Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sivasithambaram Niranjali Devaraj"'
Autor:
Venugopal Vinod Prabhu, Perumal Elangovan, Sivasithambaram Niranjali Devaraj, Kunnathur Murugesan Sakthivel
Publikováno v:
Biotechnology Reports, Vol 29, Iss , Pp e00594- (2021)
Lung cancer is the leading cause of cancer deaths globally. The objective of this study was to investigate the effect of 1,2-diazole (pyrazole) as an anti-cancer drug on human non-small cell lung carcinoma A549 cells. We attempt to examine the expres
Externí odkaz:
https://doaj.org/article/433e3f89158f45b3b2d1eb930a8015f5
Autor:
Venugopal Vinod Prabhu, Perumal Elangovan, Sivasithambaram Niranjali Devaraj, Kunnathur Murugesan Sakthivel
Publikováno v:
Biotechnology Reports
Biotechnology Reports, Vol 29, Iss, Pp e00594-(2021)
Biotechnology Reports, Vol 29, Iss, Pp e00594-(2021)
Graphical abstract
Highlights • 1,2-Diazole suppresses TNF-α induced MMP-2 expression. • 1,2-Diazole abrogate NF-κB activation and regulate cytokines. • It exhibits potent in vitro anticancer effect against A549 cells.
Lung cancer i
Highlights • 1,2-Diazole suppresses TNF-α induced MMP-2 expression. • 1,2-Diazole abrogate NF-κB activation and regulate cytokines. • It exhibits potent in vitro anticancer effect against A549 cells.
Lung cancer i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539dcdcd1a63d543003684ada14921a9
https://pubmed.ncbi.nlm.nih.gov/33598414
https://pubmed.ncbi.nlm.nih.gov/33598414
Publikováno v:
Biochimie. 148:63-71
Notch signaling plays a pivotal role in homeostasis and cardiovascular development. The role of notch signaling in atherosclerosis cannot be complete without analysing the key role of notch in macrophages, which trigger the inflammatory response and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473fe3945a546577ae6c4419ce05b5f
https://doi.org/10.1016/j.biochi.2018.02.011
https://doi.org/10.1016/j.biochi.2018.02.011
Publikováno v:
Journal of biochemical and molecular toxicologyREFERENCES. 34(2)
M1 macrophages serve one edge as proinflammatory and M2 macrophages serve the other edge as an anti-inflammatory macrophage. It appears that a related "switch" in macrophage morphology may also happen in the course of atherosclerosis, which has not y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40e05fac5eab2608dbbd84d9ff570a3
https://pubmed.ncbi.nlm.nih.gov/31729780
https://pubmed.ncbi.nlm.nih.gov/31729780
Autor:
Perumal Elangovan, Venugopal Vinod Prabhu, Sivasithambaram Niranjali Devaraj, Kunnathur Murugesan Sakthivel
Publikováno v:
Gene. 679
Lung cancer is the leading cause of cancer deaths worldwide and non-small cell lung carcinoma (NSCLC), a heterogeneous class of tumors, represents approximately 85% of all new lung cancer diagnosis. Conventional treatment options have limited efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1469a7beeccf97b5e7d3a502f85a4edb
https://pubmed.ncbi.nlm.nih.gov/30218747
https://pubmed.ncbi.nlm.nih.gov/30218747
Autor:
Ramadass Nandha Kumar, Sivasithambaram Niranjali Devaraj, Kasinathan Nirmal Kumar, Kombiyil Salini
Publikováno v:
Biomedicine & Preventive Nutrition. 4:277-290
Chemoprevention plays pivotal role in the prevention of human cancers. Morin, a bioflavonoid, has been known for its chemopreventive activities against various cancers and also in recent years, numerous investigations have shown that flavonol contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::349df20f47dfe87ccf8086d314f902b3
https://doi.org/10.1016/j.bionut.2014.01.002
https://doi.org/10.1016/j.bionut.2014.01.002
Autor:
Sivasithambaram Niranjali Devaraj, Ramakrishnan Padmini, Chandragiri Janakiraman Thirupurasundari
Publikováno v:
Chemico-Biological Interactions. 177:190-195
Chemically induced carcinogenesis models in the rat are widely used for studying the biology of cancer and for developing and evaluating cancer prevention strategies. The azoxymethane(AOM)-induced rat colon tumor is a valuable tool for studying the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431aae7c12487138e01ab9d804359e4c
https://doi.org/10.1016/j.cbi.2008.09.027
https://doi.org/10.1016/j.cbi.2008.09.027
Akademický článek
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Autor:
Putchen Dakshinamoorthy Deepalakshmi, Kumaravelu Parasakthy, Sivasithambaram Niranjali Devaraj, Bezwada Padmavathy, Halagowder Devaraj, Subramaniam Shanthi
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 19:19-25
Alterations in liver microsomal drug-metabolizing enzymes and phospholipids following oral administration of chloroquine to rats for 14 days were investigated. An increase in cytochrome P450 and cytochrome b5 contents and an increase in the activitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052a068c1070fb951ded7bbc8afa9ca9
https://doi.org/10.3164/jcbn.19.19
https://doi.org/10.3164/jcbn.19.19
Publikováno v:
Molecular and cellular biochemistry. 364(1-2)
In general, oxidative stress resulting from an imbalance between prooxidant and antioxidant systems plays an important role in the pathogenesis of cancer. Morin (3,5,7,2′,4′-pentahydroxyflavone), a member of the flavanol group, has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f49f1cb6c67a6abc3b749163a948d5d
https://pubmed.ncbi.nlm.nih.gov/22350814
https://pubmed.ncbi.nlm.nih.gov/22350814