Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Siu Lung Chan"'
Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia
Autor:
Tung Yan Lo, Anthony Siu Lung Chan, Suet Ting Cheung, Lisa Ying Yung, Manton Man Hon Leung, Yung Hou Wong
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Yang Xin Tang (YXT) is a traditional Chinese herbal preparation which has been reported to improve cognitive function and memory in patients with dementia. As the underlying mechanism of action of YXT has not been elucidated, we e
Externí odkaz:
https://doaj.org/article/b31ead40671b42468a6dd508092d63dd
Autor:
Hao Wu, Vikram Norton, Kui Cui, Bo Zhu, Sudarshan Bhattacharjee, Yao Wei Lu, Beibei Wang, Dan Shan, Scott Wong, Yunzhou Dong, Siu-Lung Chan, Douglas Cowan, Jian Xu, Diane R. Bielenberg, Changcheng Zhou, Hong Chen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Diabetes mellitus is a worldwide health problem that usually comes with severe complications. There is no cure for diabetes yet and the threat of these complications is what keeps researchers investigating mechanisms and treatments for diabetes melli
Externí odkaz:
https://doaj.org/article/f7a87eac62a54436bc5a6738085b0405
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
There has been a rise in the prevalence of non-alcohol fatty liver disease (NAFLD) due to the popularity of western diets and sedentary lifestyles. One quarter of NAFLD patients is diagnosed with non-alcoholic steatohepatitis (NASH), with histologica
Externí odkaz:
https://doaj.org/article/c1ee281f0d274695b4540fb4acab641d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Endocytosis is the process of actively transporting materials into a cell by membrane engulfment. Traditionally, endocytosis was divided into three forms: phagocytosis (cell eating), pinocytosis (cell drinking), and the more selective receptor-mediat
Externí odkaz:
https://doaj.org/article/d456616701d24bf8a61d9c9dda9a5743
Autor:
Lee, Esak, Siu-Lung Chan, Yang Lee, Polacheck, William J., Sukyoung Kwak, Aiyun Wen, Nguyen, Duc-Huy T., Kutys, Matthew L., Alimperti, Stella, Kolarzyk, Anna M., Tae Joon Kwak, Eyckmans, Jeroen, Bielenberg, Diane R., Hong Chen, Chen, Christopher S.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/10/2023, Vol. 120 Issue 41, p1-8, 14p
Autor:
Yunzhou Dong, Beibei Wang, Mulong Du, Bo Zhu, Kui Cui, Siu-Lung Chan, Douglas B. Cowan, Sudarshan Bhattacharjee, Dan Shan, Scott Wong, Joyce Bischoff, MacRae F. Linton, Hong Chen
BACKGROUNDEpsin endocytic adaptor proteins are implicated in the progression of atherosclerosis; however, the underlying molecular mechanisms have not yet been fully defined. In this study, we determined how epsins enhance endothelial-to-mesenchymal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ccc6384a089266c18380d04664ee19
https://doi.org/10.1101/2022.08.09.503324
https://doi.org/10.1101/2022.08.09.503324
Autor:
Qianman Peng, Bo Zhu, Kui Cui, Siu-Lung Chan, Beibei Wang, Scott Wong, Douglas B Cowan, Alex Cuenca, Jifu Ge, Hong Chen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Chronic liver disease, such as non-alcoholic fatty liver disease (NAFLD), is one of the most prevalent diseases, with 4.5 million people diagnosed in the U.S. in 2018. If untreated, fibrosis-induced cirrhosis will eventually develop into
Autor:
Kui Cui, Xinlei Gao, Beibei Wang, Hao Wu, Yunzhou Dong, Yuling Xiao, Xingya Jiang, Siu-Lung Chan, Bo Zhu, Sudarshan Bhattacharjee, Dan Shan, Qianman Peng, Marrina Malovichko, Vikram Norton, Scott Wong, Douglas B Cowan, Sanjay Srivastava, MacRae F Linton, Jinjun Shi, Kaifu Chen, Hong Chen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Resolving atheroma and hindering their transition to vulnerable atherosclerotic plaque is pivotal in preventing deadly episodes such as heart attacks and strokes. Despite recent advances in the treatment, atherosclerosis remains the root cause of dea
Publikováno v:
Metabolism: clinical and experimental. 132
Hyperlipidemia-induced vascular smooth muscle cell (VSMC)-derived foam cell formation is considered a crucial event in the development of atherosclerosis. Since c-Fos emerges as a key modulator of lipid metabolism, we investigated whether c-Fos plays
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
There has been a rise in the prevalence of non-alcohol fatty liver disease (NAFLD) due to the popularity of western diets and sedentary lifestyles. One quarter of NAFLD patients is diagnosed with non-alcoholic steatohepatitis (NASH), with histologica