Výsledky vyhledávání - "Sissy Therese, Sonnleitner"

Akademický článek

Omicron (B.1.1.529) BA.1 or BA.2-related effects on immune responses in previously naïve versus imprinted individuals: immune imprinting as an advantage in the humoral immune response against novel variants

Autor: Sissy Therese Sonnleitner, Samira Walder, Ludwig Knabl, Roswitha Poernbacher, Thomas Tschurtschenthaler, Eva Hinterbichler, Stefanie Sonnleitner, Viktoria Muehlmann, Wilfried Posch, Gernot Walder

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundImmune imprinting is a phenomenon in which a person's immune system develops a specific immunological memory of the pathogen or vaccine due to a previous exposure. This memory basically leads to a faster and stronger immune response in a su

Externí odkaz: https://doaj.org/article/d7a8cfb1fb6148ba9382f6ab17d65081

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Akademický článek

Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host

Autor: Sissy Therese Sonnleitner, Martina Prelog, Stefanie Sonnleitner, Eva Hinterbichler, Hannah Halbfurter, Dominik B. C. Kopecky, Giovanni Almanzar, Stephan Koblmüller, Christian Sturmbauer, Leonard Feist, Ralf Horres, Wilfried Posch, Gernot Walder

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Variants of concerns arise from SARS-CoV-2 mutations poise as severe public health threats. Here the authors chronicle SARS-CoV-2 mutations onset and immune parameters in an immunocompromised patient with continuous virus-shedding, thereby hinting po

Externí odkaz: https://doaj.org/article/01c88be91c6943d8a07b2d6365ad7cd1

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Akademický článek

Immune Responses Against SARS-CoV-2 WT and Delta Variant in Elderly BNT162b2 Vaccinees

Autor: Michael Jäger, Sissy Therese Sonnleitner, Stefanie Dichtl, Eliott Lafon, Gabriel Diem, Gernot Walder, Cornelia Lass-Flörl, Doris Wilflingseder, Wilfried Posch

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

BackgroundResidents of nursing homes are one of the most vulnerable groups during the severe acute syndrome coronavirus 2 (SARS-CoV-2) pandemic. The aim of this study was to characterize cellular and humoral immune responses in >70-year-old participa

Externí odkaz: https://doaj.org/article/9030134832484f94bbe519eddb0c8f00

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The mutational dynamics of the SARS-CoV-2 virus in serial passages in vitro

Autor: Sissy Therese Sonnleitner, Stefanie Sonnleitner, Eva Hinterbichler, Hannah Halbfurter, Dominik B.C. Kopecky, Stephan Koblmüller, Christian Sturmbauer, Wilfried Posch, Gernot Walder

Publikováno v: Virologica Sinica

Since its outbreak in 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) keeps surprising the medical community by evolving diverse immune escape mutations in a rapid and effective manner. To gain deeper insight into mutation frequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba692de498ffcf7bcccd65721b525894
https://doi.org/10.1016/j.virs.2022.01.029

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Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host

Publikováno v: Nature communications. 13(1)

Different scenarios explaining the emergence of novel variants of concern (VOC) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported, including their evolution in scarcely monitored populations, in animals as alterna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f658160b2d5db1b75270f101f3d25e2e
https://pubmed.ncbi.nlm.nih.gov/35538074

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Maintenance of neutralizing antibodies over ten months in convalescent SARS‐CoV‐2 afflicted patients

Autor: Norbert Nowotny, Christian Sturmbauer, Chantal Rodgarkia-Dara, Stephan Koblmüller, Carmen Schönegger, Alexander Tichy, Sarah Gietl, Tom Loney, Hanna Jury, Bianca Jansen, Martina Prelog, Gernot Walder, Giovanni Almanzar, Wilfried Posch, Sissy Therese Sonnleitner

Publikováno v: Transboundary and Emerging Diseases

Knowledge of the level and duration of protective immunity against SARS‐CoV‐2 after primary infection is of crucial importance for preventive approaches. Currently, there is a lack of evidence on the persistence of specific antibodies. We investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48e3c9a19dfa1ff28fa503d2dc6bc11
http://europepmc.org/articles/PMC8242897

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An in vitro model for assessment of SARS-CoV-2 infectivity by defining the correlation between virus isolation and quantitative PCR value: isolation success of SARS-CoV-2 from oropharyngeal swabs correlates negatively with Cq value

Autor: Christian Sturmbauer, Stephan Koblmüller, Sarah Gietl, Sissy Therese Sonnleitner, Gernot Walder, Wilfried Posch, Carmen Schönegger, Bianca Jansen, Julian Dorighi

Publikováno v: Virology Journal, Vol 18, Iss 1, Pp 1-7 (2021)
Virology Journal

Background At the beginning of the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), little was known about its actual rate of infectivity and any COVID-19 patient positive in laboratory testing was supposed to be highl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32eb851f57286cbec8793e7435f120af
https://doi.org/10.1186/s12985-021-01542-y

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