Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sirpa Jylhä"'
Autor:
Juha Rouvinen, Janne Jänis, Marja-Leena Laukkanen, Sirpa Jylhä, Merja Niemi, Tero Päivinen, Soili Mäkinen-Kiljunen, Tari Haahtela, Hans Söderlund, Kristiina Takkinen
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9037 (2010)
BACKGROUND: Allergen-mediated cross-linking of IgE antibodies bound to the FcepsilonRI receptors on the mast cell surface is the key feature of the type I allergy. If an allergen is a homodimer, its allergenicity is enhanced because it would only nee
Externí odkaz:
https://doaj.org/article/bf361d98e4f645daaf31a70b18ba8588
Autor:
Riikka Kietäväinen, Pauliina Rajala, Merja Itävaara, Carmen Höschen, Lotta Purkamo, Sirpa Jylhä, Carsten W. Mueller, Malin Bomberg, Mari Raulio, Lasse Ahonen
Publikováno v:
AIMS Microbiology. 3:846-871
Microbial communities in deep subsurface environments comprise a large portion of Earth’s biomass, but the metabolic activities in these habitats are largely unknown. Here the effect of CO2 and carbonate on the microbial community of an isolated gr
Autor:
Trine Kastrup Dalsgaard, Leo H. de Graaff, Sirpa Jylhä, Ruud Heshof, Ann Louise Worsøe Jørgensen, Thomas Haarmann
Publikováno v:
Applied Microbiology and Biotechnology 98 (2014) 3
Heshof, R, Jylhä, S, Haarmann, T, Jørgensen, A L W, Dalsgaard, T K & H. de Graaff, L 2014, ' A novel class of fungal lipoxygenases ', Applied Microbiology and Biotechnology, vol. 98, no. 3, pp. 1261-1270 . https://doi.org/10.1007/s00253-013-5392-x
Applied Microbiology and Biotechnology, 98(3), 1261-1270
Heshof, R, Jylhä, S, Haarmann, T, Jørgensen, A L W, Dalsgaard, T K & de Graaff, L H 2014, ' A novel class of fungal lipoxygenases ', Applied Microbiology and Biotechnology, vol. 98, no. 3, pp. 1261-1270 . https://doi.org/10.1007/s00253-013-5392-x
Heshof, R, Jylhä, S, Haarmann, T, Jørgensen, A L W, Dalsgaard, T K & H. de Graaff, L 2014, ' A novel class of fungal lipoxygenases ', Applied Microbiology and Biotechnology, vol. 98, no. 3, pp. 1261-1270 . https://doi.org/10.1007/s00253-013-5392-x
Applied Microbiology and Biotechnology, 98(3), 1261-1270
Heshof, R, Jylhä, S, Haarmann, T, Jørgensen, A L W, Dalsgaard, T K & de Graaff, L H 2014, ' A novel class of fungal lipoxygenases ', Applied Microbiology and Biotechnology, vol. 98, no. 3, pp. 1261-1270 . https://doi.org/10.1007/s00253-013-5392-x
Lipoxygenases (LOXs) are well-studied enzymes in plants and mammals. However, fungal LOXs are less studied. In this study, we have compared fungal LOX protein sequences to all known characterized LOXs. For this, a script was written using Shell comma
Autor:
Marja-Leena Laukkanen, Johanna Kallio, Nina Hakulinen, Janne Jänis, Kristiina Takkinen, Juha Rouvinen, Merja Niemi, Sirpa Jylhä
Publikováno v:
Niemi, M, Jänis, J, Jylhä, S, Kallio, J M, Hakulinen, N, Laukkanen, M-L, Takkinen, K & Rouvinen, J 2008, ' Characterization and crystallization of a recombinant IgE Fab fragment in complex with the bovine [beta]-lactoglobulin allergen ', Acta Crystallographica Section F: Structural Biology and Crystallization Communications, vol. 64, no. 1, pp. 25-28 . https://doi.org/10.1107/S174430910706160X
A D1 Fab fragment containing the allergen-binding variable domains of the IgE antibody was characterized by ESI FT-ICR mass spectrometry and crystallized with bovine beta-lactoglobulin (BLG) using the hanging-drop vapour-diffusion method at 293 K. X-
Autor:
Nina Hakulinen, Kristiina Takkinen, Hans Söderlund, Johanna Kallio, Soili Mäkinen-Kiljunen, Marja-Leena Laukkanen, Sirpa Jylhä, Merja Niemi, Juha Rouvinen, Tari Haahtela
Publikováno v:
Niemi, M, Jylhä, S, Laukkanen, M-L, Söderlund, H, Mäkinen-Kiljunen, S, Kallio, J M, Hakulinen, N, Haahtela, T, Takkinen, K & Rouvinen, J 2007, ' Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen ', Structure, vol. 15, no. 11, pp. 1413-1421 . https://doi.org/10.1016/j.str.2007.09.012
