Zobrazeno 1 - 10
of 5 587
pro vyhledávání: '"Site-Specific Recombination"'
Autor:
Alasdair I. MacDonald, Aron Baksh, Alexandria Holland, Heewhan Shin, Phoebe A. Rice, W. Marshall Stark, Femi J. Olorunniji
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Serine integrases are phage- (or mobile element-) encoded enzymes that catalyse site-specific recombination reactions between a short DNA sequence on the phage genome (attP) and a corresponding host genome sequence (attB), thereby integratin
Externí odkaz:
https://doaj.org/article/73b6640b58ef469a864e4d5cbc87a337
Akademický článek
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Autor:
Lukas Theo Schmitt, Aksana Schneider, Jonas Posorski, Felix Lansing, Milica Jelicic, Manavi Jain, Shady Sayed, Frank Buchholz, Duran Sürün
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract We introduce DEQSeq, a nanopore sequencing approach that rationalizes the selection of favorable genome editing enzymes from directed molecular evolution experiments. With the ability to capture full-length sequences, editing efficiencies, a
Externí odkaz:
https://doaj.org/article/c69155717f2d4c8d8cd7c4d0154a583c
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionOver the past decade, Corynebacterium striatum (C. striatum), an emerging multidrug-resistant (MDR) pathogen, has significantly challenged healthcare settings, especially those involving individuals with weakened immune systems. The rise
Externí odkaz:
https://doaj.org/article/ddd869bcc89b4c09bf04ed2f0a254b26
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
During the development of traditional Chinese hamster ovary (CHO) cell lines, target genes randomly integrate into the genome upon entering the nucleus, resulting in unpredictable productivity of cell clones. The characterization and screening of hig
Externí odkaz:
https://doaj.org/article/4f0056a0b19c42bf8787615c609ce445
Autor:
Chunhui Xu, James A. Birchler
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/5b313d3a8e384a1899168cbc1afa0d59
Akademický článek
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Autor:
Ke Liu, Gui-Hong Lin, Kun Liu, Yong-Jun Liu, Xin-Yi Tao, Bei Gao, Ming Zhao, Dong-Zhi Wei, Feng-Qing Wang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 3, Pp 1002-1011 (2022)
Genomic integration of genes and pathway-sized DNA cassettes is often an indispensable way to construct robust and productive microbial cell factories. For some uncommon microbial hosts, such as Mycolicibacterium and Mycobacterium species, however, i
Externí odkaz:
https://doaj.org/article/f163570f81b741788043595dadd0bd52
Autor:
Constanze Gummelt, Susann Dupke, Sabine Howaldt, Fee Zimmermann, Holger C. Scholz, Michael Laue, Silke R. Klee
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1442 (2023)
Bacillus cereus biovar anthracis (Bcbva) is an untypical pathogen causing a fatal anthrax-like disease in a variety of wildlife species in African rainforest areas. In contrast to Bacillus anthracis and most species of the B. cereus group, all strain
Externí odkaz:
https://doaj.org/article/2cd467a8fb1b4739a11d92f271844096
Autor:
Lucía Giacone, M. Marcela Cameranesi, Rocío I. Sanchez, Adriana S. Limansky, Jorgelina Morán-Barrio, Alejandro M. Viale
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The acquisition of blaOXA genes encoding different carbapenem-hydrolyzing class-D β-lactamases (CHDL) represents a main determinant of carbapenem resistance in the nosocomial pathogen Acinetobacter baumannii. The blaOXA-58 gene, in particular, is ge
Externí odkaz:
https://doaj.org/article/9851cbf1a6444535a494307c1b1128ea