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Autor:
Jolanda P. Vermeulen, Harry van Steeg, Piet W. Wester, Rudolf B. Beems, Jan van Benthem, Joseph G. Vos, Siska Gielis, Annemieke de Vries, Conny Th. M. van Oostrom, Esther M. Hoogervorst
Publikováno v:
Cancer Research. 64:5118-5126
Both nucleotide excision repair (NER) and the p53 tumor suppressor protein play crucial roles in the prevention of cells becoming cancerous. This is clearly demonstrated by the fact that NER-deficient xeroderma pigmentosum patients and Li-Fraumeni pa