Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Siu-Hong Ho"'
Autor:
Hector Cordero, Rodney G. King, Pranay Dogra, Chloe Dufeu, Sarah B. See, Alexander M. Chong, Anne-Catrin Uhlemann, Siu-Hong Ho, David M. Kalfa, Emile A. Bacha, John F. Kearney, Emmanuel Zorn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.
Externí odkaz:
https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
Autor:
Shannon Rausser, Caroline Trumpff, Marlon A McGill, Alex Junker, Wei Wang, Siu-Hong Ho, Anika Mitchell, Kalpita R Karan, Catherine Monk, Suzanne C Segerstrom, Rebecca G Reed, Martin Picard
Publikováno v:
eLife, Vol 10 (2021)
Using a high-throughput mitochondrial phenotyping platform to quantify multiple mitochondrial features among molecularly defined immune cell subtypes, we quantify the natural variation in mitochondrial DNA copy number (mtDNAcn), citrate synthase, and
Externí odkaz:
https://doaj.org/article/66750d7ee5894ea68f42b14e43507f68
Autor:
Brahma V. Kumar, Wenji Ma, Michelle Miron, Tomer Granot, Rebecca S. Guyer, Dustin J. Carpenter, Takashi Senda, Xiaoyun Sun, Siu-Hong Ho, Harvey Lerner, Amy L. Friedman, Yufeng Shen, Donna L. Farber
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2921-2934 (2017)
Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRMs remain unclear. Here, we use a unique human tissue resource to determine whether hum
Externí odkaz:
https://doaj.org/article/f3e9780754764601b97c47d562f49b9a
Autor:
Emmanuel Zorn, Emile A. Bacha, Hector Cordero, Siu-Hong Ho, Alexander M. Chong, Pranay Dogra, Anne-Catrin Uhlemann, David Kalfa, Rodney G. King, Sarah B. See, John F. Kearney, Chloe Dufeu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
The thymus is a central lymphoid organ primarily responsible for the development of T cells. A small proportion of B cells, however, also reside in the thymus to assist negative selection of self-reactive T cells. Here we show that the thymus of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68151cd8678b003747cf9cdff0e249e5
https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
Autor:
Andrea Vecchione, Rachel Madley, Nichole Danzl, Chiara Borsotti, Mohsen Khosravi Marharlooei, Hao-Wei Li, Grace Nauman, Xiaolan Ding, Siu-Hong Ho, Georgia Fousteri, Megan Sykes
Publikováno v:
Clin Immunol
Interactions between B cells and CD4(+) T cells play a central role in the development of Type 1 Diabetes (T1D). Two helper cell subsets, follicular (Tfh) and peripheral (Tph) helper T cells, are increased in patients with T1D but their role in drivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f420dac92564bdd0fb2a29f65b4b5275
https://pubmed.ncbi.nlm.nih.gov/35644520
https://pubmed.ncbi.nlm.nih.gov/35644520
Autor:
Megan Sykes, Felix Sellberg, Manuel Alfredo Podestà, Christian Binder, Aleksandar Obradovic, Susan DeWolf, Elizabeth E. Waffarn, David Berglund, Brittany Shonts, Siu-hong Ho, Nichole Danzl
Publikováno v:
Am J Transplant
Siplizumab, a humanized anti-CD2 monoclonal antibody, has been used in conditioning regimens for hematopoietic cell transplantation and tolerance induction with combined kidney-bone marrow transplantation. Siplizumab-based tolerance induction regimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fb1b494e465cbb3f5ceb2f882eac29
https://doi.org/10.1111/ajt.15533
https://doi.org/10.1111/ajt.15533
Autor:
Alex Junker, Martin Picard, Anika Mitchell, Siu-hong Ho, Wei Wang, Caroline Trumpff, Rebecca G. Reed, Suzanne C. Segerstrom, Marlon A. McGill, Kalpita R Karan, Shannon Rausser, Catherine Monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a2fcc237d32fbd791910fa50daf6652
https://doi.org/10.7554/elife.70899.sa2
https://doi.org/10.7554/elife.70899.sa2
Autor:
Alex Junker, Wei Wang, Suzanne C. Segerstrom, Marlon A. McGill, Rebecca G. Reed, Kalpita R Karan, Shannon Rausser, Martin Picard, Siu-hong Ho, Caroline Trumpff, Catherine Monk, Anika Mitchell
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Using a high-throughput mitochondrial phenotyping platform to quantify multiple mitochondrial features among molecularly defined immune cell subtypes, we quantify the natural variation in mitochondrial DNA copy number (mtDNAcn), citrate synthase, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800467ed4e7c59ce5ff1d5905002d436
https://pubmed.ncbi.nlm.nih.gov/34698636
https://pubmed.ncbi.nlm.nih.gov/34698636
Autor:
Sigal Kofman, Jonah Zitsman, Megan Sykes, Jeffrey Stern, David C. Woodland, Siu Hong Ho, Leo Buhler, Adam Griesemer, Paula Alonso-Guallart, Raimon Duran-Struuck, Hugo P. Sondermeijer
Publikováno v:
Am J Transplant
American Journal of Transplantation, 19(8), 2186-2198. Wiley
American Journal of Transplantation, 19(8), 2186-2198. Wiley
Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6fb9ff3da12aee696083a49433d942
https://doi.org/10.1111/ajt.15313
https://doi.org/10.1111/ajt.15313
Autor:
Thomas Savage, Peter Liou, Suxiao Yang, Adam Griesemer, Eline T. Luning Prak, Kristjana Frangaj, Megan Sykes, Mercedes Martinez, Wenzhao Meng, Kortney Rogers, Yufeng Shen, Wang Z, Julien Zuber, Jianing Fu, Alina Iuga, Aaron M. Rosenfeld, Brittany Shonts, Tomoaki Kato, Aleksandar Obradovic, Elizabeth E. Waffarn, Sai-Ping Lau, Nichole M. Danzl, Shilpa Ravella, Siu-hong Ho, Prakash Satwani
Publikováno v:
J Clin Invest
In humans receiving intestinal transplantation (ITx), long-term multilineage blood chimerism often develops. Donor T cell macrochimerism (≥4%) frequently occurs without graft-versus-host disease (GVHD) and is associated with reduced rejection. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d20a084a0b36b525241366fcdd33ba1
https://europepmc.org/articles/PMC8062082/
https://europepmc.org/articles/PMC8062082/