Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sithara Raju Ponny"'
Autor:
Babunageswararao Kanuri, Vincent Fong, Sithara Raju Ponny, Keri A. Tallman, Sriganesh Ramachandra Rao, Ned Porter, Steven J. Fliesler, Shailendra B. Patel
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100002- (2021)
Smith-Lemli-Opitz Syndrome (SLOS) is a developmental disorder (OMIM #270400) caused by autosomal recessive mutations in the Dhcr7 gene, which encodes the enzyme 3β-hydroxysterol-Δ7 reductase. SLOS patients present clinically with dysmorphology and
Externí odkaz:
https://doaj.org/article/fffd503a6747449ba298d727bfc30580
Autor:
Babunageswararao Kanuri, Vincent Fong, Sithara Raju Ponny, Ranjuna Weerasekera, Kirthi Pulakanti, Kriya S. Patel, Roman Tyshynsky, Shailendra B. Patel
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100028- (2021)
Abstract: The enzyme 3β-hydroxysterol-Δ24 reductase (DHCR24, EC 1.3.1.72) catalyzes the conversion of desmosterol to cholesterol and is obligatory for post-squalene cholesterol synthesis. Genetic loss of this enzyme results in desmosterolosis (MIM
Externí odkaz:
https://doaj.org/article/affc4e2d0be140319b04dd1cc9bf0b9d
Autor:
Maria P. Ivshina, Heleen M. van 't Spijker, Suna Jung, Sithara Raju Ponny, Dorothy P. Schafer, Joel D. Richter
Publikováno v:
Glia. 70:1850-1863
Microglia are myeloid cells of the central nervous system that perform tasks essential for brain development, neural circuit homeostasis, and neural disease. Microglia react to inflammatory stimuli by upregulating inflammatory signaling through sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb5b211d57037d1e4f8a407d64f68a3
https://doi.org/10.1002/glia.24222
https://doi.org/10.1002/glia.24222
Autor:
Zeynep Itah, Shanzah Chaudhry, Sithara Raju Ponny, Ozkan Aydemir, Alexandra Lee, Julie Cavanagh-Kyros, Cathy Tournier, William J. Muller, Roger J. Davis
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The HER2 + subtype of human breast cancer is associated with the malignant transformation of luminal ductal cells of the mammary epithelium. The sequence analysis of tumor DNA identifies loss of function mutations and deletions of the MAP2 K4 and MAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0431d0bd72a5d2fcb6a677b7955786af
https://doi.org/10.1073/pnas.2218373120
https://doi.org/10.1073/pnas.2218373120
Autor:
Christina M. Alfieri, Emma J Agnew, Sithara Raju Ponny, Farhan Zafar, Kyle W. Riggs, Katherine E. Yutzey, Nivedhitha Velayutham, Richard Baker
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ec53fa6149e7f52b0925e8d2e75cba
https://doi.org/10.1096/fasebj.2021.35.s1.03211
https://doi.org/10.1096/fasebj.2021.35.s1.03211
Autor:
Roman Tyshynsky, Shailendra B. Patel, Sithara Raju Ponny, Kirthi Pulakanti, Babu Nageswararao Kanuri, Ranjuna Weerasekera, Kriya S. Patel, Vincent Fong
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100028-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100028-(2021)
The enzyme 3β-hydroxysterol-Δ24 reductase (DHCR24, EC 1.3.1.72) catalyzes the conversion of desmosterol to cholesterol and is obligatory for post-squalene cholesterol synthesis. Genetic loss of this enzyme results in desmosterolosis (MIM #602398),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07891d6a4a13061ce051312bb0c74109
http://europepmc.org/articles/PMC7933790
http://europepmc.org/articles/PMC7933790
Autor:
Steven J. Fliesler, Sriganesh Ramachandra Rao, Sithara Raju Ponny, Ned A. Porter, Shailendra B. Patel, Vincent Fong, Babu Nageswararao Kanuri, Keri A. Tallman
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100002-(2021)
Journal of Lipid Research
Journal of Lipid Research
Smith-Lemli-Opitz Syndrome (SLOS) is a developmental disorder (OMIM #270400) caused by autosomal recessive mutations in the Dhcr7 gene, which encodes the enzyme 3β-hydroxysterol-Δ7 reductase. SLOS patients present clinically with dysmorphology and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628669fe15a4d77e5ef7fd0fbdf15f34
http://www.sciencedirect.com/science/article/pii/S0022227520437046
http://www.sciencedirect.com/science/article/pii/S0022227520437046
Autor:
Farhan Zafar, Emma J Agnew, Christina M. Alfieri, Kyle W. Riggs, Nivedhitha Velayutham, Katherine E. Yutzey, Sithara Raju Ponny, Richard S Baker
Publikováno v:
Circulation. 142
Background: Rodent cardiomyocytes (CM) undergo mitotic arrest and decline of mononucleated-diploid population post-birth, which are implicated in neonatal loss of heart regenerative potential. However, the dynamics of postnatal CM maturation are larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01153abe24d55f66738137d9a9ac3fcb
https://doi.org/10.1161/circ.142.suppl_3.13391
https://doi.org/10.1161/circ.142.suppl_3.13391
Autor:
Alexia Hulin, Andrew J. Kim, Kazuhiro Umeyama, Bruce M. McManus, Na Xu, Katherine E. Yutzey, Paul J. Hanson, Hiroshi Nagashima, Ellis A. Green, Sithara Raju Ponny, Ronald J. Vagnozzi
Publikováno v:
Circulation
Background: Myxomatous valve degeneration (MVD) involves the progressive thickening and degeneration of the heart valves, leading to valve prolapse, regurgitant blood flow, and impaired cardiac function. Leukocytes composed primarily of macrophages h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b16da9adc454579f475f033b45e9cc3
https://pubmed.ncbi.nlm.nih.gov/31928435
https://pubmed.ncbi.nlm.nih.gov/31928435
Autor:
Paul M. Weinberger, Sithara Raju Ponny, Shan Bai, Ashok Sharma, John A. Copland, Robert C. Smallridge, Hongyan Xu
Publikováno v:
Thyroid. 27:236-252
Anaplastic thyroid carcinoma (ATC) accounts for only 3% of thyroid cancers, yet strikingly, it accounts for almost 40% of thyroid cancer deaths. Currently, no effective therapies exist. In an effort to identify ATC-specific therapeutic targets, we an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ac7180e8e4dcca5b5e456e69aac64e
https://doi.org/10.1089/thy.2016.0285
https://doi.org/10.1089/thy.2016.0285