Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Sitarik P"'
Autor:
Germaine J. M. Yong, Cara E. Porsche, Alexandra R. Sitarik, Kei E. Fujimura, Kathryn McCauley, Dat T. Nguyen, Albert M. Levin, Kimberley J. Woodcroft, Dennis R. Ownby, Andrew G. Rundle, Christine C. Johnson, Andrea Cassidy-Bushrow, Susan V. Lynch
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTEarly life gut microbiome composition has been correlated with childhood obesity, though microbial functional contributions to disease origins remain unclear. Here, using an infant birth cohort (n = 349) we identify a distinct fecal microbiot
Externí odkaz:
https://doaj.org/article/03d3632a2e5a42ce9c7a4123c0dc23ae
Autor:
Ritaban Halder, Daniel A. Nissley, Ian Sitarik, Yang Jiang, Yiyun Rao, Quyen V. Vu, Mai Suan Li, Justin Pritchard, Edward P. O’Brien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Subpopulations of soluble, misfolded proteins can bypass chaperones within cells. The extent of this phenomenon and how it happens at the molecular level are unknown. Through a meta-analysis of the experimental literature we find that in all
Externí odkaz:
https://doaj.org/article/28cea423dcfb4f54aedae0157fc7f68b
Autor:
Ghassan Allo, Alexandra R Sitarik, Ashley Redding, Chad M Coleman, Andrea E Cassidy-Bushrow, Arthur Gaba, Jennifer K Straughen
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302682 (2024)
IntroductionThe impact of COVID-19 on the placenta is poorly described, particularly among minority women.Materials and methodsThis is a retrospective case-control study. Micro- and macroscopic placental pathologic findings were compared for 15 COVID
Externí odkaz:
https://doaj.org/article/452ac970d6a742c9a9e90c3c3d5b0548
Akademický článek
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Autor:
Jennifer K. Straughen, Alexandra R. Sitarik, A. Daniel Jones, Jia Li, Ghassan Allo, Carolyn Salafia, Andrea E. Cassidy-Bushrow, Nigel Paneth
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Methods for collection of placental tissue at room temperature for metabolic profiling are described. Specimens were excised from the maternal side of the placenta and immediately flash frozen or fixed and stored for 1, 6, 12, 24, or 48 h in
Externí odkaz:
https://doaj.org/article/94bb9a70db0b47baa3190911752818e1
Akademický článek
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Autor:
Elizabeth K Mallott, Alexandra R Sitarik, Leslie D Leve, Camille Cioffi, Carlos A Camargo, Kohei Hasegawa, Seth R Bordenstein
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002230 (2023)
Human microbiome variation is linked to the incidence, prevalence, and mortality of many diseases and associates with race and ethnicity in the United States. However, the age at which microbiome variability emerges between these groups remains a cen
Externí odkaz:
https://doaj.org/article/fbd938a93c254421a413a0f8098010f2
Autor:
Yuhang Wu, Samadhan S. Nagane, Quintin Baugh, Chun-Yuan Lo, Shrirang S. Chhatre, Junghyun Lee, Peter Sitarik, Laure V. Kayser, David C. Martin
Publikováno v:
Giant, Vol 15, Iss , Pp 100163- (2023)
Cholesterol is a rigid, crystalline, non-polar natural substance that exists in animal blood and cell membranes. Some of its derivatives are known to form ordered liquid crystalline mesophases under suitable conditions. In this work, we carefully exa
Externí odkaz:
https://doaj.org/article/fa82156d48d34536b7892f0ed5d16eea
Autor:
Alexandra R. Sitarik, Christine C. Johnson, Albert M. Levin, Susan V. Lynch, Dennis R. Ownby, Andrew G. Rundle, Jennifer K. Straughen, Ganesa Wegienka, Kimberley J. Woodcroft, Andrea E. Cassidy-Bushrow
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionDelivery via caesarean section (C-section) has been associated with an increased risk of childhood chronic diseases such as obesity and asthma, which may be due to underlying systemic inflammation. However, the impact of specific C-sectio
Externí odkaz:
https://doaj.org/article/ac3b8aec9b6245e29d47b252e8f3f1a4
Autor:
Daniel A. Nissley, Yang Jiang, Fabio Trovato, Ian Sitarik, Karthik B. Narayan, Philip To, Yingzi Xia, Stephen D. Fried, Edward P. O’Brien
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Nissley and co-workers predict protein misfolding into kinetically trapped, entangled conformations that can bypass the proteostasis network to remain soluble but less-functional for long timescales is widespread within the E. coli proteome.
Externí odkaz:
https://doaj.org/article/55213c6dc1714a15a02325661af2e402