Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Sivagurunathan S"'
Autor:
Marko Frings, Matthias Welsner, Christin Mousa, Sebastian Zensen, Luca Salhöfer, Mathias Meetschen, Nikolas Beck, Denise Bos, Dirk Westhölter, Johannes Wienker, Christian Taube, Lale Umutlu, Benedikt M. Schaarschmidt, Michael Forsting, Johannes Haubold, Sivagurunathan Sutharsan, Marcel Opitz
Publikováno v:
European Radiology Experimental, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Background Regular disease monitoring with low-dose high-resolution (LD-HR) computed tomography (CT) scans is necessary for the clinical management of people with cystic fibrosis (pwCF). The aim of this study was to compare the image quality
Externí odkaz:
https://doaj.org/article/75e5a7b2ebf64d7a8ed75d8aa4daacf1
Akademický článek
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Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-5 (2024)
Abstract Liver-related side effects are a known complication of treatment with elexacaftor/tezacaftor/ivacaftor (ETI) for cystic fibrosis (CF). Gilbert’s syndrome is caused by a genetic mutation that reduces activity of the enzyme UDP glucuronosylt
Externí odkaz:
https://doaj.org/article/e7f10fbf6acf4c76954ab790ee4ad480
Autor:
Sivagurunathan Sutharsan, Rainald Fischer, Wolfgang Gleiber, Alex Horsley, Jeff Crosby, Shuling Guo, Shuting Xia, Rosie Yu, Kenneth B. Newman, J. Stuart Elborn
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Background Hyperactivity of epithelial sodium channel (ENaC) with increased sodium absorption is a feature of cystic fibrosis (CF). ION-827359 is a 2.5-generation antisense oligonucleotide targeted to reduce ENaC protein. This study evaluated ION-827
Externí odkaz:
https://doaj.org/article/85b98b185ea54aedaea0d4fbe75abcce
Autor:
Dirk Westhölter, Johannes Haubold, Matthias Welsner, Luca Salhöfer, Johannes Wienker, Sivagurunathan Sutharsan, Svenja Straßburg, Christian Taube, Lale Umutlu, Benedikt M. Schaarschmidt, Sven Koitka, Sebastian Zensen, Michael Forsting, Felix Nensa, René Hosch, Marcel Opitz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract A poor nutritional status is associated with worse pulmonary function and survival in people with cystic fibrosis (pwCF). CF transmembrane conductance regulator modulators can improve pulmonary function and body weight, but more data is need
Externí odkaz:
https://doaj.org/article/f083b010ca674e2bb98c97dac99faa1a
Publikováno v:
European Respiratory Review, Vol 33, Iss 173 (2024)
Bronchiectasis presents a significant challenge due to its rising prevalence, associated economic burden and clinical heterogeneity. This review synthesises contemporary understanding and literature of bronchiectasis exacerbations, addressing the tra
Externí odkaz:
https://doaj.org/article/16f9bebe5a52456d8ba03f22ea84e76e
Akademický článek
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Autor:
Wolfgang Gruber, Florian Stehling, Christopher Blosch, Stefanie Dillenhoefer, Margarete Olivier, Folke Brinkmann, Cordula Koerner-Rettberg, Sivagurunathan Sutharsan, Uwe Mellies, Christian Taube, Matthias Welsner
Publikováno v:
Frontiers in Sports and Active Living, Vol 6 (2024)
BackgroundHabitual physical activity (PA) and exercise training are accepted as important aspects of care for people with cystic fibrosis (pwCF) to improve health-related measures of physical fitness, which in turn have a positive impact on quality o
Externí odkaz:
https://doaj.org/article/2e06f6f2ea37444f846398237506ca1b
Akademický článek
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Autor:
Ute Niehammer, Svenja Straßburg, Sivagurunathan Sutharsan, Christian Taube, Matthias Welsner, Florian Stehling, Raphael Hirtz
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The present study evaluates personality traits in adult patients with cystic fibrosis (CF) and correlates these results with health-related quality of life (HRQoL) and other clinical parameters indicative of disease severity. Meth
Externí odkaz:
https://doaj.org/article/82415a2bfefe476e8eb2da5c605af190