Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sivaraman, Balasubramaniam"'
Autor:
Sivaraman Balasubramaniam, Sajith Vijayan, Liam V. Goldman, Xavier A. May, Kyra Dodson, Sweta Adhikari, Fatima Rivas, Davita L. Watkins, Shana V. Stoddard
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 628-637 (2020)
Guided by computational analysis, herein we report the design, synthesis and evaluation of four novel diazine-based histone deacetylase inhibitors (HDACis). The targets of interest (TOI) are analogues of panobinostat, one of the most potent and versa
Externí odkaz:
https://doaj.org/article/7c1390dbe771440c8d92bddc41f9811b
Autor:
Sung-Jin Park, Beomsue Kim, Sejong Choi, Sivaraman Balasubramaniam, Sung-Chan Lee, Jung Yeol Lee, Heon Seok Kim, Jun-Young Kim, Jong-Jin Kim, Yong-An Lee, Nam-Young Kang, Jin-Soo Kim, Young-Tae Chang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Attempts to image activated macrophages in vivo have been hampered by selectivity and delivery problems. Here the authors develop a small molecule fluorescent probe specific to activated M1 and M2 macrophages, identify the orphan receptor Slc18b1/SLC
Externí odkaz:
https://doaj.org/article/a80a5a7ec76b4b3aaca86bee713b6628
Autor:
Davita L. Watkins, Sweta Adhikari, Sajith Vijayan, Shana V. Stoddard, Xavier A. May, Kyra Dodson, Sivaraman Balasubramaniam, Liam Goldman, Fatima Rivas
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 628-637 (2020)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Guided by computational analysis, herein we report the design, synthesis and evaluation of four novel diazine-based histone deacetylase inhibitors (HDACis). The targets of interest (TOI) are analogues of panobinostat, one of the most potent and versa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c229593c46dd1ab9948b89769cc203
https://doaj.org/article/7c1390dbe771440c8d92bddc41f9811b
https://doaj.org/article/7c1390dbe771440c8d92bddc41f9811b
Autor:
Heon Seok Kim, Beomsue Kim, Jong-Jin Kim, Jun-Young Kim, Sungjin Park, Sivaraman Balasubramaniam, Sung-Chan Lee, Sejong Choi, Jin-Soo Kim, Jung Yeol Lee, Nam-Young Kang, Yong-An Lee, Young-Tae Chang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Nature Communications
Nature Communications
Activated macrophages have the potential to be ideal targets for imaging inflammation. However, probe selectivity over non-activated macrophages and probe delivery to target tissue have been challenging. Here, we report a small molecule probe specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581dfac5f3b193f9ccf3d7fa9e8f6c19
https://doaj.org/article/a80a5a7ec76b4b3aaca86bee713b6628
https://doaj.org/article/a80a5a7ec76b4b3aaca86bee713b6628
Autor:
Vidhya Rangaswamy, Swati Badgujar, Sivaraman Balasubramaniam, Vinod Puthan Veetil, Sneh Sanjay Badle
Publikováno v:
Chembiochem : a European journal of chemical biology. 22(4)
A method for producing buta-1,3-diene (1,3-BD) by an amalgamation of chemical and biological approaches with syngas as the carbon source is proposed. Syngas is converted to the central intermediate, acetyl-CoA, by microorganisms through a tetrahydrof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc837fee9013d44183b9d58d9943c690
https://pubmed.ncbi.nlm.nih.gov/32991036
https://pubmed.ncbi.nlm.nih.gov/32991036
Publikováno v:
Synthesis. 50:968-983
FTY720 {fingolimod hydrochloride, 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride}, a novel immunosuppressant, was discovered by chemical modification based on the structure activity relationships of ISP-I (myriocin), a metabolite of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df99007110eaf4d7d4d917153763e84
https://doi.org/10.1055/s-0036-1591877
https://doi.org/10.1055/s-0036-1591877
Autor:
Tiwari, Praveen Kumar1, Sivaraman, Balasubramaniam1, Aidhen, Indrapal Singh1 isingh@iitm.ac.in
Publikováno v:
European Journal of Organic Chemistry. 7/7/2017, Vol. 2017 Issue 25, p3594-3605. 12p.
Publikováno v:
MOJ Bioorganic & Organic Chemistry. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fccd8962122f1d8826f6319d605a499
https://doi.org/10.15406/mojboc.2018.02.0062
https://doi.org/10.15406/mojboc.2018.02.0062
Publikováno v:
International Review for Environmental Strategies. Summer2004, Vol. 5 Issue 1, p257-272. 16p. 1 Chart, 5 Graphs.
Publikováno v:
Synthesis. 2008:3707-3738
N-Methoxy- N-methylamide,popularly addressed as the Weinreb amide, has surfaced as an amidewith a difference. This amide has served as an excellent acylatingagent for organolithium or organomagnesium reagents and as a robustequivalent for an aldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9d132b61e2226fd28633eaab1f9ab54
https://doi.org/10.1055/s-0028-1083226
https://doi.org/10.1055/s-0028-1083226