Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Siyaram Pandey"'
Autor:
Krithika Muthukumaran, Samantha Leahy, Kate Harrison, Marianna Sikorska, Jagdeep K. Sandhu, Jerome Cohen, Corrine Keshan, Daniel Lopatin, Harvey Miller, Henryk Borowy-Borowski, Patricia Lanthier, Shelly Weinstock, Siyaram Pandey
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/fea6e84fba8a4184b91285283bd97d88
Autor:
Christopher Nguyen, Kiruthika Baskaran, Alaina Pupulin, Ivan Ruvinov, Ola Zaitoon, Sahibjot Grewal, Benjamin Scaria, Ali Mehaidli, Caleb Vegh, Siyaram Pandey
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Current therapeutic approaches to treat metastatic breast cancer, although effective, have shown many inadvertent side effects such as genotoxicity due to a lack of selectivity. Thus, these treatment plans are not suitable for lon
Externí odkaz:
https://doaj.org/article/d78169cc716349a6958802cea839ba9d
Publikováno v:
Integrative Cancer Therapies, Vol 20 (2021)
Melanoma is the deadliest form of skin cancer in the world with a growing incidence in North America. Contemporary treatments for melanoma include surgical resection, chemotherapy, and radiotherapy. However, apart from resection in early melanoma, th
Externí odkaz:
https://doaj.org/article/a05cee3754194b429606a2c6ae1c330c
Autor:
Ivan Ruvinov BSc, Christopher Nguyen BSc, Benjamin Scaria BSc, Caleb Vegh BSc, Ola Zaitoon MMB, Kiruthika Baskaran BSc, Ali Mehaidli BSc, Malika Nunes MSc, Siyaram Pandey PhD
Publikováno v:
Integrative Cancer Therapies, Vol 18 (2019)
Current chemotherapeutics for metastatic colorectal cancers have limited success and are extremely toxic due to nonselective targeting. Some natural extracts have been traditionally taken and have shown anticancer activity. These extracts have multip
Externí odkaz:
https://doaj.org/article/accdf523c7784945bd901e897647629e
Autor:
Christopher Pignanelli, Dennis Ma, Megan Noel, Jesse Ropat, Fadi Mansour, Colin Curran, Simon Pupulin, Kristen Larocque, Jianzhang Wu, Guang Liang, Yi Wang, Siyaram Pandey
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-25 (2017)
Abstract Recently, research has focused on targeting the oxidative and metabolic vulnerabilities in cancer cells. Natural compounds like curcumin that target such susceptibilities have failed further clinical advancements due to the poor stability an
Externí odkaz:
https://doaj.org/article/541280dca3a14ddc9144ea845137126b
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 764 (2021)
The world continues a desperate search for therapies that could bring hope and relief to millions suffering from progressive neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s (PD). With oxidative stress thought to be a core stre
Externí odkaz:
https://doaj.org/article/2dfc511cdd3b45a087e73fbb1dd3297d
Autor:
Caleb Vegh, Darcy Wear, Iva Okaj, Rachel Huggard, Lauren Culmone, Sezen Eren, Jerome Cohen, Arun K. Rishi, Siyaram Pandey
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 563 (2021)
Parkinson’s disease (PD) is characterized by progressive neurodegeneration in the substantia nigra (SN) region resulting in loss of movement coordination. Current therapies only provide symptomatic relief, and there is no agent to halt the progress
Externí odkaz:
https://doaj.org/article/382b54fa7c3c48528f27a4c53b5f6c71
Autor:
Daniel Tarade, Dennis Ma, Christopher Pignanelli, Fadi Mansour, Daniel Simard, Sean van den Berg, James Gauld, James McNulty, Siyaram Pandey
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0171806 (2017)
The cis-stilbene, combretastatin A4 (CA4), is a potent microtubule targeting and vascular damaging agent. Despite promising results at the pre-clinical level and extensive clinical evaluation, CA4 has yet to be approved for therapeutic use. One imped
Externí odkaz:
https://doaj.org/article/b7f5c72fc58549d5809c36b4f4e08240
Autor:
Krishan Parashar, Siddhartha Sood, Ali Mehaidli, Colin Curran, Caleb Vegh, Christopher Nguyen, Christopher Pignanelli, Jianzhang Wu, Guang Liang, Yi Wang, Siyaram Pandey
Publikováno v:
Molecules, Vol 24, Iss 13, p 2483 (2019)
Melanoma is the leading cause of skin-cancer related deaths in North America. Metastatic melanoma is difficult to treat and chemotherapies have limited success. Furthermore, chemotherapies lead to toxic side effects due to nonselective targeting of n
Externí odkaz:
https://doaj.org/article/773ac086c90f44359ed3a981796f1394
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)
Purpose: Natural products have been a great source of medications used in conventional medicines for the treatment of various diseases; more importantly, they have played a significant role in the development of anti-cancer drugs for a number of deca
Externí odkaz:
https://doaj.org/article/fe8d4e3ca2d2453691df458610238071