Výsledky vyhledávání - "Siv M. Osterman-Golkar"

Epoxybutene–Hemoglobin Adducts in Rats and Mice: Dose Response for Formation and Persistence During and Following Long-Term Low-Level Exposure to Butadiene

Autor: Matthew S. Bryant, Arden James, James A. Bond, Owen R. Moss, Max J. Turner, Siv M. Osterman-Golkar

Publikováno v: Toxicology and Applied Pharmacology. 150:166-173

Measurement of specific adducts to hemoglobin can be used to establish the dosimetry of electrophilic compounds and metabolites in experimental animals and in humans. The purpose of this study was to investigate the dose response for adduct formation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adac1f1549e463f34cca1ca81bf0269
https://doi.org/10.1006/taap.1998.8376

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Determination of mutagenicity in tissues of transgenic mice following exposure to 1,3-butadiene and N-ethyl-N-nitrosourea

Autor: Owen R. Moss, György A. Csanády, James A. Bond, Leslie Recio, Brian Myhr, Siv M. Osterman-Golkar, Max J. Turner

Publikováno v: Toxicology and Applied Pharmacology. 117:58-64

1,3-Butadiene (BD) is carcinogenic in the B6C3F1 mouse in multiple organs, including lung and liver. We conducted a study to measure the frequency of BD mutations in mouse tissues using a transgenic mouse (Muta mouse; MM). MM is a BALB c × DBA 2 (CD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399f799d888f0bd64343dad82c7d62bc
https://doi.org/10.1016/0041-008x(92)90217-g

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