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Akademický článek

Meldonium-induced steatosis is associated with increased delta 6 desaturation and reduced elongation of n-6 polyunsaturated fatty acids

Autor: Bodil Bjørndal, Siri Lunde Tungland, Pavol Bohov, Magne O. Sydnes, Simon N. Dankel, Lise Madsen, Rolf K Berge

Publikováno v: Liver Research, Vol 8, Iss 3, Pp 152-164 (2024)

Background and objective: Metabolic associated fatty liver disease (MAFLD) is associated with abnormal lipid metabolism. Mitochondrial dysfunction is considered an important factor in the onset of MAFLD, whereas altered fatty acid composition has bee

Externí odkaz: https://doaj.org/article/f184559c38b14a08a85a87ff27b29649

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Akademický článek

Changes in Plasma Pyruvate and TCA Cycle Metabolites upon Increased Hepatic Fatty Acid Oxidation and Ketogenesis in Male Wistar Rats

Autor: Simon Nitter Dankel, Tine-Lise Kalleklev, Siri Lunde Tungland, Marit Hallvardsdotter Stafsnes, Per Bruheim, Thomas Aquinas Aloysius, Carine Lindquist, Jon Skorve, Ottar Kjell Nygård, Lise Madsen, Bodil Bjørndal, Magne Olav Sydnes, Rolf Kristian Berge

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 21, p 15536 (2023)

Altered hepatic mitochondrial fatty acid β-oxidation and associated tricarboxylic acid (TCA) cycle activity contributes to lifestyle-related diseases, and circulating biomarkers reflecting these changes could have disease prognostic value. This stud

Externí odkaz: https://doaj.org/article/7c72d227ffa949bea6d0f1f274227d34

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Akademický článek

Liquid biopsies and patient-reported outcome measures for integrative monitoring of patients with early-stage breast cancer: a study protocol for the longitudinal observational Prospective Breast Cancer Biobanking (PBCB) study

Publikováno v: BMJ Open, Vol 12, Iss 4 (2022)

Introduction Breast cancer is still the most common malignancy among women worldwide. The Prospective Breast Cancer Biobank (PBCB) collects blood and urine from patients with breast cancer every 6 or 12 months for 11 years from 2011 to 2030 at two un

Externí odkaz: https://doaj.org/article/aa5275a655f8481d8710bf87d934c304

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Akademický článek

Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study

Autor: Tone Hoel Lende, Marie Austdal, Tone Frost Bathen, Anne Elin Varhaugvik, Ivar Skaland, Einar Gudlaugsson, Nina G. Egeland, Siri Lunde, Lars A. Akslen, Kristin Jonsdottir, Emiel A. M. Janssen, Håvard Søiland, Jan P. A. Baak

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-23 (2019)

Abstract Background The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative per-oral carbohydrate loa

Externí odkaz: https://doaj.org/article/02feefb2269b4c83be34c623c2ba5775

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Akademický článek

How well do doctors understand a scientific article in English when it is not their first language? A randomised controlled trial

Autor: Eva Skovlund, Magne Nylenna, Pål Gulbrandsen, Erlend Hem, Martine Rostadmo, Siri Lunde Strømme, Are Brean, Ragnhild Orstavik

Publikováno v: BMJ Open, Vol 11, Iss 6 (2021)

Introduction English is the lingua franca of science. How well doctors understand English is therefore crucial for their understanding of scientific articles. However, only 5% of the world’s population have English as their first language.Methods O

Externí odkaz: https://doaj.org/article/825fcb91cd7f4e7ab827f3275da65781

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Akademický článek

The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients

Autor: Nina G. Egeland, Siri Lunde, Kristin Jonsdottir, Tone H. Lende, Deirdre Cronin-Fenton, Bjørnar Gilje, Emiel A. M. Janssen, Håvard Søiland

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 24243-24275 (2015)

Endocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. However, resistance to endocrine therapy leads to breast cancer relapse. The recent extension of adjuvant tamoxifen treatment up to 10 years actua

Externí odkaz: https://doaj.org/article/5392575f56c44e069c42c12d90aaff93

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