Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sirolimus/analogs & derivatives"'
Autor:
Michael Platten, G. Pesce, Thierry Gorlia, Kirsten Hopkins, Vassilis Golfinopoulos, Markus Kosch, Wolfgang Wick, Jean-Sebastien Frenel, Christine Marosi, Jonathan Steuve, Michael Weller, Mario Campone, Martin J. van den Bent, Antje Wick, Benoit Lhermitte, Salvador Villà, Krisztian Homicsko, Astrid Weyerbrock, Monika E. Hegi, Pierre Bady, Marie-France Hamou, Damien Ricard, Patrick Roth, Alba A. Brandes, Martin J.B. Taphoorn, Roger Stupp
Publikováno v:
Clinical Cancer Research, 22(19), 4797-4806. American Association for Cancer Research Inc.
Clinical Cancer Research, 22(19), 4797-4806
Clinical Cancer Research
Clinical cancer research, vol. 22, no. 19, pp. 4797-4806
Clinical Cancer Research, 22(19), 4797-4806
Clinical Cancer Research
Clinical cancer research, vol. 22, no. 19, pp. 4797-4806
Purpose: EORTC 26082 assessed the activity of temsirolimus in patients with newly diagnosed glioblastoma harboring an unmethylated O6 methylguanine-DNA-methyltransferase (MGMT) promoter. Experimental Design: Patients (n = 257) fulfilling eligibility
Autor:
Lars Jakobsen, Evald Høj Christiansen, Jakob Hjort, Lars Romer Krusell, Christian Juhl Terkelsen, Lisette Okkels Jensen, Anne Kaltoft, Steen Dalby Kristensen, Jens Flensted Lassen, Karsten Tange Veien, Niels Ramsing Holm, Jouke Dijkstra, Morten Madsen, Hans Erik Bøtker, Michael Maeng, Ida R. Balleby, Lene Nyhus Andreasen, Knud Nørregaard Hansen
Publikováno v:
Andreasen, L N, Holm, N R, Balleby, I R, Krusell, L R, Mæng, M, Jakobsen, L, Veien, K T, Hansen, K N, Kristensen, S D, Hjort, J, Kaltoft, A, Dijkstra, J, Terkelsen, C J, Lassen, J F, Madsen, M, Bøtker, H E, Jensen, L O & Christiansen, E H 2018, ' Randomized comparison of sirolimus eluting, and biolimus eluting bioresorbable polymer stents : the SORT-OUT VII optical coherence tomography study ', European Heart Journal Cardiovascular Imaging, vol. 19, no. 3, pp. 329–338 . https://doi.org/10.1093/ehjci/jex035
Andreasen, L N, Holm, N R, Balleby, I R, Krusell, L R, Maeng, M, Jakobsen, L, Veien, K T, Hansen, K N, Kristensen, S D, Hjort, J, Kaltoft, A, Dijkstra, J, Terkelsen, C J, Lassen, J F, Madsen, M, Bøtker, H E, Jensen, L O & Christiansen, E H 2018, ' Randomized comparison of sirolimus eluting, and biolimus eluting bioresorbable polymer stents : the SORT-OUT VII optical coherence tomography study ', European Heart Journal Cardiovascular Imaging, vol. 19, no. 3, pp. 329-338 . https://doi.org/10.1093/ehjci/jex035
Andreasen, L N, Holm, N R, Balleby, I R, Krusell, L R, Maeng, M, Jakobsen, L, Veien, K T, Hansen, K N, Kristensen, S D, Hjort, J, Kaltoft, A, Dijkstra, J, Terkelsen, C J, Lassen, J F, Madsen, M, Bøtker, H E, Jensen, L O & Christiansen, E H 2018, ' Randomized comparison of sirolimus eluting, and biolimus eluting bioresorbable polymer stents : the SORT-OUT VII optical coherence tomography study ', European Heart Journal Cardiovascular Imaging, vol. 19, no. 3, pp. 329-338 . https://doi.org/10.1093/ehjci/jex035
Aims: To show non-inferiority of the 67- or 87 µm thick, sirolimus-eluting Orsiro drug eluting stent (DES) to the 122 µm thick, biolimus-eluting Nobori DES regarding size of vessel lumen outside the stent at 13-month follow-up.Methods and results:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa6b1aa27b8460d13c50a2d628bc013
https://portal.findresearcher.sdu.dk/da/publications/e74fb794-744e-4482-8a15-f399e18dea87
https://portal.findresearcher.sdu.dk/da/publications/e74fb794-744e-4482-8a15-f399e18dea87
Publikováno v:
Clinical Science, Vol. 129, No 10 (2015) pp. 895-914
Clinical science (London England : 1979)
Clinical science (London England : 1979)
mTOR (mechanistic target of rapamycin) functions as the central regulator for cell proliferation, growth and survival. Up-regulation of proteins regulating mTOR, as well as its downstream targets, has been reported in various cancers. This has promot
Autor:
Hervé Sartelet, Anne-Laure Rougemont, Raouf Fetni, Monique Fabre, Stefan Michiels, Gilles Vassal, Mona Beaunoyer, Michel Duval, M. Castaing
Publikováno v:
Human Pathology, Vol. 42, No 11 (2011) pp. 1727-39
Neuroblastoma is a malignant pediatric tumor with poor survival. The phosphatidylinositol 3'-kinase/AKT pathway is a crucial regulator of cellular processes including apoptosis. Thioredoxin 1, an inhibitor of tumor-suppressor phosphatase and tensin h
Publikováno v:
Expert Review of Gastroenterology & Hepatology. 5:563-566
Expert Rev Gastroenterol Hepatol
Autor:
