Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Siranush Sarkizova"'
Autor:
Shira Weingarten-Gabbay, Da-Yuan Chen, Siranush Sarkizova, Hannah B. Taylor, Matteo Gentili, Gabrielle M. Hernandez, Leah R. Pearlman, Matthew R. Bauer, Charles M. Rice, Karl R. Clauser, Nir Hacohen, Steven A. Carr, Jennifer G. Abelin, Mohsan Saeed, Pardis C. Sabeti
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113596- (2024)
Summary: Targeted synthetic vaccines have the potential to transform our response to viral outbreaks, yet the design of these vaccines requires a comprehensive knowledge of viral immunogens. Here, we report severe acute respiratory syndrome coronavir
Externí odkaz:
https://doaj.org/article/db8ea015b89d430fb372f8118aea4ea2
Autor:
Patrick C. Lee, Susan Klaeger, Phuong M. Le, Keegan Korthauer, Jingwei Cheng, Varsha Ananthapadmanabhan, Thomas C. Frost, Jonathan D. Stevens, Alan Y.L. Wong, J. Bryan Iorgulescu, Anna Y. Tarren, Vipheaviny A. Chea, Isabel P. Carulli, Camilla K. Lemvigh, Christina B. Pedersen, Ashley K. Gartin, Siranush Sarkizova, Kyle T. Wright, Letitia W. Li, Jason Nomburg, Shuqiang Li, Teddy Huang, Xiaoxi Liu, Lucas Pomerance, Laura M. Doherty, Annie M. Apffel, Luke J. Wallace, Suzanna Rachimi, Kristen D. Felt, Jacquelyn O. Wolff, Elizabeth Witten, Wandi Zhang, Donna Neuberg, William J. Lane, Guanglan Zhang, Lars R. Olsen, Manisha Thakuria, Scott J. Rodig, Karl R. Clauser, Gabriel J. Starrett, John G. Doench, Sara J. Buhrlage, Steven A. Carr, James A. DeCaprio, Catherine J. Wu, Derin B. Keskin
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Cancers avoid immune surveillance through an array of mechanisms, including perturbation of HLA class I antigen presentation. Merkel cell carcinoma (MCC) is an aggressive, HLA-I–low, neuroendocrine carcinoma of the skin often caused by the Merkel c
Externí odkaz:
https://doaj.org/article/60397b52dbf342a38a8b4cfb3371eac6
Autor:
Wouter J. Venema, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander, Efstratios Stratikos, Siranush Sarkizova, Lars T. van der Veken, George M. C. Janssen, Peter A. van Veelen, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Birdshot Uveitis (BU) is a blinding inflammatory eye condition that only affects HLA-A29-positive individuals. Genetic association studies linked ERAP2 with BU, an aminopeptidase which trims peptides before their presentation by HLA class I at the ce
Externí odkaz:
https://doaj.org/article/96774bd91fe94255b5f0907aab6bb0ce
Autor:
Jonathan H. Chen, Linda T. Nieman, Maxwell Spurrell, Vjola Jorgji, Peter Richieri, Katherine H. Xu, Roopa Madhu, Milan Parikh, Izabella Zamora, Arnav Mehta, Christopher S. Nabel, Samuel S. Freeman, Joshua D. Pirl, Chenyue Lu, Catherine B. Meador, Jaimie L. Barth, Mustafa Sakhi, Alexander L. Tang, Siranush Sarkizova, Colles Price, Nicolas F. Fernandez, George Emanuel, Jiang He, Katrina Van Raay, Jason W. Reeves, Keren Yizhak, Matan Hofree, Angela Shih, Moshe Sade-Feldman, Genevieve M. Boland, Karin Pelka, Martin Aryee, Ilya Korsunsky, Mari Mino-Kenudson, Justin F. Gainor, Nir Hacohen
Publikováno v:
bioRxiv
The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor spatially-localized multicellular ‘immunity hubs’ defined by expression of the T cell-attracting chemokinesCXCL10/CXCL11and abundant T cells. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34a8311fe1a0ffaf6c8bf19497a54e4
https://europepmc.org/articles/PMC10104028/
https://europepmc.org/articles/PMC10104028/
Autor:
Vincenzo Bronte, Peter J. Murray, Silvio Bicciato, Emilio Bria, Luisa Carbognin, Aldo Scarpa, Rita Lawlor, Stefano Piccolo, Luca Azzolin, Nir Hacohen, David Lieb, Siranush Sarkizova, Thomas Eisenhaure, Giulia Borile, Federico Boschi, Massimo Rugge, Matteo Fassan, Manuela Iezzi, Alessia Lamolinara, Anna Simonelli, Stefania Canè, Stefano Ugel, Francesco De Sanctis, Vincenzo Ingangi, Francesca Hofer, Rosalinda Trovato, Ilaria Marigo
