Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sirisha Kudumala"'
Autor:
Hrvoje Augustin, Kieran McGourty, Marcus J Allen, Sirisha Kudumala Madem, Jennifer Adcott, Fiona Kerr, Chi Tung Wong, Alec Vincent, Tanja Godenschwege, Emmanuel Boucrot, Linda Partridge
Publikováno v:
PLoS Biology, Vol 15, Iss 9, p e2001655 (2017)
Lowered insulin/insulin-like growth factor (IGF) signaling (IIS) can extend healthy lifespan in worms, flies, and mice, but it can also have adverse effects (the "insulin paradox"). Chronic, moderately lowered IIS rescues age-related decline in neuro
Externí odkaz:
https://doaj.org/article/86acefcd2570465f95e24b7ce6e9926a
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76974 (2013)
A large number of different pathological L1CAM mutations have been identified that result in a broad spectrum of neurological and non-neurological phenotypes. While many of these mutations have been characterized for their effects on homophilic and h
Externí odkaz:
https://doaj.org/article/385c97b5f7bc4cd088311f63203419ce
Autor:
Noemí Cabré, Phillipp Hartmann, Cristina Llorente, Tetsuya Kouno, Yanhan Wang, Suling Zeng, Hyun Young Kim, Xinlian Zhang, Tatiana Kisseleva, Subramanian Iyer, Sirisha Kudumala, Bernd Schnabl
Publikováno v:
Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99e7e2e1d93e62ddbbd1306dd0610d46
https://doi.org/10.1097/hep.0000000000000324
https://doi.org/10.1097/hep.0000000000000324
Publikováno v:
Brain, Behavior and Evolution. 95:247-255
Amphetamine is a potent psychostimulant also used to treat attention deficit/hyperactivity disorder and narcolepsy. In vivo and in vitro data have demonstrated that amphetamine increases the amount of extra synaptic dopamine by both inhibiting reupta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d67806aa3c8350546e316a17cee3c6
https://doi.org/10.1159/000514858
https://doi.org/10.1159/000514858
Publikováno v:
Neurochemical Research
Amphetamine (AMPH) is a systemic stimulant used to treat a variety of diseases including Attention Deficit Hyperactive Disorder, narcolepsy and obesity. Previous data showed that by binding to catecholamine transporters, AMPH prevents the reuptake of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34889dc6c3a2186a452c376cebd4405
https://doi.org/10.1007/s11064-019-02938-7
https://doi.org/10.1007/s11064-019-02938-7
Publikováno v:
microPublication Biology
In vertebrates, the Attractin (Atrn) transmembrane protein family is comprised of ATRN, Attractin-like 1 (ATRNL1) and Multiple epidermal growth factor-like domain 8 (MEGF8) proteins, which contain an extensive extracellular domain with numerous prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd7583b06226e923d434f52ee528441
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The role of the Amyloid Precursor Protein (APP) in the pathology of Alzheimer's disease (AD) has been well studied. However, the normal function of APP in the nervous system is poorly understood. Here, we characterized the role of the Drosophila homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09b233af83eaa40cca9ccd674380e53
https://www.frontiersin.org/article/10.3389/fncel.2019.00322/full
https://www.frontiersin.org/article/10.3389/fncel.2019.00322/full
Publikováno v:
Journal of Visualized Experiments.
The swimming assay described in this protocol is a valid tool to identify proteins regulating the dopaminergic synapses. Similar to mammals, dopamine (DA) controls several functions in C. elegans including learning and motor activity. Conditions that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355593e48840a0fde5b39df872d3b708
https://doi.org/10.3791/59243-v
https://doi.org/10.3791/59243-v
Akademický článek
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Autor:
Chi Tung Wong, Alec J. Vincent, Linda Partridge, Jennifer Adcott, Marcus J. Allen, Emmanuel Boucrot, Hrvoje Augustin, Fiona Kerr, Sirisha Kudumala Madem, Kieran McGourty, Tanja A. Godenschwege
Publikováno v:
PLoS Biol
PLoS Biology
PLoS Biology, Vol 15, Iss 9, p e2001655 (2017)
PLoS Biology
PLoS Biology, Vol 15, Iss 9, p e2001655 (2017)
Lowered insulin/insulin-like growth factor (IGF) signaling (IIS) can extend healthy lifespan in worms, flies, and mice, but it can also have adverse effects (the “insulin paradox”). Chronic, moderately lowered IIS rescues age-related decline in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699841e3c97f66d23131a03962bfb994
https://doi.org/10.1371/journal.pbio.2001655
https://doi.org/10.1371/journal.pbio.2001655