Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Siti A B Aman"'
Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice
Autor:
Abhay P. S. Rathore, Chinmay K. Mantri, Meredith W. Tan, Roksana Shirazi, Andrew Nishida, Siti A. B. Aman, Juliet Morrison, Ashley L. St. John
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dengue virus (DENV), a Flavivirus, causes a broad spectrum of disease in humans with key clinical signs including thrombocytopenia, vascular leakage and hemorrhaging. A major obstacle to understanding DENV immunity has been the lack of a validated im
Externí odkaz:
https://doaj.org/article/978a3be9651448bf870e8cf25f7fae73
Autor:
Harsha Dissanayake, C Punchihewa, Chandima Jeewandara, Ashley L. St. John, Samitha Fernando, Damayanthi Idampitiya, Graham S. Ogg, Supun Samarasekara, Gathsaurie Neelika Malavige, Siti A B Aman, Anushka Ginneliya, S. A. Paranavitane, Ananda Wijewickrama, Praveen Madushanka, Shamini Prathapan, Chandanie Wanigatunga, Laksiri Gomes
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
Currently there are no specific treatments available for acute dengue infection. We considered that rupatadine, a platelet-activating factor receptor inhibitor, might modulate dengue-associated vascular leak. The effects of rupatadine were assessed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12df27d3ffa3d514df7ded02cb448b5
http://link.springer.com/article/10.1038/s41598-018-22285-x
http://link.springer.com/article/10.1038/s41598-018-22285-x
Autor:
Siti A B Aman, Andrew Nishida, Chinmay K. Mantri, Ashley L. St. John, Juliet Morrison, Abhay P. S. Rathore
Publikováno v:
Journal of virology, vol 91, iss 18
Journal of Virology
Journal of Virology
There are no approved therapeutics for the treatment of dengue disease despite the global prevalence of dengue virus (DENV) and its mosquito vectors. DENV infections can lead to vascular complications, hemorrhage, and shock due to the ability of DENV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbca8f8ea24f5aa66fa41680c3fa30a
https://escholarship.org/uc/item/1vs317th
https://escholarship.org/uc/item/1vs317th
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
Dengue virus (DENV) is the most significant human arboviral pathogen and causes ∼400 million infections in humans each year. In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f09282f66994b099ec22cd991bf538
https://pubmed.ncbi.nlm.nih.gov/25783751
https://pubmed.ncbi.nlm.nih.gov/25783751
Autor:
Sylvie Alonso, Ashley L. St. John, Julia María Martínez Gómez, Jian Hang Lam, Siti A B Aman, Eshele Anak Libau, Pei Xuan Lee, Li Ching Ong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 3, p e0004536 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Epidemiological studies have reported that most of the severe dengue cases occur upon a secondary heterologous infection. Furthermore, babies born to dengue immune mothers are at greater risk of developing severe disease upon primary infection with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fb9f8c92d2ba37743120de894f84c8
https://doi.org/10.1371/journal.pntd.0004536
https://doi.org/10.1371/journal.pntd.0004536