Zobrazeno 1 - 10
of 700
pro vyhledávání: '"Sivelestat"'
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background We aimed to assess the efficacy of the neutrophil elastase inhibitor, sivelestat, in the treatment of sepsis-induced acute respiratory distress syndrome (ARDS) and septic cardiomyopathy (SCM). Methods Between January 2019 and Dece
Externí odkaz:
https://doaj.org/article/40123635b9814f3ca74d6015074dc7c3
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Objective This comparative analysis aimed to investigate the efficacy of Sivelestat Sodium Hydrate (SSH) combined with Ulinastatin (UTI) in the treatment of sepsis with acute respiratory distress syndrome (ARDS). Methods A control group and
Externí odkaz:
https://doaj.org/article/8ce6b3819d8f4055ad92d1f6ae981e4c
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 2701-2709 (2024)
Wang Yi,1,2 Weikai Wang,3 Hua Zhang,2 Ying Wang,2 Yong Zhou,2 Zhangyan Guo,2 Jingmei Li,2 Le Ma,2 Dan Yao,2 Taining Zhang,3 Yanqiang Du,2 Li Liu1 1Department of Neonatology, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi,
Externí odkaz:
https://doaj.org/article/5ff2d489899e4e0aa17ab217cc057852
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Neutrophil elastase (NE) is a proteolytic enzyme released extracellular during the formation of neutrophil extracellular traps (NETs) through degranulation. In addition to participating in the body's inflammatory response, NE also plays an i
Externí odkaz:
https://doaj.org/article/3df990ee4abf48a9aebdfa5a5c2c0437
Autor:
Ruiying Wang, Junping Yin, Jian Li, Xueli Bai, Hu Liu, Mengyu Cheng, Lei Wang, Yuan Chen, Shuang Wei, Xiansheng Liu
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36337- (2024)
Background: Sivelestat, a neutrophil elastase inhibitor, is postulated to mitigate acute lung injury in patients following emergency surgery. However, its efficacy in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS
Externí odkaz:
https://doaj.org/article/2d61723edac64208b8bd7a5a82a00daa
Autor:
Tang YX, Fan ZW, Li J, Pan HD, Su WX, Matniyaz Y, Zhang HT, Luo YX, Lv ZK, Wang WZ, Gao YX, Pan T, Xu WZ, Wang DJ
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 591-601 (2024)
Yu-Xian Tang,1,* Zhi-Wei Fan,1,* Jing Li,2,* Hao-Dong Pan,3 Wen-Xin Su,1 Yusanjan Matniyaz,2 Hai-Tao Zhang,4 Yuan-Xi Luo,4 Zhi-Kang Lv,2 Wen-Zhe Wang,2 Ya-Xuan Gao,2 Tuo Pan,2,4 Wan-Zi Xu,1,2 Dong-Jin Wang1– 4 1Department of Cardiac Sur
Externí odkaz:
https://doaj.org/article/db8377d7f7834939af9ebf3fca6978f1
Autor:
Wei Zhu, Yingwei Ou, Chunnian Wang, Rongcheng An, Junmei Lai, Ye Shen, Xiangming Ye, Haochu Wang
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29366- (2024)
Background: Sivelestat, a selective inhibitor of neutrophil elastase (NE), can mitigate sepsis-related acute lung injury. However, the role of sivelestat in inhibiting oxidative stress and attenuating sepsis-related acute kidney injury (AKI) remains
Externí odkaz:
https://doaj.org/article/2e54cf0ec58f44ee82d35bf7f9eade7f
Publikováno v:
Intensive Care Research, Vol 3, Iss 2, Pp 140-149 (2023)
Abstract Background The efficacy of neutrophil elastase inhibitor sivelestat in the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remains controversial. A systematic review and meta-analysis were performed in acc
Externí odkaz:
https://doaj.org/article/60ccd226c79f46909a34dc8b5408ba10
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 4, Pp 355-366 (2023)
Neutrophil elastase (NE), a major protease in the primary granules of neutrophils, is involved in microbicidal activity. NE is an important factor promoting inflammation, has bactericidal effects, and shortens the inflammatory process. NE also regula
Externí odkaz:
https://doaj.org/article/609762a6959e4d65a122bc97cb025f50
Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 707-721 (2023)
Chun-Lian Wang,1 Yan Wang,2 Qi-Lan Jiang,3 Yang Zeng,4 Qing-Ping Yao,5 Xing Liu,6 Tao Li,7 Jun Jiang1 1Department of General Surgery (Thyroid Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, People’s Republic of China; 2De
Externí odkaz:
https://doaj.org/article/61d7e8fd3a2c442d9ff78f76fe7aed0d