Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Siralee Munshi"'
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol 2011, Iss default, Pp 5-16 (2011)
Shitalkumar P Zambad1, Siralee Munshi2, Amita Dubey3, Ram Gupta1, Rosa Anna Busiello4, Antonia Lanni5, Fernando Goglia6, Ramesh C Gupta7, Vijay Chauthaiwale8, Chaitanya Dutt91Pharmacology, 2Cellular and Molecular Biology, 3Pre-clinical and Safety Eva
Externí odkaz:
https://doaj.org/article/e84565ddb2e642eea6cb0aa11386a7cd
Autor:
Ramesh Chandra Gupta, Rosa Anna Busiello, Shitalkumar Zambad, Chaitanya Dutt, Pieter de Lange, Davinder Tuli, Rosalba Senese, Vijay Chauthaiwale, Fernando Goglia, Maria Moreno, Laxmikant Chhipa, Federica Cioffi, Elena Silvestri, Assunta Lombardi, Siralee Munshi, Antonia Lanni
Publikováno v:
The FASEB Journal. 24:3451-3461
Chronic overnutrition and modern life-styles are causing a worldwide epidemic of obesity and associated comorbidities, which is creating a demand to identify underlying biological mechanisms and to devise effective treatments. In rats receiving a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51004b25469455f1e071b7d7541af1c3
https://doi.org/10.1096/fj.10-157115
https://doi.org/10.1096/fj.10-157115
Autor:
Siralee Munshi, Shari L. Caplan, Jinsheng Liang, Jiaping Gao, Bethany A Dale, Ramesh Chandra Gupta, Gregory Raymond Bebernitz, Michael Kavana, Brian Edward Vash, Paul Taslimi, Richard Deacon, Louise Kirman, Sunil Sadanand Nadkarni, Melissa S. Grondine, Valerie Beaulieu, Mesut Kakmak, Wieslawa Maniara, Irene St. Denny, Alokesh Duttaroy, Herbert F. Schuster, Travis Stams
Publikováno v:
Journal of Medicinal Chemistry. 52:6142-6152
Type 2 diabetes is a polygenic disease which afflicts nearly 200 million people worldwide and is expected to increase to near epidemic levels over the next 10-15 years. Glucokinase (GK) activators are currently under investigation by a number of phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f42388d9d384fa55ff534be29a734c9
https://doi.org/10.1021/jm900839k
https://doi.org/10.1021/jm900839k
Autor:
Pundlik Shinde, Rajesh Sonawane, Shitalkumar Zambad, Rajendra Odedara, Jitendra Patel, Ramesh Chandra Gupta, Chaitanya Dutt, Sanjay Srivastava, Vijay Chauthaiwale, Siralee Munshi, Davinder Tuli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:949-953
Various spiro[chroman-2,4'-piperidin]-4-one derivatives (38a-m and 43a-j) have been designed, synthesized and evaluated for in vitro acetyl-CoA carboxylase (ACC) inhibitory activity. Several compounds have shown ACC inhibitory activity in low nanomol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389a71c751da806d7b1222c56f0eae4a
https://doi.org/10.1016/j.bmcl.2008.11.099
https://doi.org/10.1016/j.bmcl.2008.11.099
Autor:
Gregory R. Bebernitz, Valerie Beaulieu, Bethany A. Dale, Richard Deacon, Alokesh Duttaroy, Jiaping Gao, Melissa S. Grondine, Ramesh C. Gupta, Mesut Kakmak, Michael Kavana, Louise C. Kirman, Jinsheng Liang, Wieslawa M. Maniara, Siralee Munshi, Sunil S. Nadkarni, Herbert F. Schuster, Travis Stams, Irene St. Denny, Paul M. Taslimi, Brian Vash
Publikováno v:
Journal of Medicinal Chemistry; Oct2009, Vol. 52 Issue 19, p6142-6152, 11p