Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sivan Navon"'
Publikováno v:
eLife, Vol 3 (2014)
In all living organisms, ribosomes translating membrane proteins are targeted to membrane translocons early in translation, by the ubiquitous signal recognition particle (SRP) system. In eukaryotes, the SRP Alu domain arrests translation elongation o
Externí odkaz:
https://doaj.org/article/364ccf0da3bf4d2ba8b7b9b272dd0125
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004084 (2014)
Deciphering the architecture of the tRNA pool is a prime challenge in translation research, as tRNAs govern the efficiency and accuracy of the process. Towards this challenge, we created a systematic tRNA deletion library in Saccharomyces cerevisiae,
Externí odkaz:
https://doaj.org/article/789d953b2e99460f96513f208f8a766e
Autor:
Sivan Navon, Yuval Dorfan, Tamir Tuller, Orna Dahan, Asaf Carmi, Tao Pan, Yitzhak Pilpel, John M. Zaborske, Itay Furman, Kalin Vestsigian
Publikováno v:
Cell
Recent years have seen intensive progress in measuring protein translation. However, the contributions of coding sequences to the efficiency of the process remain unclear. Here, we identify a universally conserved profile of translation efficiency al
Publikováno v:
eLife
eLife, Vol 3 (2014)
eLife, Vol 3 (2014)
In all living organisms, ribosomes translating membrane proteins are targeted to membrane translocons early in translation, by the ubiquitous signal recognition particle (SRP) system. In eukaryotes, the SRP Alu domain arrests translation elongation o
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004084 (2014)
PLoS Genetics
PLoS Genetics
Deciphering the architecture of the tRNA pool is a prime challenge in translation research, as tRNAs govern the efficiency and accuracy of the process. Towards this challenge, we created a systematic tRNA deletion library in Saccharomyces cerevisiae,
The role of codon selection in regulation of translation efficiency deduced from synthetic libraries
Autor:
Sivan Navon, Yitzhak Pilpel
Publikováno v:
Genome Biology
Background: Translation efficiency is affected by a diversity of parameters, including secondary structure of the transcript and its codon usage. Here we examine the effects of codon usage on translation efficiency by re-analysis of previously constr