Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Siyi Zheng"'
Autor:
Cailin Wang, Xiufeng Wang, Shangqi Sun, Yanmin Chang, Piaopiao Lian, Hongxiu Guo, Siyi Zheng, Rong Ma, Gang Li
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background The accumulation of senescent microglia has been highlighted as a critical contributor to the progression of tauopathies. Irisin, a muscle-derived hormone produced by the proteolytic cleavage of Fibronectin-domain III containing 5
Externí odkaz:
https://doaj.org/article/ed3f7a363a1d43e6a73262dc359e05f3
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Alzheimer’s disease (AD) stands as a formidable neurodegenerative ailment and a prominent contributor to dementia. The scarcity of available therapies for AD accentuates the exigency for innovative treatment modalities. Psilocybin, a psychoactive a
Externí odkaz:
https://doaj.org/article/6974a3b5cd59498ca7bf13a9f5727c3d
Autor:
Hui Han, Yucong Sun, Wei Wei, Zixin Huang, Maosheng Cheng, Hongshen Qiu, Juan Wang, Siyi Zheng, Lianlian Liu, Qiang Zhang, Canfeng Zhang, Jieyi Ma, Siyao Guo, Zhaoyu Wang, Zhenpeng Li, Xu Jiang, Shuibin Lin, Qianwen Liu, Shuishen Zhang
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109327- (2024)
Summary: Emerging studies have demonstrated the link between RNA modifications and various cancers, while the predictive value and functional mechanisms of RNA modification-related genes (RMGs) in esophageal squamous cell carcinoma (ESCC) remain uncl
Externí odkaz:
https://doaj.org/article/d26ae0dca59d488eb95f86eb65e7e171
Autor:
Yanmin Chang, Cailin Wang, Jiahui Zhu, Siyi Zheng, Shangqi Sun, Yanqing Wu, Xingjun Jiang, Lulu Li, Rong Ma, Gang Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Diabetes is associated with an increased risk of cognitive decline and dementia. These diseases are linked with mitochondrial dysfunction, most likely as a consequence of excessive formation of mitochondria-associated membranes (M
Externí odkaz:
https://doaj.org/article/6a3f34e842954b2196905366f244745c
Autor:
Wei Wei, Shuishen Zhang, Hui Han, Xiaochen Wang, Siyi Zheng, Zhaoyu Wang, Chunlong Yang, Lu Wang, Jieyi Ma, Siyao Guo, Juan Wang, Lianlian Liu, Junho Choe, Shuibin Lin
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112810- (2023)
Summary: Aberrant RNA modifications are frequently associated with cancers, while the underlying mechanisms and clinical significance remain poorly understood. Here, we find that the ac4C RNA acetyltransferase NAT10 is significantly upregulated in es
Externí odkaz:
https://doaj.org/article/a3f40575b2bb45beac269ae22cbdc878
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 4, Pp 385-397 (2022)
Growing evidence supports that cancer progression is closely associated with the tumor microenvironment and immune evasion. Importantly, recent studies have revealed the crucial roles of epigenetic regulators in shaping the tumor microenvironment and
Externí odkaz:
https://doaj.org/article/f754e06c35f44d79b1bffa6440b75937
Autor:
Hui Han, Chunlong Yang, Jieyi Ma, Shuishen Zhang, Siyi Zheng, Rongsong Ling, Kaiyu Sun, Siyao Guo, Boxuan Huang, Yu Liang, Lu Wang, Shuang Chen, Zhaoyu Wang, Wei Wei, Ying Huang, Hao Peng, Yi-Zhou Jiang, Junho Choe, Shuibin Lin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Deregulation of METTL1-mediated N7- methylguanosine tRNA modification can promote oncogenesis. Here, the authors report that this modification regulates the translation of proteins in both the mTOR and negative regulators of autophagy pathways, resul
Externí odkaz:
https://doaj.org/article/f2ee912cfd1b4d88a341d2e5aa7507df
Autor:
Siyi Zheng, Qiongying Shen, Zhengyi Lyu, Shuxin Tian, Xiaoxiao Huang, Yiyue Liu, Xiaoshuai Yu, Wei Pan, Na Nie, Yi Liang, Jianqiao Fang
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0291536 (2023)
BackgroundLow back pain is a common complaint among adults, and moxibustion and acupuncture are commonly used treatments. In traditional theory, Weizhong (BL40) is a popular acupoint, as supported by the saying "Yao Bei Wei Zhong Qiu." However, the d
Externí odkaz:
https://doaj.org/article/b201999bdafc41b78f567441a1f81b0a
Autor:
Hui Han, Chunlong Yang, Shuishen Zhang, Maosheng Cheng, Siyao Guo, Yan Zhu, Jieyi Ma, Yu Liang, Lu Wang, Siyi Zheng, Zhaoyu Wang, Demeng Chen, Yi-Zhou Jiang, Shuibin Lin
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 333-346 (2021)
Esophageal cancer is a lethal malignancy with a high mortality rate, while the molecular mechanisms underlying esophageal cancer pathogenesis are still poorly understood. Here, we found that the N6-methyladenosine (m6A) methyltransferase-like 3 (METT
Externí odkaz:
https://doaj.org/article/f647afb633ac4c929f84408825892366
Publikováno v:
Cancer Biology & Medicine. Apr2022, Vol. 19 Issue 4, p385-397. 13p.