Out-of-Hospital Cervical Ripening With a Synthetic Hygroscopic Cervical Dilator May Reduce Hospital Costs and Cesarean Sections in the United States—A Cost-Consequence Analysis

Autor: Sita J. Saunders, Rhodri Saunders, Tess Wong, Antonio F. Saad

Publikováno v: Frontiers in Public Health, Vol 9 (2021)

Objective: Out-of-hospital (outpatient) cervical ripening prior to induction of labor (IOL) is discussed for its potential to decrease the burden on hospital resources. We assessed the cost and clinical outcomes of adopting an outpatient strategy wit

Externí odkaz: https://doaj.org/article/953c09595cbb4694a7a4c4c9910ad5a3

Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model

Autor: Kate F, Walker, Summia, Zaher, Rafael, Torrejon Torres, Sita J, Saunders, Rhodri, Saunders, Janesh K, Gupta

Publikováno v: European Journal of Obstetrics & Gynecology and Reproductive Biology. 278:72-76

To estimate the costs of synthetic osmotic dilators (Dilapan-S) compared to dinoprostone vaginal inserts (Propess) for inpatient induction of labour (IOL).A population-level, Markov model-based cost-consequence analysis was developed to compare the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cf3983f89d89e250f39c2cc4ca6b7e
https://doi.org/10.1016/j.ejogrb.2022.08.018

Critical Review of European Health-Economic Guidelines for the Health Technology Assessment of Medical Devices

Autor: Rafael Torrejon Torres, Maximilian Blüher, Virginie Mittard, Sita J. Saunders, Rhodri Saunders, Jason A. Davis

Publikováno v: Frontiers in Medicine, Vol 6 (2019)
Frontiers in Medicine

Background: Health-technology assessment (HTA) is a recognized mechanism to determine the relative benefits of innovative medical technologies. One aspect is their health-economic impact. While the process and methodology for pharmaceuticals is well-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc783769e4c1a116532477d38be5b79
https://doi.org/10.3389/fmed.2019.00278

Characterizing leader sequences of CRISPR loci

Autor: Rolf Backofen, Fabrizio Costa, Omer S. Alkhnbashi, Shiraz A. Shah, Sita J. Saunders, Roger A. Garrett

Publikováno v: Bioinformatics. 32:i576-i585

Motivation The CRISPR-Cas system is an adaptive immune system in many archaea and bacteria, which provides resistance against invading genetic elements. The first phase of CRISPR-Cas immunity is called adaptation, in which small DNA fragments are exc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6094638bb98ed6ad9b7742d3802a213a
https://doi.org/10.1093/bioinformatics/btw454

CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci

Autor: Fabrizio Costa, Roger A. Garrett, Omer S. Alkhnbashi, Shiraz A. Shah, Sita J. Saunders, Rolf Backofen

Publikováno v: Bioinformatics
Alkhnbashi, O S, Costa, F, Shah, S A, Garrett, R A, Saunders, S J & Backofen, R 2014, ' CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci ', Bioinformatics, vol. 30, no. 17, pp. i489-i496 . https://doi.org/10.1093/bioinformatics/btu459

Motivation: The discovery of CRISPR-Cas systems almost 20 years ago rapidly changed our perception of the bacterial and archaeal immune systems. CRISPR loci consist of several repetitive DNA sequences called repeats, inter-spaced by stretches of vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8d189494356cce3f93b8c473e0a15b
http://europepmc.org/articles/PMC4147912