Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sirpa J Hirvonen-Santti"'
Autor:
Jorma J. Palvimo, Mikko Anttonen, JoAnne S. Richards, Olli A. Jänne, Markku Heikinheimo, Saija Savolainen, Venkataraman Sriraman, Sirpa J Hirvonen-Santti
Publikováno v:
Endocrinology. 145:2433-2444
Small nuclear RING finger protein (SNURF/RNF4) is a steroid receptor coregulator that is down-regulated in testicular germ cell cancer. In this work, we examined SNURF expression during murine fetal gonad development and postnatal ovarian folliculoge
Autor:
Saija Savolainen, Antti Rannikko, Jorma J. Palvimo, Olli A. Jänne, Marcus Nyberg, Sirpa J Hirvonen-Santti, Henrikki Santti
Publikováno v:
European Urology. 44:742-747
Objective: The role of estrogens and androgens in the etiology and progression of testicular germ cell cancer is poorly understood. To gain insight into the role of sex steroid action in testicular tumorigenesis, we have measured mRNAs encoding estro
Autor:
Jorma J. Palvimo, Jorma Toppari, Laura Mikkonen, Henrikki Santti, Sirpa J Hirvonen-Santti, Olli A. Jänne
Publikováno v:
Biochemical and Biophysical Research Communications. 308:139-147
PIASx gene encodes two SUMO E3 ligases that are highly expressed in the testis. We have isolated and analyzed the promoter of the murine PIASx gene. Electrophoretic mobility shift assays with testicular nuclear extracts showed that the proximal promo
Publikováno v:
Mechanisms of Development. 118(1-2):247-253
A small nuclear RING finger protein, termed SNURF (or RNF4), is a coregulator of androgen receptor-dependent transcription. To elucidate the physiological role of SNURF in vivo, cell type-specific localization and changes in SNURF mRNA and protein ac
Autor:
G Corte, M Panhuysen, Henrikki Santti, W Wurst, F Vauti, Olli A. Jänne, Laura Mikkonen, Ashish Anand, M Perera, Sirpa J Hirvonen-Santti, Jorma J. Palvimo, Jorma Toppari
Publikováno v:
Journal of molecular endocrinology. 34(3)
PIASx belongs to the PIAS protein family, the members of which modulate activities of several transcription factors and act as E3 ligases in the sumoylation pathway. The PIASx gene is highly expressed in testis, suggesting a role in spermatogenesis.