Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Siti Mariam Zakaria"'
Autor:
Diana Cepeda, Hwee‐Fang Ng, Hamid Reza Sharifi, Salah Mahmoudi, Vanessa Soto Cerrato, Erik Fredlund, Kristina Magnusson, Helén Nilsson, Alena Malyukova, Juha Rantala, Daniel Klevebring, Francesc Viñals, Nimesh Bhaskaran, Siti Mariam Zakaria, Aldwin Suryo Rahmanto, Stefan Grotegut, Michael Lund Nielsen, Cristina Al‐Khalili Szigyarto, Dahui Sun, Mikael Lerner, Sanjay Navani, Martin Widschwendter, Mathias Uhlén, Karin Jirström, Fredrik Pontén, James Wohlschlegel, Dan Grandér, Charles Spruck, Lars‐Gunnar Larsson, Olle Sangfelt
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 7, Pp 1067-1086 (2013)
Abstract SCF (Skp1/Cul1/F‐box) ubiquitin ligases act as master regulators of cellular homeostasis by targeting key proteins for ubiquitylation. Here, we identified a hitherto uncharacterized F‐box protein, FBXO28 that controls MYC‐dependent tra
Externí odkaz:
https://doaj.org/article/5062dd7638fb498c83728c328d552d33
Autor:
Lars-Gunnar Larsson, Jiri Bartek, Madhurendra Singh, Alina Castell, Galina Selivanova, Siti Mariam Zakaria, Susanna Tronnersjö, Fan Zhang, Jacob Goodwin, Vedrana Tabor
Publikováno v:
Cell Cycle
The MYC and RAS oncogenes are sufficient for transformation of normal rodent cells. This cooperativity is at least in part based on suppression of RAS-induced cellular senescence by MYC and block of MYC-induced apoptosis by RAS – thereby canceling
Publikováno v:
Creative Education. :2107-2120
Equipping students with 21st century skills has become the main focus among educators. In line with the Ministry of Education initiatives in transforming the framework of Malaysia Education system, 11 shifts charted are steered to witness the nation
Autor:
Fan Zhang, Wesam Bazzar, Jacob Goodwin, Lars Larsson, Per Hydbring, Alina Castell, Siti Mariam Zakaria, Karin Fawkner, Giovanna Zinzalla, Qinzi Yan, Marcela Franco, Vasiliki Verschut
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports
Scientific Reports
MYC is a key player in tumor development, but unfortunately no specific MYC-targeting drugs are clinically available. MYC is strictly dependent on heterodimerization with MAX for transcription activation. Aiming at targeting this interaction, we iden
Autor:
Stefan Grotegut, Daniel Klevebring, Helen Nilsson, Dahui Sun, Sanjay Navani, Fredrik Pontén, Karin Jirström, Juha Rantala, Mikael Lerner, Michael L. Nielsen, Kristina Magnusson, Vanessa Soto Cerrato, Mathias Uhlén, Salah Mahmoudi, Aldwin Suryo Rahmanto, Martin Widschwendter, Charles Spruck, Francesc Viñals, Cristina Al-Khalili Szigyarto, Erik Fredlund, Hamid Sharifi, Dan Grandér, James A. Wohlschlegel, Diana Cepeda, Nimesh Bhaskaran, Lars-Gunnar Larsson, Olle Sangfelt, Siti Mariam Zakaria, Hwee-Fang Ng, Alena Malyukova
Publikováno v:
EMBO Molecular Medicine. 5:1067-1086
SCF (Skp1/Cul1/F-box) ubiquitin ligases act as master regulators of cellular homeostasis by targeting key proteins for ubiquitylation. Here, we identified a hitherto uncharacterized F-box protein, FBXO28 that controls MYC-dependent transcription by n
Autor:
Intan Safinar Ismail, Christian Paetz, Siti Mariam Zakaria, Khozirah Shaari, Daud Ahmad Israf, Nordin H. Lajis, Khairana Husain
Publikováno v:
Phytochemistry Letters. 5:788-792
A novel sesquiterpene, nordine (or 2,2,9-trimethyl-5-methylene-12-oxa-bicyclo[6.3.1]dodecane-4,9-diol) (1) and two new copyrine alkaloids of eupolauridine skeleton, viz., 4,11-dimethoxyeupolauridine (2) and 2-methoxy-3-hydroxyeupolauridine (3), along
Autor:
Sara Fahlén, Oliver Frings, Per Hydbring, Alina Castell, Jacob Goodwin, Siti Mariam Zakaria, Susanna Tronnersjö, Bernhard Lüscher, Fuad Bahram, Lars-Gunnar Larsson, Helén Nilsson, Natalie von der Lehr, Yingtao Su
Publikováno v:
Oncotarget
OncoTarget: open access impact journal 7(3), 2837-2854 (2015). doi:10.18632/oncotarget.6693
OncoTarget: open access impact journal 7(3), 2837-2854 (2015). doi:10.18632/oncotarget.6693
OncoTarget: open access impact journal 7(3), 2837-2854 (2015). doi:10.18632/oncotarget.6693
Published by Impact Journals LLC, [S.l.]
Published by Impact Journals LLC, [S.l.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b475e3845b3170e75f2fca37c0e00532
Autor:
Jacob Goodwin, Alina Castell, Lars-Gunnar Larsson, Inga Müller, Per Hydbring, Qinzi Yan, Fan Zhang, Siti Mariam Zakaria, Marcela Franco, Karin Ridderstråle, Lars Johansson
Publikováno v:
Cancer Research. 76:1227-1227
Deregulated expression of MYC family oncogenes MYC, MYCN and MYCL (here collectively referred to as MYC) occurs in many types of human tumors, and is often associated with aggressive tumor development and poor prognosis. In mouse tumor models, inacti