Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Siu Hung Cheung"'
Publikováno v:
Statistics in medicineREFERENCES. 41(25)
In clinical trials, comparisons of treatments with ordinal responses are frequently conducted using the proportional odds model. However, the use of this model necessitates the adoption of the proportional odds assumption, which may not be appropriat
Publikováno v:
Statistical methods in medical research. 31(8)
Recurrent event responses are frequently encountered during clinical trials of treatments for certain diseases, such as asthma. The recurrence rates of different treatments are often compared by applying the negative binomial model. In addition, a ba
Publikováno v:
Communications in Statistics - Theory and Methods. 51:249-266
Non inferiority (NI) trials with the possibility of multiple experimental treatments have been increasingly used to find substitutes for standard therapies (e.g., to reduce side effects). NI trials...
Publikováno v:
Journal of the Korean Statistical Society. 49:1238-1254
Non-inferiority (NI) trials have gained recognition as an effective tool with which to search for substitutes for a standard treatment that is associated with certain undesirable features, such as adverse side-effects, an exorbitant cost, or an extre
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11182, p 11182 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 11182, p 11182 (2021)
In recent years, several publications reported that nanoparticles larger than the kidney filtration threshold were found intact in the urine after being injected into laboratory mice. This theoretically should not be possible, as it is widely known t
Publikováno v:
Computational Statistics & Data Analysis. 124:168-179
In clinical studies, patients usually accrue sequentially. The response-adaptive design has been shown to be a valuable treatment allocation apparatus that skews the treatment allocation probabilities to achieve certain objectives such as reducing th
Publikováno v:
Computational Statistics & Data Analysis. 104:223-232
In clinical studies, treatment responses are frequently measured with an ordinal scale. To compare the efficacy of these treatments, one could employ either the proportional odds model or the latent normal model. However, these two models are inadequ
Publikováno v:
Statistical methods in medical research. 29(2)
Ordinal responses are common in clinical studies. Although the proportional odds model is a popular option for analyzing ordered-categorical data, it cannot control the type I error rate when the proportional odds assumption fails to hold. The latent
Publikováno v:
BiometricsREFERENCES. 76(1)
In long-term clinical studies, recurrent event data are sometimes collected and used to contrast the efficacies of two different treatments. The event reoccurrence rates can be compared using the popular negative binomial model, which incorporates in
Publikováno v:
Statistical methods in medical research. 27(11)
The increase in the popularity of non-inferiority clinical trials represents the increasing need to search for substitutes for some reference (standard) treatments. A new treatment would be preferred to the standard treatment if the benefits of adopt