Allergies are caused by the immune reaction to commonly harmless proteins, allergens. This reaction is typified by immunoglobulin E (IgE) antibodies. We report the crystal structure of an IgE Fab fragment in complex with β-lactoglobulin (BLG), one o
Autor:
Jasmin Eidner, Leo H. de Graaff, Sirpa Jylhä, Antti Nyyssölä, Sónia A.O. Santos, Kim Langfelder, Kristiina Kruus, Armando J. D. Silvestre, Maria Rosário Domingues, Mário M.Q. Simões, Juan José Villaverde, Johanna Buchert, Tarja Tamminen, Vincent van der Vlist, Carlos Pascoal Neto, Minni Pirttimaa, Thomas Haarmann
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Villaverde, J J, van der Vlist, V, Santos, S A O, Haarmann, T, Langfelder, K, Pirttimaa, M, Nyyssölä, A, Jylhä, S, Tamminen, T, Kruus, K, de Graaff, L, Neto, C P, Simões, M M Q, Domingues, M R M, Silvestre, A J D, Eidner, J & Buchert, J 2013, ' Hydroperoxide production from linoleic acid by heterologous Gaeumannomyces graminis tritici lipoxygenase : Optimization and scale-up ', Chemical Engineering Journal, vol. 217, pp. 82-90 . https://doi.org/10.1016/j.cej.2012.11.090
Chemical Engineering Journal 217 (2013)
Chemical Engineering Journal, 217, 82-90
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Villaverde, J J, van der Vlist, V, Santos, S A O, Haarmann, T, Langfelder, K, Pirttimaa, M, Nyyssölä, A, Jylhä, S, Tamminen, T, Kruus, K, de Graaff, L, Neto, C P, Simões, M M Q, Domingues, M R M, Silvestre, A J D, Eidner, J & Buchert, J 2013, ' Hydroperoxide production from linoleic acid by heterologous Gaeumannomyces graminis tritici lipoxygenase : Optimization and scale-up ', Chemical Engineering Journal, vol. 217, pp. 82-90 . https://doi.org/10.1016/j.cej.2012.11.090
Chemical Engineering Journal 217 (2013)
Chemical Engineering Journal, 217, 82-90
Linoleic acid was converted into hydroperoxides by a Gaeumannomyces graminis tritici lipoxygenase produced recombinantly in Trichoderma reesei. Hydroperoxide production was optimized using a face-centred experimental design in order to study the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256485d21af5ba5a94c2f07f53aa8d61
Autor:
Janne Jänis, Tero Päivinen, Tari Haahtela, Sirpa Jylhä, Juha Rouvinen, Marja-Leena Laukkanen, Kristiina Takkinen, Hans Söderlund, Soili Mäkinen-Kiljunen, Merja Niemi
Publikováno v:
Rouvinen, J, Jänis, J, Laukkanen, M-L, Jylhä, S, Niemi, M, Päivinen, T, Mäkinen-Kiljunen, S, Haahtela, T, Söderlund, H & Takkinen, K 2010, ' Transient dimers of allergens ', PLoS ONE, vol. 5, no. 2, e9037 . https://doi.org/10.1371/journal.pone.0009037
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9037 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9037 (2010)
BackgroundAllergen-mediated cross-linking of IgE antibodies bound to the FcεRI receptors on the mast cell surface is the key feature of the type I allergy. If an allergen is a homodimer, its allergenicity is enhanced because it would only need one t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b8d20822604a866e50a60d97620d1d
https://cris.vtt.fi/en/publications/ba87dfd2-e887-4b57-9175-5e30be4db2f7
https://cris.vtt.fi/en/publications/ba87dfd2-e887-4b57-9175-5e30be4db2f7
Autor:
Tari Haahtela, Kristiina Takkinen, Hans Söderlund, Soili Mäkinen-Kiljunen, Sirpa Jylhä, Marja-Leena Laukkanen
Publikováno v:
Jylhä, S, Mäkinen-Kiljunen, S, Haahtela, T, Söderlund, H, Takkinen, K & Laukkanen, M-L 2009, ' Selection of recombinant IgE antibodies binding the ß-lactoglobulin allergen in a conformation-dependent manner ', Journal of Immunological Methods, vol. 350, no. 1-2, pp. 63-70 . https://doi.org/10.1016/j.jim.2009.07.007
Cow's milk allergy (CMA) is a common food allergy, especially among infants and young children. Approximately 85% of milk-allergic children outgrow their allergy by the age of three but the remaining 15% remain allergic. Bovine beta-lactoglobulin (BL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a817ec03ca67a98694957ae7ff9b7485
https://cris.vtt.fi/en/publications/13407c6b-1736-4809-a3b9-82ca29400709
https://cris.vtt.fi/en/publications/13407c6b-1736-4809-a3b9-82ca29400709