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Akademický článek

Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors

Autor: Zeynep Soyer, Sirin Uysal, Sulunay Parlar, Ayse Hande Tarikogullari Dogan, Vildan Alptuzun

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 13-19 (2017)

A series of 4-phthalimidobenzenesulfonamide derivatives were designed, synthesized and evaluated for the inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Structures of the title compounds were confirmed by

Externí odkaz: https://doaj.org/article/4ea03bcd7b954ee28da24436fb4f7c31

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Design, synthesis, and biological evaluation of some novel naphthoquinone‐glycine / β‐alanine anilide derivatives as noncovalent proteasome inhibitors

Autor: Irem Tatar, Sirin Uysal, Sinem Yilmaz, Ayse H. Tarikogullari, Petek Ballar Kirmizibayrak, Zeynep Soyer

Publikováno v: Chemical Biology & Drug Design. 101:1283-1298

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44fc5c7c48f2e7c58e69990cb71ece5c
https://doi.org/10.1111/cbdd.14212

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Synthesis and Enzymological Characterization of Some 2-(Substituted-phenylamino) quinazolin-4(3H)-one Derivatives as Potent alpha-Glucosidase Inhibitors In Vitro

Autor: Zeynep Soyer, Emre Kadir Ayan, Sirin Uysal

Background: alpha-Glucosidase is an important hydrolytic enzyme playing a vital role in digestion of carbohydrates. It catalyzes the final step of carbohydrates digestion in biological systems and converts unabsorbed oligosaccharides and disaccharide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba4475bce277da69ae02330e2fbaf38
https://hdl.handle.net/11454/78169

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Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors

Autor: Petek Ballar Kirmizibayrak, Sirin Uysal, Merve Saylam, Zeynep Soyer, Sinem Yilmaz, Ayse Hande Tarikogullari

A series of novel 4-aminobenzensulfonamide/carboxamide derivatives bearing naphthoquinone pharmacophore were designed, sythesized and evaluated for their proteasome inhibitory and anti-proliferative activities against human breast cancer cell line (M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ceea7676ef3cc921102a373ac35001
https://hdl.handle.net/11454/61492

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Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors

Autor: Sülünay Parlar, Zeynep Soyer, Ayse Hande Tarikogullari Dogan, Vildan Alptüzün, Sirin Uysal

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 13-19 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry

WOS: 000392591100005
PubMed ID: 27766908
A series of 4-phthalimidobenzenesulfonamide derivatives were designed, synthesized and evaluated for the inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd7c57c39c340bc6abaf17fa17ec34b
https://doaj.org/article/4ea03bcd7b954ee28da24436fb4f7c31

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