Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Siti Aishah B. Rahmat"'
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Contains primer sequences, additional materials and methods to complement main article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b37c9e65a86bcf2c28b57ce4daaf357
https://doi.org/10.1158/0008-5472.22414832
https://doi.org/10.1158/0008-5472.22414832
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Supplementary Figure S1. Related to Figure 1. Unravelling the mechanism of C646 action.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef9827e23508f52f106cc5eaf689fb3
https://doi.org/10.1158/0008-5472.22414850
https://doi.org/10.1158/0008-5472.22414850
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Supplementary Figure S2. Related to Figure 2. C646 prevents specific p53 lysines from acetylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc438d25a276852ff42cf1b2341963da
https://doi.org/10.1158/0008-5472.22414847.v1
https://doi.org/10.1158/0008-5472.22414847.v1
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Supplementary Figure S4. Related to Figure 5. C646 selectively protects human bone marrow over colorectal cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fd813d523f23f6e19d2f99b11d4829
https://doi.org/10.1158/0008-5472.22414841
https://doi.org/10.1158/0008-5472.22414841
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Supplementary Figure S5. Related to Figure 6 and 7. C646 protects bone marrow function while preserving doxorubicin efficacy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a767522c593a886407897e8508c78c25
https://doi.org/10.1158/0008-5472.22414838.v1
https://doi.org/10.1158/0008-5472.22414838.v1
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Chemotoxicity due to unwanted p53 activation in the bone marrow remains an unmet clinical challenge. Doxorubicin, a first-line chemotherapy drug, often causes myelosuppression in patients, thus limiting its effectiveness. In this study, we discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beef2ddaeff5e1cc597ebe24c809cede
https://doi.org/10.1158/0008-5472.c.6509087.v1
https://doi.org/10.1158/0008-5472.c.6509087.v1
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Contain Legends for Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f517a296f5b6bac022847556ac4deb
https://doi.org/10.1158/0008-5472.22414835
https://doi.org/10.1158/0008-5472.22414835
Autor:
David P. Lane, Le-Ann Hwang, Siti Aishah B. Rahmat, Hui Chin Goh, Xin Yu Koh, Shunsheng Zheng
Supplementary Figure S3. Related to Figure 3. C646 reduces the stabilization of p53 protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a24cc52e560372822cd5b43f063296
https://doi.org/10.1158/0008-5472.22414844
https://doi.org/10.1158/0008-5472.22414844