Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sivan Galai"'
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Supplementary Figures 1-5 further support our findings regarding the contribution to the maintenance of intracellular pH for ASS1 downregulated cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf590f6c6dae26b958754b6195138c9
https://doi.org/10.1158/0008-5472.22422482
https://doi.org/10.1158/0008-5472.22422482
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Downregulation of the urea cycle enzyme argininosuccinate synthase (ASS1) by either promoter methylation or by HIF1α is associated with increased metastasis and poor prognosis in multiple cancers. We have previously shown that in normoxic conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0c71bc872afa3968a802eb42fd39f4
https://doi.org/10.1158/0008-5472.c.6511238.v1
https://doi.org/10.1158/0008-5472.c.6511238.v1
Autor:
Omer Goldman, Lital N. Adler, Emma Hajaj, Tommaso Croese, Naama Darzi, Sivan Galai, Hila Tishler, Yarden Ariav, Dor Lavie, Liat Fellus-Alyagor, Roni Oren, Yuri Kuznetsov, Eyal David, Rami Jaschek, Chani Stossel, Oded Singer, Sergey Malitsky, Renana Barak, Rony Seger, Neta Erez, Ido Amit, Amos Tanay, Ann Saada, Talia Golan, Tamar Rubinek, Joo Sang Lee, Shay Ben-Shachar, Ido Wolf, Ayelet Erez
Publikováno v:
Cancer Discovery.
Multiple studies identified metabolic changes within the tumor and its microenvironment during carcinogenesis. Yet, the mechanisms by which tumors affect the host metabolism are unclear. We find that systemic inflammation induced by the cancer leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05eb29f69e66673fbd9fc126ad9bd8ae
https://doi.org/10.1158/2159-8290.cd-22-1062
https://doi.org/10.1158/2159-8290.cd-22-1062
Autor:
Hadas Landesman, Ayelet Erez, Omer Goldman, Sergey Malitsky, Sivan Galai, Alexander Brandis, Tevi Mehlman, Keyur Talsania, S. Eleonore Koehler, Yael Kuperman, Eytan Ruppin, Lisha Qiu Jin Lim, Igor Ulitsky, Angel Porgador, Yongmei Zhao, Roni Oren, Shaul Lerner, Joo Sang Lee, Maxim Itkin, Hila Weiss Tishler, Rotem Katzir, Shiran Rabinovich, Nir Peled, Noa Stettner, Lital Adler, Yuri Kuznetsov, Rom Keshet, Muhammed Iraqi, Tsai-wei Shen, Yarden Ariav
Publikováno v:
Nature Cancer
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Argininosuccinate synthase (ASS1) downregulation in different tumors has been shown to support cell proliferation and yet, in several common cancer subsets ASS1 expression associates with poor patient prognosis. Here we demonstrate that ASS1 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193f750c2610f8dd4d6709f2a1e2b1be