Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sireesha Mamillapalli"'
Autor:
Fabiana Freire Mendes de Oliveira, Sireesha Mamillapalli, Srinivas Gonti, Robert N. Brey, Han Li, Jarad Schiffer, Arturo Casadevall, James G. Bann
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Protective antigen (PA) is a component of anthrax toxin that can elicit toxin-neutralizing antibody responses. PA is also the major antigen in the current vaccine to prevent anthrax, but stability problems with recombinant proteins have comp
Externí odkaz:
https://doaj.org/article/c5b08a3442284ba9b28cd6995fad9269
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd9320dee7766c95171bd447be3af16
https://doi.org/10.1096/fasebj.2022.36.s1.r5831
https://doi.org/10.1096/fasebj.2022.36.s1.r5831
Publikováno v:
Human Microbiome ISBN: 9789811676710
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac0ee73b403c09ae95314a567b574ad
https://doi.org/10.1007/978-981-16-7672-7_11
https://doi.org/10.1007/978-981-16-7672-7_11
Autor:
Harry Scott, Wei Huang, Kiran Andra, Sireesha Mamillapalli, Srinivas Gonti, Alexander Day, Kaiming Zhang, Nurjahan Mehzabeen, Kevin P. Battaile, Anjali Raju, Scott Lovell, James G. Bann, Derek J. Taylor
Publikováno v:
Journal of Molecular Biology. 434:167548
The tripartite protein complex produced by anthrax bacteria (Bacillus anthracis) is a member of the AB family of β-barrel pore-forming toxins. The protective antigen (PA) component forms an oligomeric prepore that assembles on the host cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94cf653e78428015b2cc7f14bbdbb75
https://doi.org/10.1016/j.jmb.2022.167548
https://doi.org/10.1016/j.jmb.2022.167548
Autor:
Sireesha Mamillapalli, James G. Bann, Jarad Schiffer, Srinivas Gonti, Han Li, Fabiana Freire Mendes de Oliveira, Arturo Casadevall, Robert N. Brey
Publikováno v:
mSphere
mSphere, Vol 5, Iss 1 (2020)
mSphere, Vol 5, Iss 1, p e00556-19 (2020)
mSphere, Vol 5, Iss 1 (2020)
mSphere, Vol 5, Iss 1, p e00556-19 (2020)
The anthrax toxin PA is the major immunogen in the current anthrax vaccine (anthrax vaccine adsorbed). Improving the anthrax vaccine for avoidance of a cold chain necessitates improvements in the thermodynamic stability of PA. We address how stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1597a9e8d31a756e575d439ad1646276
https://pubmed.ncbi.nlm.nih.gov/31941807
https://pubmed.ncbi.nlm.nih.gov/31941807
Publikováno v:
Protein Science. 26:355-364
The major immunogenic component of the current anthrax vaccine, anthrax vaccine adsorbed (AVA) is protective antigen (PA). We have shown recently that the thermodynamic stability of PA can be significantly improved by binding to the Von-Willebrand fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ebd7fd7fccf2065222fe3a93e67237f
https://doi.org/10.1002/pro.3087
https://doi.org/10.1002/pro.3087
Publikováno v:
Biochemistry
Protective antigen (PA) mediates entry of edema factor (EF) and lethal factor (LF) into the cytoplasmic space of the cells through the formation of a membrane-spanning pore. To do this, PA must initially bind to a host cellular receptor. Recent mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40694e931f676246c813c23ce3b299ca
https://doi.org/10.1021/bi500718g
https://doi.org/10.1021/bi500718g