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pro vyhledávání: '"Siva Thirugnanam"'
Autor:
Siva Thirugnanam, Namita Rout
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4768-4786 (2024)
The emergence of combination antiretroviral therapy (cART) has greatly transformed the life expectancy of people living with HIV (PWH). Today, over 76% of the individuals with HIV have access to this life-saving therapy. However, this progress has co
Externí odkaz:
https://doaj.org/article/f6c498fa5eb54091a98cb615383d642c
Autor:
Siva Thirugnanam, Chenxiao Wang, Chen Zheng, Brooke F. Grasperge, Prasun K. Datta, Jay Rappaport, Xuebin Qin, Namita Rout
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8702 (2024)
HIV-induced persistent immune activation is a key mediator of inflammatory comorbidities such as cardiovascular disease (CVD) and neurocognitive disorders. While a preponderance of data indicate that gut barrier disruption and microbial translocation
Externí odkaz:
https://doaj.org/article/283dd0ea4de64f248cffd1778675d1c4
Publikováno v:
Viruses, Vol 15, Iss 9, p 1944 (2023)
Previous studies have indicated that the loss of CD161-expressing CD4+ Th17 cells is linked to the progression of chronic HIV. These cells are significantly depleted in peripheral blood and gut mucosa of HIV-infected individuals, contributing to infl
Externí odkaz:
https://doaj.org/article/229954ad75884ee9ba3d2d923ae8c5a3
Autor:
Farzaneh Fakharian, Siva Thirugnanam, David A. Welsh, Woong-Ki Kim, Jay Rappaport, Kyle Bittinger, Namita Rout
Publikováno v:
Microorganisms, Vol 11, Iss 7, p 1849 (2023)
The gut microbiome plays a critical role in maintaining overall health and immune function. However, dysbiosis, an imbalance in microbiome composition, can have profound effects on various aspects of human health, including susceptibility to viral in
Externí odkaz:
https://doaj.org/article/50dffbc9e0864d39be6a6ca0ce54d11f