Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sixun CHEN"'
Publikováno v:
BMC Biotechnology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The in-vitro scratch assay is a useful method in wound healing research to assess cell migration. In this assay, a scratch is created in a confluent cell layer by mechanically removing cells through manual scraping with a sharp-ed
Externí odkaz:
https://doaj.org/article/bf46f2b1af9d45dcb7884ec08a356734
Autor:
Sixun Chen, Ahmad Amirul Bin Abdul Rahim, Who-Whong Wang, Rachael Cheong, Akshaya V. Prabhu, Jerome Zu Yao Tan, May Win Naing, Han Chong Toh, Dan Liu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The ex-vivo expansion of antigen-specific T-cells for adoptive T-cell immunotherapy requires active interaction between T-cells and antigen-presenting cells therefore culture density and environment become important variables to control. Mai
Externí odkaz:
https://doaj.org/article/7e78bacd297a42229e6b0dfbbe65eb8f
Publikováno v:
You-qi chuyun, Vol 40, Iss 6, Pp 643-650 (2021)
According to the concept of intelligent pipeline network and the current status of pipeline enterprises, it was put forward that Digital Twin was the basic method and theoretical basis to realize the intelligent pipeline network. Thereby, based on th
Externí odkaz:
https://doaj.org/article/b1f212518ea74410b5717f2d732461ec
Autor:
Weichao Zhai, Jerome Tan, Tobias Russell, Sixun Chen, Dennis McGonagle, May Win Naing, Derrick Yong, Elena Jones
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Human mesenchymal stromal cells (hMSCs) have demonstrated, in various preclinical settings, consistent ability in promoting tissue healing and improving outcomes in animal disease models. However, translation from the preclinical model into
Externí odkaz:
https://doaj.org/article/b7f21e41506c4da7b9df7d2a24745571
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Sterile fluid transfer between vessels is a key step in cell therapy manufacturing and requires specialised devices to maintain sterility of both vessels before, during and after the transfer. This review introduces two main types of devices for ster
Externí odkaz:
https://doaj.org/article/3a15bd4c69b04774bc19959e4980e159
Autor:
Derrick Yong, Ahmad Amirul Abdul Rahim, Chaw Su Thwin, Sixun Chen, Weichao Zhai, May Win Naing
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226757 (2019)
Patient-specific therapies require that cells be manufactured in multiple batches of small volumes, making it a challenge for conventional modes of quality control. The added complexity of inherent variability (even within batches) necessitates const
Externí odkaz:
https://doaj.org/article/40640e10771a474ba06826238d1ef568
Autor:
Derrick Yong, Elena Jones, Weichao Zhai, Tobias Russell, Sixun Chen, May Win Naing, Jerome Tan, Dennis McGonagle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Human mesenchymal stromal cells (hMSCs) have demonstrated, in various preclinical settings, consistent ability in promoting tissue healing and improving outcomes in animal disease models. However, translation from the preclinical model into clinical
Publikováno v:
Biotechnology and Bioengineering. 118:542-554
Spheroid culture provides cells with a three-dimensional environment that can better mimic physiological conditions compared to monolayer culture. Technologies involved in the generation of cell spheroids are continuously being innovated to produce s
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11929, p 11929 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 11929, p 11929 (2021)
Cell-derived matrices (CDM) are the decellularised extracellular matrices (ECM) of tissues obtained by the laboratory culture process. CDM is developed to mimic, to a certain extent, the properties of the needed natural tissue and thus to obviate the
Autor:
Stuart L. Schreiber, Volker Badock, Anneke Kramm, Vasanthi S. Viswanathan, Roland Neuhaus, Besnik Bajrami, Dieter Moosmayer, Luke L. Cai, Claire Montagnon, Matthew J. Ryan, Kiel Lazarski, Michael Niehues, Laura Furst, Katja Zimmermann, Ashley Eheim, Sixun Chen, Paul A. Clemons, Sven Christian, Stefan Gradl, A. Hilpmann, John K. Eaton, Richard A. Ruberto, Roman C. Hillig
Publikováno v:
Nat Chem Biol
We recently described glutathione peroxidase 4 (GPX4) as a promising target for killing therapy-resistant cancer cells via ferroptosis. The onset of therapy resistance by multiple types of treatment results in a stable cell state marked by high level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9dba21b4ff5e31f86e9c6937b70befa
https://europepmc.org/articles/PMC7251976/
https://europepmc.org/articles/PMC7251976/