Tumor-associated macrophages (TAM) are regulators of extracellular matrix (ECM) remodeling and metastatic progression, the main cause of cancer-associated death. We found that disabled homolog 2 mitogen-responsive phosphoprotein (DAB2) is highly expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c952050333b46b1b7c684b390757b60e
https://doi.org/10.1158/2159-8290.c.6547787.v1
https://doi.org/10.1158/2159-8290.c.6547787.v1
Autor:
Vincenzo Bronte, Peter J. Murray, Silvio Bicciato, Emilio Bria, Luisa Carbognin, Aldo Scarpa, Rita Lawlor, Stefano Piccolo, Luca Azzolin, Nir Hacohen, David Lieb, Siranush Sarkizova, Thomas Eisenhaure, Giulia Borile, Federico Boschi, Massimo Rugge, Matteo Fassan, Manuela Iezzi, Alessia Lamolinara, Anna Simonelli, Stefania Canè, Stefano Ugel, Francesco De Sanctis, Vincenzo Ingangi, Francesca Hofer, Rosalinda Trovato, Ilaria Marigo
Supplementary Figures, Tables, Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a214a6f2439b7d663c90e03d1246aeb
https://doi.org/10.1158/2159-8290.22535201
https://doi.org/10.1158/2159-8290.22535201
Autor:
Vincenzo Bronte, Peter J. Murray, Silvio Bicciato, Emilio Bria, Luisa Carbognin, Aldo Scarpa, Rita Lawlor, Stefano Piccolo, Luca Azzolin, Nir Hacohen, David Lieb, Siranush Sarkizova, Thomas Eisenhaure, Giulia Borile, Federico Boschi, Massimo Rugge, Matteo Fassan, Manuela Iezzi, Alessia Lamolinara, Anna Simonelli, Stefania Canè, Stefano Ugel, Francesco De Sanctis, Vincenzo Ingangi, Francesca Hofer, Rosalinda Trovato, Ilaria Marigo
Marker genes for each cell type identified in tumor-infiltrating myeloid cells.Related to Fig.1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436a07667db2edfb83bc552bd33586f8
https://doi.org/10.1158/2159-8290.22535213
https://doi.org/10.1158/2159-8290.22535213
Autor:
Nicoletta Cieri, Nidhi Hookeri, Kari Stromhaug, Jonathan Stevens, Kameron Kooshesh, Susan Klaeger, Karl R. Clauser, Siranush Sarkizova, David A. Braun, Livius Penter, Giacomo Oliveira, Haesook T. Kim, William J. Lane, Shuqiang Li, Kenneth J. Livak, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Derin B. Keskin, Chip Stewart, Alexander Gusev, Gad Getz, Catherine J. Wu
Publikováno v:
Blood. 140:4762-4764
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09c6375f30f7349a9293a7d0d7fbb607
https://doi.org/10.1182/blood-2022-162841
https://doi.org/10.1182/blood-2022-162841
Autor:
Suzanna Rachimi, Susan Klaeger, Patrick C. Lee, Phuong M. Le, Vipheaviny A. Chea, Isabel P. Carulli, Varsha Ananthapadmanabhan, Anna Tarren, Siranush Sarkizova, Annie Apffel, Karl R. Clauser, James A. DeCaprio, Steven A. Carr, Catherine J. Wu, Derin B. Keskin
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e9e16bab20a2ba0ab28f68360d7a4b
https://doi.org/10.1096/fasebj.2022.36.s1.r3864
https://doi.org/10.1096/fasebj.2022.36.s1.r3864
Autor:
Aviv Regev, Orr Ashenberg, Marcin Tabaka, Yanay Rosen, Joshua Gould, Nir Hacohen, Bo Li, Yiming Yang, Siranush Sarkizova, Michal Slyper, Alexandra-Chloé Villani, Monika S. Kowalczyk, Orit Rozenblatt-Rosen, Timothy L. Tickle
Publikováno v:
Nature methods
Massively parallel single-cell and single-nucleus RNA sequencing has opened the way to systematic tissue atlases in health and disease, but as the scale of data generation is growing, so is the need for computational pipelines for scaled analysis. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc65716c2186256dbc2ea5947d33afaf
http://europepmc.org/articles/PMC7437817
http://europepmc.org/articles/PMC7437817