Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sivan Zeno"'
Publikováno v:
Current Molecular Medicine. 12:494-501
By exposing cells of the U118MG glioblastoma cell line to protoporphyrin IX (PPIX) in culture, we found that the 18 kDa mitochondrial translocator protein (TSPO) prevents intracellular accumulation of PPIX. In particular, TSPO knockdown by stable tra
Autor:
Ofer Ben-Izhak, Leo Veenman, Moshe Gavish, Rafael M. Nagler, Sivan Zeno, Dana Savulescu, Ella Krayzler, Sharon Akrish, Irina Otradnov, Svetlana Leschiner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1802:454-461
Oral cancer features high rates of mortality and morbidity, and is in dire need for new approaches. In the present study we analyzed 18 kDa translocator protein (TSPO) expression in oral (tongue) cancer tumors by immunohistochemistry. We also assayed
Autor:
Wilfried Kugler, Yulia Shandalov, Sivan Zeno, Moshe Gavish, Karen Linnemannstöns, Julia von Alten, Leo Veenman, Max Lakomek
Publikováno v:
Apoptosis. 15:753-768
Erucylphosphohomocholine (ErPC3, Erufosine™) was reported previously to induce apoptosis in otherwise highly apoptosis-resistant malignant glioma cell lines while sparing their non-tumorigenic counterparts. We also previously found that the mitocho
Publikováno v:
Biochemistry. 48:4652-4661
The 18 kDa translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor, has been reported to be closely associated with the mitochondrial permeability transition pore (MPTP). TSPO is believed to exert pro-apoptotic func
Autor:
Silke Kietz, Julia Bode, Michal Gaitner, Beatriz Caballero, Wilfried Kugler, Yelena Peʼer, Max Lakomek, Sivan Zeno, Moshe Gavish, Leo Veenman
Publikováno v:
Pharmacogenetics and genomics. 22(8)
Objective Previously, several important roles for glutamate have been described for the biology of primary brain tumors. For example, glutamate has been suggested to promote glioma cell proliferation by the activation of the 2-amino-3-(5-methyl-3-oxo
Autor:
Kugler, Wilfried1, Veenman, Leo2, Shandalov, Yulia2, Leschiner, Svetlana2, Spanier, Ilana2, Lakomek, Max1, Gavish, Moshe2 mgavish@techunix.technion.ac.il
Publikováno v:
Cellular Oncology. Sep2008, Vol. 30 Issue 5, p435-450. 16p. 1 Black and White Photograph, 1 Diagram, 1 Chart, 6 Graphs.
Autor:
Veenman, Leo, Alten, Julia, Linnemannstöns, Karen, Shandalov, Yulia, Zeno, Sivan, Lakomek, Max, Gavish, Moshe, Kugler, Wilfried
Publikováno v:
Apoptosis; Jul2010, Vol. 15 Issue 7, p753-768, 16p, 1 Diagram, 10 Graphs