Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sireesha Yerrathota"'
Autor:
Charles Bengtson, Neerupma Silswal, Nathalie Baumlin, Makoto Yoshida, John Dennis, Sireesha Yerrathota, Michael Kim, Matthias Salathe
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10956 (2022)
Highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators have led to dramatic improvements in lung function in many people with cystic fibrosis (PwCF). However, the efficacy of CFTR modulators may be hindered by persiste
Externí odkaz:
https://doaj.org/article/1c314e1c326c40ef901664606885299c
Autor:
Praveen Chakravarthi Veeraragavulu, Nanda Kumar Yellapu, Sireesha Yerrathota, Pradeepkiran Jangampalli Adi, Bhaskar Matcha
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 2217-2224 (2019)
Externí odkaz:
https://doaj.org/article/1123e371b7594a72ae74e0979dc15d52
Publikováno v:
Data in Brief, Vol 35, Iss , Pp 106873- (2021)
The Notch signaling pathway is an important conserved pathway for normal homeostasis during development. However, targeted deletion of Notch4 (Notch4d1) or Notch3 (Notch3d1) in mice is not lethal. In fact, both Notch4d1 and Notch3d1 mice develop norm
Externí odkaz:
https://doaj.org/article/0475282d66d44af0864b1dfa75b7c5fd
Autor:
Priyanka S. Radadiya, Mackenzie M. Thornton, Rajni V. Puri, Sireesha Yerrathota, Johnny Dinh-Phan, Brenda Magenheimer, Dharmalingam Subramaniam, Pamela V. Tran, Hao Zhu, Subhashini Bolisetty, James P. Calvet, Darren P. Wallace, Madhulika Sharma
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Despite the recent launch of tolvaptan, the search for safer polycystic kidney disease (PKD) drugs continues. Ciclopirox (CPX) or its olamine salt (CPX-O) is contained in a number of commercially available antifungal agents. CPX is also reported to p
Externí odkaz:
https://doaj.org/article/6e7056f708454bdc9cd717dfd744b149
Autor:
V. Praveen Chakravarthi, Sireesha Yerrathota, Priyanka Radadiya, Clark Bloomer, Sumedha Gunewardhana, Madhulika Sharma
Publikováno v:
Data in Brief, Vol 30, Iss , Pp 105562- (2020)
Tg26 mice are robust models of human immunodeficiency virus 1 associated nephropathy (HIVAN). These mice are useful for HIVAN pathology analysis, and recent studies suggest that the Tg26 mouse model is an excellent model of other chronic kidney disea
Externí odkaz:
https://doaj.org/article/fde61db2aecf42378b0b23290eb5fc89
Autor:
Rajni Vaid Puri, Sireesha Yerrathota, Trisha Home, Jessica Y. Idowu, V. Praveen Chakravarthi, Christopher J. Ward, Pravin C. Singhal, Gregory B. Vanden Heuvel, Timothy A. Fields, Madhulika Sharma
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 12 (2019)
Notch pathway activation plays a central role in the pathogenesis of many glomerular diseases. We have previously shown that Notch4 expression was upregulated in various renal cells in human immunodeficiency virus (HIV)-associated nephropathy (HIVAN)
Externí odkaz:
https://doaj.org/article/a544e1427d1144e49e29e1d352cfedb9
Autor:
Sireesha Yerrathota, Nanda Kumar Yellapu, Pradeepkiran Jangampalli Adi, Bhaskar Matcha, Praveen Chakravarthi Veeraragavulu
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 2217-2224 (2019)
ACS Omega
ACS Omega
Insulin receptor substrate 1 (IRS1) is one of the major substrates for the IR, and their interaction mediates several downstream insulin signaling pathways. In this study, we have identified three novel mutations in the IRS1 gene of type 2 diabetic (
Autor:
Michael W. Wolfe, M.A. Karim Rumi, Katherine F. Roby, Vincentaben Khristi, Eddie Dai, Subhra Ghosh, V. Praveen Chakravarthi, Sireesha Yerrathota
Publikováno v:
Endocrinology. 159:3860-3873
Hypothalamic expression of Kiss1 plays an essential role in the onset of puberty, gonadal development, and ovulation. Estrogens regulate the expression of Kiss1 in the hypothalamus through estrogen receptor-α. Kiss1 is also expressed in the ovary, w
Autor:
Sumedha Gunewardhana, Priyanka S. Radadiya, Sireesha Yerrathota, V. Praveen Chakravarthi, Madhulika Sharma, Clark Bloomer
Publikováno v:
Data in Brief
Data in Brief, Vol 30, Iss, Pp 105562-(2020)
Data in Brief, Vol 30, Iss, Pp 105562-(2020)
Tg26 mice are robust models of human immunodeficiency virus 1 associated nephropathy (HIVAN). These mice are useful for HIVAN pathology analysis, and recent studies suggest that the Tg26 mouse model is an excellent model of other chronic kidney disea