Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sitthivut, Charoensutthivarakul"'
Autor:
Phongthon Kanjanasirirat, Witchuda Saengsawang, Pimonrat Ketsawatsomkron, Nithi Asavapanumas, Suparerk Borwornpinyo, Sunhapas Soodvilai, Suradej Hongeng, Sitthivut Charoensutthivarakul
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39343- (2024)
Blood-brain barrier (BBB) is a crucial membrane safeguarding neural tissue by controlling the molecular exchange between blood and the brain. However, assessing BBB permeability presents challenges for central nervous system (CNS) drug development. I
Externí odkaz:
https://doaj.org/article/b1084fd222ea4a389b0741271da328ba
Autor:
Orawan Jongsomjainuk, Jutatip Boonsombat, Sanit Thongnest, Hunsa Prawat, Paratchata Batsomboon, Sitthivut Charoensutthivarakul, Saroj Ruchisansakun, Kittipong Chainok, Jitnapa Sirirak, Chulabhorn Mahidol, Somsak Ruchirawat
Publikováno v:
Natural Products and Bioprospecting, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Four highly oxidized pimarane diterpenoids were isolated from Kaempferia takensis rhizomes. Kaemtakols A–C possess a tetracyclic ring with either a fused tetrahydropyran or tetrahydrofuran motif. Kaemtakol D has an unusual rearranged A/B r
Externí odkaz:
https://doaj.org/article/483fb340a7034592baf77b0ec2bfd63c
Autor:
Peeraya Ekchariyawat, Rattatammanoon Saengfak, Sucharat Sanongkiet, Thanapon Charoenwongpaiboon, Suphasuta Khongpraphan, Supaporn Mala, Chularat Luangjindarat, Bumrung Munyoo, Napason Chabang, Sitthivut Charoensutthivarakul, Suparerk Borwornpinyo, Patoomratana Tuchinda, Marisa Ponpuak, Matsayapan Pudla, Pongsak Utaisincharoen
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0292340 (2023)
BackgroundCleistanthin A (CA), extracted from Phyllanthus taxodiifolius Beille, was previously reported as a potential V-ATPase inhibitor relevant to cancer cell survival. In the present study, ECDD-S16, a derivative of cleistanthin A, was investigat
Externí odkaz:
https://doaj.org/article/fd84736aed824378830f72267bfb946f
Autor:
Tanaporn Phetruen, Sittinan Chanarat, Tavan Janvilisri, Matthew Phanchana, Sitthivut Charoensutthivarakul, Wichuda Phothichaisri, Surang Chankhamhaengdecha
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Receptor-binding proteins (RBPs) are located at the viral tail and mediate the initial recognition of phage to a specific bacterial host. Phage RBPs have co-evolved with numerous types of host receptors resulting in the formation of a diverse assortm
Externí odkaz:
https://doaj.org/article/5a1e8289e18a496fb07954a27e00eba7
Autor:
Sitthivut Charoensutthivarakul, Duangporn Lohawittayanan, Phongthon Kanjanasirirat, Kedchin Jearawuttanakul, Sawinee Seemakhan, Napason Chabang, Patrick Schlaeppi, Varisa Tantivess, Tanapol Limboonreung, Matthew Phanchana
Publikováno v:
Molecules, Vol 28, Iss 7, p 2999 (2023)
Quinazolinedione is one of the most outstanding heterocycles in medicinal chemistry thanks to its wide ranges of biological activities including antimalarial, anticancer, and anti-inflammatory. TCMDC-125133 containing a quinazolinedione pharmacophore
Externí odkaz:
https://doaj.org/article/49dc94af67644fd2a1cf5c7ce63cb96a
Autor:
Sitthivut Charoensutthivarakul, Duangporn Lohawittayanan, Phongthon Kanjanasirirat, Kedchin Jearawuttanakul, Sawinee Seemakhan, Suparerk Borwornpinyo, Matthew Phanchana
Publikováno v:
Molbank, Vol 2022, Iss 2, p M1358 (2022)
Quinazolinedione is one of the most notable pharmacophores in drug discovery due to its broad spectrum of biological activities including antimalarial, anticancer, anti-inflammatory, and others. TCMDC-125133, whose structure features a quinazolinedio
Externí odkaz:
https://doaj.org/article/3f85c6565d944e4099ec06dd4cf4a0e8
Autor:
Rachel H. Clare, Catherine Bardelle, Paul Harper, W. David Hong, Ulf Börjesson, Kelly L. Johnston, Matthew Collier, Laura Myhill, Andrew Cassidy, Darren Plant, Helen Plant, Roger Clark, Darren A. N. Cook, Andrew Steven, John Archer, Paul McGillan, Sitthivut Charoensutthivarakul, Jaclyn Bibby, Raman Sharma, Gemma L. Nixon, Barton E. Slatko, Lindsey Cantin, Bo Wu, Joseph Turner, Louise Ford, Kirsty Rich, Mark Wigglesworth, Neil G. Berry, Paul M. O’Neill, Mark J. Taylor, Stephen A. Ward
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Parasitic nematodes causing onchocerciasis and lymphatic filariasis rely on a bacterial endosymbiont, Wolbachia, which is a validated therapeutic target. Here, Clare et al. perform a high-throughput screen of 1.3 million compounds and identify 5 chem
Externí odkaz:
https://doaj.org/article/4cb4bba947a8460babf1f27b9cb22a73
Autor:
Sitthivut Charoensutthivarakul, Sherine E. Thomas, Amy Curran, Karen P. Brown, Juan M. Belardinelli, Andrew J. Whitehouse, Marta Acebrón-García-de-Eulate, Jaspar Sangan, Subramanian G. Gramani, Mary Jackson, Vitor Mendes, R. Andres Floto, Tom L. Blundell, Anthony G. Coyne, Chris Abell
Publikováno v:
ACS Infectious Diseases. 8:296-309
Autor:
Surang Chankhamhaengdecha, Wichuda Phothichaisri, Supakan Panturat, Matthew Phanchana, Sitthivut Charoensutthivarakul, Methinee Pipatthana, Tavan Janvilisri, Phurt Harnvoravongchai, Supapit Wongkuna, Tanaporn Phetruen
Publikováno v:
World Journal of Gastroenterology. 27:7210-7232
Autor:
Supasek Kongsomros, Yongyut Pewkliang, Arunee Thitithanyanont, Warawuth Wannalo, Sitthivut Charoensutthivarakul, Patompon Wongtrakoongate, Kedchin Jearawuttanakul, Jarinya Chaopreecha, Phisit Khemawoot, Suparerk Borwornpinyo, Somchai Chutipongtanate, Suwimon Manopwisedjaroen, Piyanoot Thongsri, Suradej Hongeng, Ampa Suksatu, Khanit Sa-ngiamsuntorn, Phongthon Kanjanasirirat, Supaporn Pitiporn
Publikováno v:
Journal of Natural Products. 84:1261-1270
The coronaviruses disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) has become a major health problem, affecting more than 50 million people with over one million deaths globally. Effective antivirals are still lacking. Here, we opti