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of 2
pro vyhledávání: '"Sivan Abramovitch"'
Autor:
K. Dane Wittrup, Jamie B. Spangler, Douglas A. Lauffenburger, Sivan Abramovitch, Forest M. White, Yosef Yarden, Jason R. Neil
Due to its common dysregulation in epithelial-based cancers and extensive characterization of its role in tumor growth, epidermal growth factor receptor (EGFR) is a highly validated target for anticancer therapies. There has been particular interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb231f7735d25cec5b779264bb8d6f
https://europepmc.org/articles/PMC2922117/
https://europepmc.org/articles/PMC2922117/
Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases
Autor:
Shelly Zaffryar, Ofra Kessler, Gal Akiri, Sivan Abramovitch, Boaz Kigel, Asya Varshavsky, Gera Neufeld
Publikováno v:
Cancer research. 68(17)
Semaphorin-3B (sema3B) and semaphorin-3F (sema3F) are secreted tumor suppressors of lung cancer. Sema3F functions as an antiangiogenic factor that repels endothelial cells and compromises their proliferation/survival. However, tumor cells expressing