Richard T. Pickering, Melanie M. Mott, Martha R. Singer, M. Loring Bradlee, Lynn L. Moore
Publikováno v:
Nutrients, Vol 10, Iss 6, p 665 (2018)
Identification of diet and lifestyle risk factors for prevention of type 2 diabetes mellitus (T2DM) is of great importance. The specific role of dietary cholesterol (DC) in T2DM risk is unclear. This study uses data from 2192 Framingham Offspring Stu
Externí odkaz:
https://doaj.org/article/3c08373c13bf4bdb94198dba851c7622
Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA
Autor:
Jennifer Ngo, Dong Wook Choi, Illana A Stanley, Linsey Stiles, Anthony J A Molina, Pei‐Hsuan Chen, Ana Lako, Isabelle Chiao Han Sung, Rishov Goswami, Min‐young Kim, Nathanael Miller, Siyouneh Baghdasarian, Doyeon Kim‐Vasquez, Anthony E Jones, Brett Roach, Vincent Gutierrez, Karel Erion, Ajit S Divakaruni, Marc Liesa, Nika N Danial, Orian S Shirihai
Publikováno v:
The EMBO Journal. 42
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies
Autor:
Rebeca Acin‐Perez, Cristiane Benincá, Lucia Fernandez del Rio, Cynthia Shu, Siyouneh Baghdasarian, Vanessa Zanette, Christoph Gerle, Chimari Jiko, Ramzi Khairallah, Shaharyar Khan, David Rincon Fernandez Pacheco, Byourak Shabane, Karel Erion, Ruchi Masand, Sundeep Dugar, Cristina Ghenoiu, George Schreiner, Linsey Stiles, Marc Liesa, Orian S Shirihai
Publikováno v:
The EMBO Journal. 42
Autor:
Linsey Stiles, Maike Sander, Samuel B. Sereda, Zhiqiang Zhou, Ana Viñuela, Siyouneh Baghdasarian, Vincent Gutierrez, Mayuko Segawa, Laura Nocito, Matthew Wortham, Raffi Gharakhanian, Marc Liesa, Michael Shum, Orian S. Shirihai, Dane M. Wolf
Publikováno v:
Molecular Metabolism, Vol 55, Iss, Pp 101403-(2022)
Molecular Metabolism
Molecular Metabolism
Objective The contribution of beta-cell dysfunction to type 2 diabetes (T2D) is not restricted to insulinopenia in the late stages of the disease. Elevated fasting insulinemia in normoglycemic humans is a major factor predicting the onset of insulin
Autor:
Joshua J. Wilhelm, Jakob D. Wikstrom, Eleni Ritou, Melena D. Bellin, Orian S. Shirihai, Richard G. Kibbey, Zachary Swanson, Linsey Stiles, Siyouneh Baghdasarian, Karel A. Erion, Nour Alsabeeh, Jin Li, Samuel B. Sereda, Marc Liesa, Evan P. Taddeo, Muhamad Abdulla
Publikováno v:
Diabetes
Fasting hyperinsulinemia precedes the development of type 2 diabetes. However, it is unclear whether fasting insulin hypersecretion is a primary driver of insulin resistance or a consequence of the progressive increase in fasting glycemia induced by