Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Siu Tim Cheung"'
Autor:
Phyllis F. Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine H. L. Siu, Linda W. C. Ng, Karl S. Lang, Lamin B. Cham, Daniel R. Engel, Camille Soun, Igor Cima, Björn Scheffler, Jana K. Striefler, Marianne Sinn, Marcus Bahra, Uwe Pelzer, Helmut Oettle, Peter Markus, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Konstantinos Savvatakis, Sven-Thorsten Liffers, Smiths S. Lueong, Christian Neander, Anna Bazarna, Xin Zhang, Annette Paschen, Howard C. Crawford, Anthony W. H. Chan, Siu Tim Cheung, Jens T. Siveke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Immune responses to pancreatic ductal adenocarcinoma can be inhibited by cancer cells. Here the authors show that high levels of progranulin in PDAC inhibits immune responses by reducing MHC class I antigen presentation through enhanced degradation o
Externí odkaz:
https://doaj.org/article/c9aa189db2194c2eba13f30f461a6fdd
Autor:
Weitao Lin, Yim Ling Yip, Lin Jia, Wen Deng, Hong Zheng, Wei Dai, Josephine Mun Yee Ko, Kwok Wai Lo, Grace Tin Yun Chung, Kevin Y. Yip, Sau-Dan Lee, Johnny Sheung-Him Kwan, Jun Zhang, Tengfei Liu, Jimmy Yu-Wai Chan, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, John Malcolm Nicholls, Pierre Busson, Xuefeng Liu, Alan Kwok Shing Chiang, Kwai Fung Hui, Hin Kwok, Siu Tim Cheung, Yuk Chun Cheung, Chi Keung Chan, Bin Li, Annie Lai-Man Cheung, Pok Man Hau, Yuan Zhou, Chi Man Tsang, Jaap Middeldorp, Honglin Chen, Maria Li Lung, Sai Wah Tsao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The lack of appropriate models restricts pre-clinical research for nasopharyngeal carcinoma (NPC). Here the authors report the development and characterization of NPC patient-derived xenografts (PDXs), and EBV positive NPC cell line from patient tumo
Externí odkaz:
https://doaj.org/article/0bf1deca4e9646d1b93328014cc28ef0
Autor:
Yi Pan, Siu Tim Cheung, Joanna Hung Man Tong, Ka Yee Tin, Wei Kang, Raymond Wai Ming Lung, Feng Wu, Hui Li, Simon Siu Man Ng, Tony Wing Chung Mak, Ka Fai To, Anthony Wing Hung Chan
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Granulin epithelin precursor (GEP) is reported to function as a growth factor stimulating proliferation and migration, and conferring chemoresistance in many cancer types. However, the expression and functional roles of GEP in col
Externí odkaz:
https://doaj.org/article/e1ecd2eee803457da7ec68db75e52266
Autor:
Chi Wai Yip, Ching Yan Lam, Terence C. W. Poon, Tan To Cheung, Phyllis F. Y. Cheung, Sze Wai Fung, Xiao Qi Wang, Idy C.Y. Leung, Linda W. C. Ng, Chung Mau Lo, George S. W. Tsao, Siu Tim Cheung
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Granulin-epithelin precursor (GEP) is a secretory growth factor, which has been demonstrated to control cancer growth, invasion, drug resistance and immune escape. Our previous studies and others also demonstrated its potential in
Externí odkaz:
https://doaj.org/article/6bc88201718349b7a6a31d705161c1dd
Autor:
Siu Tim Cheung, Chi Leung Liu, Jeremy P.H. Chow, Yuk Ting Lee, Ying Chi Ip, Jenny C.Y. Ho, Sheung Tat Fan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 9, Pp 696-701 (2006)
BACKGROUND: We have previously reported that tissue expression levels of transcript AA454543 in hepatocellular carcinoma (HCC) are significantly higher than those of normal livers, livers with cirrhosis, and livers with hepatitis. In addition, a high
Externí odkaz:
https://doaj.org/article/7de092c224cd4a70906f2d56673bb0d0
Autor:
Siu Tim Cheung, Jenny C.Y. Ho, Ka Ling Leung, Xin Chen, Daniel Y.T. Fong, Samuel So, Sheung Tat Fan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 2, Pp 91-98 (2005)
BACKGROUND: We have previously reported on the cDNA microarray gene expression profiles of hepatocellular carcinomas (HCCs). Among the genes that show prognostic significance and are overexpressed in tumor compared with adjacent nontumorous liver, tr
Externí odkaz:
https://doaj.org/article/8b28d007b5ed41139e5d301918ff5681
Autor:
Ching Yan Lam, Chi Wai Yip, Terence C W Poon, Christine K C Cheng, Eddy W Y Ng, Nicholas C L Wong, Phyllis F Y Cheung, Paul B S Lai, Irene O L Ng, Sheung Tat Fan, Siu Tim Cheung
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40324 (2012)
BACKGROUND AND AIM: Granulin-epithelin precursor (GEP) has previously been reported to control cancer growth, invasion, chemo-resistance, and served as novel therapeutic target for cancer treatment. However, the nature and characteristics of GEP inte
Externí odkaz:
https://doaj.org/article/f149f9647d2245889a6f20ab06cf103c
Autor:
Samantha Wei-Man Lun, Siu Tim Cheung, Phyllis Fung Yi Cheung, Ka-Fai To, John Kong-Sang Woo, Kwong-Wai Choy, Chit Chow, Chartia Ching-Mei Cheung, Grace Tin-Yun Chung, Alice Suk-Hang Cheng, Chun-Wai Ko, Sai-Wah Tsao, Pierre Busson, Margaret Heung-Ling Ng, Kwok-Wai Lo
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52426 (2012)
Nasopharyngeal carcinoma (NPC) is a unique EBV-associated epithelial malignancy, showing highly invasive and metastatic phenotype. Despite increasing evidence demonstrating the critical role of cancer stem-like cells (CSCs) in the maintenance and pro
Externí odkaz:
https://doaj.org/article/ad7648823d3242c1852ce64e303cb2c9
Autor:
Phyllis Fung Yi Cheung, Christine Kei Chin Cheng, Nicholas Chun Lim Wong, Jenny Chung Yee Ho, Chi Wai Yip, Vincent Chi Hang Lui, Annie Nga Yin Cheung, Sheung Tat Fan, Siu Tim Cheung
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28246 (2011)
BACKGROUND AND AIMS: Increasing evidence has suggested that hepatocellular carcinoma (HCC) might originate from a distinct subpopulation called cancer stem cells (CSCs), which are responsible for the limited efficacy of conventional therapies. We hav
Externí odkaz:
https://doaj.org/article/a22462a0fb054dd18d32b07ae945b344
Autor:
Xin Chen, Goberdhan P. Dimri, Siu Tim Cheung, Shi-Ang Huang, Prashant Bommi, Coral Ho, Susie Lee, Chuan-Rui Xu
Supplementary Data from Bmi1 Functions as an Oncogene Independent of Ink4A/Arf Repression in Hepatic Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4b9d9c5398cc08c3680f098d0786c8
https://doi.org/10.1158/1541-7786.22519068
https://doi.org/10.1158/1541-7786.22519068