Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Siro Luvisetto"'
Autor:
Siro Luvisetto
Publikováno v:
Toxins, Vol 15, Iss 9, p 540 (2023)
Studies on animals and humans have amply demonstrated the therapeutic efficacy of botulinum neurotoxins (BoNTs) in many pathologies [...]
Externí odkaz:
https://doaj.org/article/e709e5fd8f4b4cd19832839acd72ccb7
Autor:
Valentina Mastrorilli, Federica De Angelis, Valentina Vacca, Flaminia Pavone, Siro Luvisetto, Sara Marinelli
Publikováno v:
Toxins, Vol 15, Iss 4, p 248 (2023)
Xeomin® is a commercial formulation of botulinum neurotoxin type A (BoNT/A) clinically authorized for treating neurological disorders, such as blepharospasm, cervical dystonia, limb spasticity, and sialorrhea. We have previously demonstrated that sp
Externí odkaz:
https://doaj.org/article/16fedbcc37d7426fa7f2dc724b21dd09
Autor:
Siro Luvisetto
Publikováno v:
Toxins, Vol 14, Iss 10, p 704 (2022)
In recent years, numerous studies have highlighted the significant use of botulinum neurotoxins (BoNTs) in the human therapy of various motor and autonomic disorders. The therapeutic action is exerted with the selective cleavage of specific sites of
Externí odkaz:
https://doaj.org/article/094df9a8bb254a95a8f0b51796210d00
Autor:
Silvia Giannattasio, Giacomo Giacovazzo, Agnese Bonato, Carla Caruso, Siro Luvisetto, Roberto Coccurello, Maurizia Caruso
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract The mitogen-induced D-type cyclins (D1, D2 and D3) are regulatory subunits of the cyclin-dependent kinases CDK4 and CDK6 that drive progression through the G1 phase of the cell cycle. In skeletal muscle, cyclin D3 plays a unique function in
Externí odkaz:
https://doaj.org/article/adf1b3c9b11f492ea0cdab5e5ffaa16c
Autor:
Siro Luvisetto
Publikováno v:
Toxins, Vol 13, Iss 11, p 751 (2021)
Botulinum neurotoxins (BoNTs) are potent inhibitors of synaptic vesicle fusion and transmitter release. The natural target of BoNTs is the peripheral neuromuscular junction (NMJ) where, by blocking the release of acetylcholine (ACh), they functionall
Externí odkaz:
https://doaj.org/article/8e25d6a9b4a4465681a4f0f2dcf7035f
Autor:
Magdalena Zychowska, Ewelina Rojewska, Wioletta Makuch, Siro Luvisetto, Flaminia Pavone, Sara Marinelli, Barbara Przewlocka, Joanna Mika
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 1020-1023 (2016)
Our data show that botulinum toxin A (BoNT/A) didn’t influence motor functions in naïve and CCI-exposed rats, but diminished the neuropathic pain-related behavior. The results indicate that BoNT/A administration diminished the spinal Iba-1 positiv
Externí odkaz:
https://doaj.org/article/7cb0118904ae4a28946c1cb2b7938467
Autor:
Siro Luvisetto
Publikováno v:
Toxins, Vol 12, Iss 9, p 601 (2020)
Botulinum toxins (BoNTs) are a true wonder of nature [...]
Externí odkaz:
https://doaj.org/article/d735375979eb490e8c1a3a41c7b8f94c
Autor:
Valentina Vacca, Luca Madaro, Federica De Angelis, Daisy Proietti, Stefano Cobianchi, Tiziana Orsini, Pier Lorenzo Puri, Siro Luvisetto, Flaminia Pavone, Sara Marinelli
Publikováno v:
Toxins, Vol 12, Iss 8, p 491 (2020)
Botulinum neurotoxin type A (BoNT/A) is a major therapeutic agent that has been proven to be a successful treatment for different neurological disorders, with emerging novel therapeutic indications each year. BoNT/A exerts its action by blocking SNAR
Externí odkaz:
https://doaj.org/article/b92d9bc176224897a44588be30e3854d
Autor:
Siro Luvisetto
Publikováno v:
Toxins, Vol 12, Iss 7, p 434 (2020)
Botulinum neurotoxins (BoNTs) are toxins produced by the bacteria Clostridium botulinum, the causing agent for botulism, in different serotypes, seven of which (A–G) are well characterized, while others, such as H or FA, are still debated. BoNTs ex
Externí odkaz:
https://doaj.org/article/d971f4072b404afd88f1e4be6f216808
Publikováno v:
Toxins, Vol 7, Iss 9, Pp 3818-3844 (2015)
Botulinum neurotoxin A (BoNT/A) is a toxin produced by the naturally-occurring Clostridium botulinum that causes botulism. The potential of BoNT/A as a useful medical intervention was discovered by scientists developing a vaccine to protect against b
Externí odkaz:
https://doaj.org/article/431aa57dc9114b9e9ecee6d88444064e