Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sisi Marcondes"'
Autor:
Ana C. Antunes Naime, Pedro H. L. Bonfitto, Carolina Solon, Maria Elisa Lopes-Pires, Gabriel F. Anhê, Edson Antunes, Sisi Marcondes
Publikováno v:
Platelets, Vol 30, Iss 8, Pp 1047-1052 (2019)
Increased reactive oxygen species (ROS) production leads to tissue damage observed in sepsis and lipopolysaccharide (LPS)-exposed animals. LPS stimulates cytokines releasing, including tumor necrosis factor alpha (TNF-α), that is important to ROS pr
Externí odkaz:
https://doaj.org/article/65f934e5a45e4e67bdff7c9946b4b6cb
Autor:
Leandro Augusto Rosseto, Maria Elisa Lopes Pires, Aylime Castanho Bolognesi Melchior, Priscila Longhin Bosquesi, Aline Renata Pavan, Sisi Marcondes, Man Chin Chung, Jean Leandro dos Santos
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 18185-18200 (2015)
Thrombosis is the main outcome of many cardiovascular diseases. Current treatments to prevent thrombotic events involve the long-term use of antiplatelet drugs. However, this therapy has several limitations, thereby justifying the development of new
Externí odkaz:
https://doaj.org/article/a2db657dc6bb4d2f83d64b2875ca34d9
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186981 (2017)
Lipopolysaccharide (LPS) from the cell envelope of Gram-negative bacteria is a principal cause of the symptoms of sepsis. LPS has been reported to modulate the function of platelets although the underlying mechanisms of LPS action in these cells rema
Externí odkaz:
https://doaj.org/article/390c4e67a56a4a64a51441b040ba11df
Autor:
M Elisa Lopes-Pires, Ana C Antunes Naime, Nádia J Almeida Cardelli, Débora J Anjos, Edson Antunes, Sisi Marcondes
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137901 (2015)
Sepsis severity has been positively correlated with platelet dysfunction, which may be due to elevations in nitric oxide (NO) and cGMP levels. Protein kinase C, Src kinases, PI3K and AKT modulate platelet activity in physiological conditions, but no
Externí odkaz:
https://doaj.org/article/e815abb5c9fc44528c2ff7a11e4a3973
Autor:
Camila B Mendes-Silverio, Luiz O S Leiria, Rafael P Morganti, Gabriel F Anhê, Sisi Marcondes, Fabíola Z Mónica, Gilberto De Nucci, Edson Antunes
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47223 (2012)
Background and aimsNitric oxide-independent soluble guanylyl cyclase (sGC) activators reactivate the haem-oxidized enzyme in vascular diseases. This study was undertaken to investigate the anti-platelet mechanisms of the haem-independent sGC activato
Externí odkaz:
https://doaj.org/article/518b0629fd4b4823871dcd9188f75a26
Autor:
Isabela Junqueira Oliveira, Sisi Marcondes, Karina Pereira Barbieri, Iracilda Zeppone Carlos, Diego Eidy Chiba, ManChin Chung, Rafael Consolin Chelucci, Jean Leandro dos Santos, Maria Elisa Lopes-Pires, Marisa Campos Polesi
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2019-10-06T15:44:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-01 Sickle Cell Anemia (SCA) is one of the most prevalent hereditary hematological diseases worldwide. The disease is characterized by chronic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad368a46a127367e180b092e12dd8c85
https://doi.org/10.1007/s00044-019-02371-z
https://doi.org/10.1007/s00044-019-02371-z
Autor:
Sisi Marcondes, Nádia J. Almeida Cardelli, M. Elisa Lopes-Pires, Edson Antunes, Pedro H.L. Bonfitto, Heloisa H. Ferreira
Publikováno v:
Life Sciences. 172:2-7
Aims Cross-talk between platelets and lymphocytes may play a role in different pathological conditions like sepsis. This study aimed to investigate the effect of lymphocytes on platelet aggregation in lipopolysaccharide (LPS)-stimulated and non-stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8a5e35114f7f3eddca8a3ca4181f14
https://doi.org/10.1016/j.lfs.2016.12.013
https://doi.org/10.1016/j.lfs.2016.12.013
Autor:
Konstantin Chegaev, Fernando Ferreira Costa, Chutima Kumkhaek, Ticiana Sidorenko de Oliveira Capote, Jean Leandro dos Santos, Roberta Fruttero, Thais Regina Ferreira de Melo, Man Chin Chung, Rafael Consolin Chelucci, Carolina Lanaro, Karina Pereira Barbieri, Iracilda Zeppone Carlos, Griffin P. Rodgers, Guilherme Felipe dos Santos Fernandes, Fernanda Coelho, Sisi Marcondes, Maria Elisa Lopes Pires, Stefano Guglielmo
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2018-12-11T17:37:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-25 N-oxide derivatives 5(a-b), 8(a-b), and 11(a-c) were designed, synthesized and evaluated in vitro and in vivo as potential drugs that are abl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa67192e62d6598f778912b5ba9c54e5
Autor:
Sisi Marcondes, Pedro H.L. Bonfitto, Edson Antunes, Ana C. Antunes Naime, M. Elisa Lopes-Pires, Roger F. Castilho, Gisele Goulart, Paulo I. Bueno, Camila B. Mendes-Silverio
Publikováno v:
Thrombosis research. 172
Introduction Tumor necrosis factor-alpha (TNF-α) exerts a critical role in inflammatory events through two distinct receptors, TNFR1 and TNFR2. Platelets have been recognized as important inflammatory cells, but little is known about the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c7facb62620849fd12f89cd19ecda1
https://pubmed.ncbi.nlm.nih.gov/30359790
https://pubmed.ncbi.nlm.nih.gov/30359790
Autor:
Maria E, Lopes Pires, Ana C, Antunes Naime, Jessica G F, Oliveira, Gabriel F, Anhe, Oliver, Garraud, Fabrice, Cognasse, Edson, Antunes, Sisi, Marcondes
Publikováno v:
Basicclinical pharmacologytoxicology. 124(4)
Thrombocytopenia during sepsis is associated with a less favourable clinical outcome. Overproduction of reactive oxygen species (ROS) by different cell types contributes to sepsis. Platelets generate ROS, but the upstream pathways of NADPH oxidase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4250bf550722b92ca125a3b7129c5827
https://pubmed.ncbi.nlm.nih.gov/30318767
https://pubmed.ncbi.nlm.nih.gov/30318767