Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Siti Zulaikha Nashwa Mohd Khair"'
Autor:
Siti Muslihah Ab Radzak, Siti Zulaikha Nashwa Mohd Khair, Zamzuri Idris, Wan Muhamad Amir Wan Ahmad, Azim Patar, Abdul Aziz Mohamed Yusoff
Publikováno v:
Eurasian Journal of Medicine, Vol 56, Iss 1, Pp 7-14 (2024)
Background: Investigating the role of mitochondrial DNA (mtDNA) alterations and their impact on brain tumor progression remains a significant focus in cancer research. The research aimed to explore the specific contributions of mtDNA copy number chan
Externí odkaz:
https://doaj.org/article/c7013a8c5f6241d58ed72b97b4fd4295
Autor:
Siti Zulaikha Nashwa Mohd Khair, Abdul Salim Ismail, Zunaina Embong, Abdul Aziz Mohamed Yusoff
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 14, Iss 2, Pp 171-178 (2019)
Purpose: To determine the mutational analyses of familial exudative vitreoretinopathy (FEVR)-causing genes in Malay patients with retinopathy of prematurity (ROP) to obtain preliminary data for gene alterations in the Malay community. Methods: A comp
Externí odkaz:
https://doaj.org/article/e6bb46499db747debfa9dce774a755c5
Autor:
Abdul Aziz Mohamed Yusoff, Wan Salihah Wan Abdullah, Siti Zulaikha Nashwa Mohd Khair, Siti Muslihah Abd Radzak
Publikováno v:
Oncology Reviews, Vol 13, Iss 1 (2019)
Mitochondria are cellular machines essential for energy production. The biogenesis of mitochondria is a highly complex and it depends on the coordination of the nuclear and mitochondrial genome. Mitochondrial DNA (mtDNA) mutations and deletions are s
Externí odkaz:
https://doaj.org/article/19b9195e74aa44d19183903c944d2ac5
Publikováno v:
Disease Markers, Vol 2021 (2021)
Disease Markers
Disease Markers
Cancer is a heterogeneous group of diseases, the progression of which demands an accumulation of genetic mutations and epigenetic alterations of the human nuclear genome or possibly in the mitochondrial genome as well. Despite modern diagnostic and t
Autor:
Siti Muslihah Abd Radzak, Siti Zulaikha Nashwa Mohd Khair, Wan Salihah Wan Abdullah, Abdul Aziz Mohamed Yusoff
Publikováno v:
Oncology Reviews
Oncology Reviews, Vol 13, Iss 1 (2019)
Oncology Reviews, Vol 13, Iss 1 (2019)
Mitochondria are cellular machines essential for energy production. The biogenesis of mitochondria is a highly complex and it depends on the coordination of the nuclear and mitochondrial genome. Mitochondrial DNA (mtDNA) mutations and deletions are s
Autor:
Siti Zulaikha Nashwa Mohd Khair, Siti Muslihah Abd Radzak, Wan Salihah Wan Abdullah, Abdul Aziz Mohamed Yusoff, Jafri Malin Abdullah
Publikováno v:
Journal of Cancer Research and Therapeutics. 16:1517
Background and Objective: Meningiomas are among the most common intracranial tumors of the central nervous system. It is widely accepted that the initiation and progression of meningiomas involve the accumulation of nucleus genetic alterations, but l
Autor:
Khairol Naaim Mohd Nasir, Jafri Malin Abdullah, Khalilah Haris, Abdul Rahman Izaini Ghani, Abdul Aziz Mohamed Yusoff, Zamzuri Idris, Siti Zulaikha Nashwa Mohd Khair
Publikováno v:
Oncology Letters
Although the role of nuclear-encoded gene alterations has been well documented in brain tumor development, the involvement of the mitochondrial genome in brain tumorigenesis has not yet been fully elucidated and remains controversial. The present stu
Autor:
Siti Zulaikha Nashwa Mohd Khair, Abdul Aziz Mohamed Yusoff, Wan Salihah Wan Abdullah, Fatin Najwa Zulfakhar, Jafri Malin Abdullah, Zamzuri Idris
Publikováno v:
Brain Tumor Research and Treatment
Background Mitochondria are major cellular sources of reactive oxygen species (ROS) generation which can induce mitochondrial DNA damage and lead to carcinogenesis. The mitochondrial 10398A>G alteration in NADH-dehydrogenase subunit 3 (ND3) can sever