Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds.

Autor: Kwong HS; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Paloni M; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Grandvuillemin L; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Sirounian S; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Ancelin A; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Lai-Kee-Him J; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Grimaldi M; IRCM (Institut de Recherche en Cancérologie de Montpellier), Univ Montpellier, Inserm, ICM, Montpellier, France., Carivenc C; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Lancey C; Leicester Institute of Structural & Chemical Biology and Department of Molecular & Cell Biology, University of Leicester, Lancaster Rd, Leicester LE1 7HB, UK., Ragan TJ; Leicester Institute of Structural & Chemical Biology and Department of Molecular & Cell Biology, University of Leicester, Lancaster Rd, Leicester LE1 7HB, UK., Hesketh EL; Leicester Institute of Structural & Chemical Biology and Department of Molecular & Cell Biology, University of Leicester, Lancaster Rd, Leicester LE1 7HB, UK., Balaguer P; IRCM (Institut de Recherche en Cancérologie de Montpellier), Univ Montpellier, Inserm, ICM, Montpellier, France., Barducci A; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France., Gruszczyk J; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France. Electronic address: jakub.gruszczyk@cbs.cnrs.fr., Bourguet W; CBS (Centre de Biologie Structurale), Univ Montpellier, CNRS, Inserm, Montpellier, France. Electronic address: william.bourguet@cbs.cnrs.fr.

Publikováno v: Journal of molecular biology [J Mol Biol] 2024 Feb 01; Vol. 436 (3), pp. 168411. Date of Electronic Publication: 2023 Dec 20.