Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sitao Xie"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The role of normal gut microbiota in asthma or ovalbumin (OVA)-induced asthma tolerance (OT) remains unclear. Here, we established mouse models of asthma and OT followed by 2 weeks of antibiotic treatment, to clear the gut microbiota. Antibiotic trea
Externí odkaz:
https://doaj.org/article/3954e003c3f649d793f25fda83d165e1
Autor:
Sitao Xie, Yulin Du, Yu Zhang, Zhimin Wang, Dailiang Zhang, Lei He, Liping Qiu, Jianhui Jiang, Weihong Tan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Optogenetic manipulation of protein localisation in cells involves the creation of fusions that can influence activity. Here the authors develop a near-infrared light-responsive aptamer-based system to regulate the nuclear-cytoplasmic shuttling of NF
Externí odkaz:
https://doaj.org/article/742312874b8542a78c33a7f1a79ba1ad
Publikováno v:
Journal of the American Chemical Society. 145:7677-7691
Publikováno v:
ACS Nano. 17:6150-6164
Autor:
Shujuan Xu, Lei He, Fengming Chen, Wenya Dang, Sitao Xie, Long Li, Cheng Cui, Yu Yang, Yanlan Liu, Weihong Tan
Publikováno v:
Chemical Communications. 59:4790-4793
A bioinspired “point-and-shoot” molecular strategy is reported to construct noncovalent bivalent aptamers with enhanced stability and binding ability mediated by a K+-induced reassembly mechanism.
Autor:
Jing Zhang, Dan Wang, Hong Chen, Xi Yuan, Xinyi Jiang, Lili Ai, Jiaxuan He, Fengming Chen, Sitao Xie, Cheng Cui, Weihong Tan
Publikováno v:
Nano Letters. 22:9441-9449
Approaches to DNA probe-mediated precision medicine have been extensively explored for the diagnosis and treatment of diverse types of cancer. Despite this, simple nanoscale devices with the required recognition specificity and sensitivity for clinic
Publikováno v:
Nano Letters. 22:7853-7859
The capacity to regulate the signaling amplitude of membrane receptors in a user-defined manner would open various opportunities for precise biological study and therapy. While partial agonists enabled downtuning of cellular responses, they required
Autor:
Zhen Du, Xin Wang, Xiao Zhang, Zhanjun Gu, Xiaoyi Fu, Shaoju Gan, Ting Fu, Sitao Xie, Weihong Tan
Publikováno v:
Angewandte Chemie. 135
Autor:
Ruowen Wang, Xueqiang Wang, Sitao Xie, Yanyan Zhang, Dingkun Ji, Xiaobing Zhang, Cheng Cui, Jianhui Jiang, Weihong Tan
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 378
Classically, a molecular element (ME) is a pure substance composed of two or more atoms of the same element. However, MEs, in the context of this review, can be any molecules as elements bonded together into the backbone of synthetic oligonucleotides
Autor:
Yiheng Chen, Derong Kong, Liping Qiu, Yungen Wu, Changhao Dai, Shi Luo, Zhipeng Huang, Qiuyuan Lin, Hui Chen, Sitao Xie, Li Geng, Jun Zhao, Weihong Tan, Yunqi Liu, Dacheng Wei
Publikováno v:
Analytical chemistry.
An aptamer-based field-effect transistor (Apta-FET) is a well-developed assay method with high selectivity and sensitivity. Due to the limited information density that natural nucleotide library holds, the Apta-FET faces fundamental restriction in un