Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sivanarayana Mandalapu"'
Autor:
Radha Gopal, Benjamin Lee, Kevin J. McHugh, Helen E. Rich, Krishnaveni Ramanan, Sivanarayana Mandalapu, Michelle E. Clay, Philip J. Seger, Richard I. Enelow, Michelle L. Manni, Keven M. Robinson, Javier Rangel-Moreno, John F. Alcorn
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza is a common respiratory virus that infects between 5 and 20% of the US population and results in 30,000 deaths annually. A primary cause of influenza-associated death is secondary bacterial pneumonia. We have previously shown that influenza
Externí odkaz:
https://doaj.org/article/c296759483a54f1c982c9edb7a45130c
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82865 (2013)
Influenza viruses pose a significant health risk and annually impose a great cost to patients and the health care system. The molecular determinants of influenza severity, often exacerbated by secondary bacterial infection, are largely unclear. We ge
Externí odkaz:
https://doaj.org/article/c056fea55f474c76b786caa432886f2a
Autor:
Kevin J. McHugh, Keven M. Robinson, Sivanarayana Mandalapu, Radha Gopal, Michelle L. Manni, John F. Alcorn, Benjamin Lee
Publikováno v:
ImmunoHorizons. 1:81-91
Influenza is an annual, global healthcare concern. Secondary bacterial pneumonia is a severe complication associated with primary influenza virus infection that often results in critical morbidity and mortality. We have identified influenza-induced s
Autor:
Sivanarayana Mandalapu, John F. Alcorn, Michelle L. Manni, Kevin J. McHugh, Paul L. Dudas, M. Merle Elloso
Publikováno v:
The Journal of Immunology. 196:963-977
IL-13 and IL-17A, produced mainly by Th2 and Th17 cells, respectively, have an influential role in asthma pathogenesis. We examined the role of IL-13 and IL-17A in mediating airway hyperresponsiveness (AHR), lung inflammation, and mucus metaplasia in
Autor:
Kevin J. McHugh, Javier Rangel-Moreno, Helen E. Rich, Benjamin Lee, Michelle E. Clay, Sivanarayana Mandalapu, Keven M. Robinson, Krishnaveni Ramanan, Philip J. Seger, Radha Gopal, Michelle L. Manni, John F. Alcorn, Richard I. Enelow
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Influenza is a common respiratory virus that infects between 5 and 20% of the US population and results in 30,000 deaths annually. A primary cause of influenza-associated death is secondary bacterial pneumonia. We have previously shown that influenza
Autor:
Kevin J. McHugh, Chen Chen, Benjamin Lee, Keven M. Robinson, Michelle E. Clay, John F. Alcorn, Richard I. Enelow, Sivanarayana Mandalapu, Patricia J. Dubin, Erich V. Scheller, Y. Peter Di
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 309:L158-L167
Suppression of type 17 immunity by type I interferon (IFN) during influenza A infection has been shown to enhance susceptibility to secondary bacterial pneumonia. Although this mechanism has been described in coinfection with gram-positive bacteria,
Autor:
John F. Alcorn, Jay K. Kolls, Jose M. Lora, Michelle L. Manni, Andres Salmeron, Sivanarayana Mandalapu
Publikováno v:
Scientific Reports
Atopic asthma is a prevalent respiratory disease that is characterized by inflammation, mucus hypersecretion, and airway hyperresponsiveness. The complexity of this heterogeneous disorder has commanded the need to better define asthma phenotypes base
Autor:
M. Merle Elloso, Erich V. Scheller, Sivanarayana Mandalapu, Jay K. Kolls, John F. Alcorn, Sally E. Wenzel, Michelle L. Manni, John B. Trudeau
Publikováno v:
Mucosal immunology
Asthma is a common respiratory disease affecting approximately 300 million people worldwide. Airway inflammation is thought to contribute to asthma pathogenesis, but the direct relationship between inflammation and airway hyperresponsiveness remains
Autor:
Cheryl L. Fattman, Jay K. Kolls, John F. Alcorn, Erich V. Scheller, Richard I. Enelow, Kevin J. McHugh, Derek Pociask, Sivanarayana Mandalapu
Publikováno v:
The American Journal of Pathology. 182(4):1286-1296
Influenza infection is widespread in the United States and the world. Despite low mortality rates due to infection, morbidity is common and little is known about the molecular events involved in recovery. Influenza infection results in persistent dis
Autor:
Keven M. Robinson, Erich V. Scheller, Richard I. Enelow, Jay K. Kolls, Sivanarayana Mandalapu, Benjamin Lee, John F. Alcorn
Publikováno v:
Respiratory Research
Background Influenza is a common respiratory virus and Staphylococcus aureus frequently causes secondary pneumonia during influenza infection, leading to increased morbidity and mortality. Influenza has been found to attenuate subsequent Type 17 immu