D. Solbu, Claus Bistrup, Helene Andersson, Bengt Gustafsson, Jesper Melchior Hansen, Bengt von zur Mühlen, Lars Mjörnstedt, Bente Jespersen, Søren Schwartz Sørensen, Hallvard Holdaas
Publikováno v:
Mjörnstedt, L, Schwartz Sørensen, S, von Zur Mühlen, B, Jespersen, B, Hansen, J M, Bistrup, C, Andersson, H, Gustafsson, B, Solbu, D & Holdaas, H 2015, ' Renal function three years after early conversion from a calcineurin inhibitor to everolimus : results from a randomized trial in kidney transplantation ', Transplant International, vol. 28, no. 1, pp. 42-51 . https://doi.org/10.1111/tri.12437
Mjörnstedt, L, Schwartz Sørensen, S, von Zur Mühlen, B, Jespersen, B, Hansen, J M, Bistrup, C, Andersson, H, Gustafsson, B, Solbu, D & Holdaas, H 2015, ' Renal function three years after early conversion from a calcineurin inhibitor to everolimus : results from a randomized trial in kidney transplantation ', Transplant international : official journal of the European Society for Organ Transplantation, vol. 28, no. 1, pp. 42-51 . https://doi.org/10.1111/tri.12437
Mjörnstedt, L, Schwartz Sørensen, S, von Zur Mühlen, B, Jespersen, B, Hansen, J M, Bistrup, C, Andersson, H, Gustafsson, B, Solbu, D & Holdaas, H 2015, ' Renal function three years after early conversion from a calcineurin inhibitor to everolimus : results from a randomized trial in kidney transplantation ', Transplant international : official journal of the European Society for Organ Transplantation, vol. 28, no. 1, pp. 42-51 . https://doi.org/10.1111/tri.12437
Summary In a 36-month, open-label, multicenter trial, 202 kidney transplant recipients were randomized at week 7 post-transplant to convert to everolimus or remain on cyclosporine: 182 were analyzed to month 36 (92 everolimus, 90 controls). Mean (SD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8013f8d6ab68fef9f774244b1d482f32
https://pure.au.dk/portal/da/publications/renal-function-three-years-after-early-conversion-from-a-calcineurin-inhibitor-to-everolimus(73c44c36-9b03-44c7-a2b7-17fbda919257).html
https://pure.au.dk/portal/da/publications/renal-function-three-years-after-early-conversion-from-a-calcineurin-inhibitor-to-everolimus(73c44c36-9b03-44c7-a2b7-17fbda919257).html
Autor:
de Souza, Cristiano Freitas, Mouallem, Anwar Mohamed El, de Brito, Fábio Sândoli, Abizaid, Alexandre Antônio Cunha, Almeida, Breno Oliveira, Almeida, Amanda Gonçalves, Nascimento, Teresa Cristina Dias Cunha, Perin, Marco Antonio, Caixeta, Adriano
Publikováno v:
Einstein (São Paulo), Volume: 11, Issue: 3, Pages: 350-356, Published: SEP 2013
Einstein
Einstein
OBJETIVO: Avaliar a incidência de eventos adversos cardíacos maiores (morte cardíaca, infarto agudo do miocárdio ou necessidade de nova revascularização do vaso-alvo) em 1 ano em pacientes do "mundo real". MÉTODOS: O registro EINSTEIN é um es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e68b5ab7929159e57ef76ff773f1a56
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082013000300015&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082013000300015&lng=en&tlng=en
Autor:
Vallin, Mélanie, Guillaud, Olivier, Morard, Isabelle, Gagnieu, Marie-Claude, Mentha, Gilles, Adham, Mustapha, Morelon, Emmanuel, Boillot, Olivier, Giostra, Emiliano, Dumortier, Jérôme
Publikováno v:
Clinical Transplantation, Vol. 25, No 4 (2011) pp. 660-9
The aim of this study was to evaluate the tolerability of the conversion from calcineurin inhibitor (CNI) to everolimus (ERL) in maintenance liver transplant (LT) recipients.From January 2005 to March 2008, ERL was introduced after LT as maintenance
Autor:
Saraya Tavornpanich, Weerapong Thanapongtharm, Xiangming Xiao, Patrick Gasqui, François Roger, David Abrial, Myriam Charras-Garrido, Christian Ducrot, Mathilde Paul, Marius Gilbert
Publikováno v:
Veterinary Research
Veterinary Research, BioMed Central, 2010, 41 (3), pp.28-42. ⟨10.1051/vetres/2009076⟩
Veterinary Research 3 (41), 28-42. (2010)
Veterinary research, 41 (3
Veterinary Research, BioMed Central, 2010, 41 (3), pp.28-42. ⟨10.1051/vetres/2009076⟩
Veterinary Research 3 (41), 28-42. (2010)
Veterinary research, 41 (3
Beginning in 2003, highly pathogenic avian influenza (HPAI) H5N1 virus spread across Southeast Asia, causing unprecedented epidemics. Thailand was massively infected in 2004 and 2005 and continues today to experience sporadic outbreaks. While researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f571583cce3a4d4b600ad2a26a1b4c2c
https://hal.archives-ouvertes.fr/hal-00903153
https://hal.archives-ouvertes.fr/hal-00903153