Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Siu KW"'
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 655 (2010)
Abstract Background The five-year survival rates for head and neck squamous cell carcinoma (HNSCC) patients are less than 50%, and the prognosis has not improved, despite advancements in standard multi-modality therapies. Hence major emphasis is bein
Externí odkaz:
https://doaj.org/article/fd9a1c1be87c49419cf27c540a3fe3c1
Autor:
Shining Loo, Antony Kam, Bamaprasad Dutta, Xiaohong Zhang, Nan Feng, Siu Kwan Sze, Chuan-Fa Liu, Xiaoliang Wang, James P. Tam
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 653-666 (2024)
Stress and illness connection is complex and involves multiple physiological systems. Panax ginsengs, reputed for their broad-spectrum “cure-all” effect, are widely prescribed to treat stress and related illnesses. However, the identity of ginsen
Externí odkaz:
https://doaj.org/article/2d32b34c63674ff9b48d2c7783da2f7e
Autor:
Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-16 (2023)
Abstract Aging results from the accumulation of molecular damage that impairs normal biochemical processes. We previously reported that age‐linked damage to amino acid sequence NGR (Asn‐Gly‐Arg) results in “gain‐of‐function” conformatio
Externí odkaz:
https://doaj.org/article/0e78e068254840989c041da6a4477442
Autor:
Mahmod Panahi, Yoshiki Hase, Xavier Gallart-Palau, Sumonto Mitra, Atsushi Watanabe, Roger C Low, Yumi Yamamoto, Diego Sepulveda-Falla, Atticus H Hainsworth, Masafumi Ihara, Siu Kwan Sze, Matti Viitanen, Homira Behbahani, Raj N Kalaria
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by NOTCH3 mutations. Typical CADASIL is characterised by subcortical ischemic strokes due to severe arteriopathy and fibrotic thic
Externí odkaz:
https://doaj.org/article/11dce6bfaaa44fa2b8315fb967bc1c18
Autor:
Hui Rong Soon, Jessica Ruth Gaunt, Vibhavari Aysha Bansal, Clara Lenherr, Siu Kwan Sze, Toh Hean Ch’ng
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107707- (2023)
Summary: A single episode of pilocarpine-induced status epilepticus can trigger the development of spontaneous recurrent seizures in a rodent model for epilepsy. The initial seizure-induced events in neuronal nuclei that lead to long-term changes in
Externí odkaz:
https://doaj.org/article/322e3ae4da144894a55f6b2021c96d56
Autor:
Xavier Gallart-Palau, Cristina Lorca, María Mulet, José Antonio Sánchez Milán, Julia Lisa, SoFong Cam Ngan, Ranjith Iyappan, Maryam Katoueezadeh, Aida Serra, Siu Kwan Sze
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102524- (2023)
Summary: Vascular dysfunction underlies the onset and progression of many life-threatening diseases, highlighting the need for improved understanding of its molecular basis. Here, we present differential systemic decellularization in vivo (DISDIVO),
Externí odkaz:
https://doaj.org/article/4f5f27c87bbc4afd90234d5bc4986a2e
Publikováno v:
Journal of the American Chemical Society. 123:3006-3012
Proton migration in protonated glycylglycylglycine (GGG) has been investigated by using density functional theory at the B3LYP/6-31++G(d,p) level of theory. On the protonated GGG energy hypersurface 19 critical points have been characterized, 11 as m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2137b9ee3cfbb00d95c259ca0d25af4
https://doi.org/10.1021/ja0015904
https://doi.org/10.1021/ja0015904
Autor:
Piatkivskyi, Andrii, Lau, Justin Kai-Chi, Berden, Giel, Oomens, Jos, Hopkinson, Alan C, Siu, KW Michael, Ryzhov, Victor
Publikováno v:
European Journal of Mass Spectrometry; February 2019, Vol. 25 Issue: 1 p112-121, 10p
Publikováno v:
Cells, Vol 12, Iss 10, p 1401 (2023)
Hypoxia-induced vascular endothelial dysfunction (VED) is a significant contributor to several severe human diseases, including heart disease, stroke, dementia, and cancer. However, current treatment options for VED are limited due to the lack of und
Externí odkaz:
https://doaj.org/article/ba0a05736fd448119c5de55372e432fe
Autor:
Ser Sue Ng, Jung Eun Park, Wei Meng, Christopher P. Chen, Raj N. Kalaria, Neil E. McCarthy, Siu Kwan Sze
Publikováno v:
ACS Omega, Vol 5, Iss 23, Pp 13528-13540 (2020)
Externí odkaz:
https://doaj.org/article/c8a7bd1b60b94bb9938f8f6ef03eb4e5