Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Siraj K. Zahr"'
Autor:
Adelaida Kolaj, Siraj K. Zahr, Beatrix S. Wang, Taylor Krawec, Hilal Kazan, Guang Yang, David R. Kaplan, Freda D. Miller
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112242- (2023)
Summary: Here, we ask how developing precursors maintain the balance between cell genesis for tissue growth and establishment of adult stem cell pools, focusing on postnatal forebrain neural precursor cells (NPCs). We show that these NPCs are transcr
Externí odkaz:
https://doaj.org/article/f7de2f910d1f4882bd97afbe9a72baf7
Autor:
Guang Yang, Gonzalo I. Cancino, Siraj K. Zahr, Axel Guskjolen, Anastassia Voronova, Denis Gallagher, Paul W. Frankland, David R. Kaplan, Freda D. Miller
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1022-1036 (2016)
Maternal diabetes is known to adversely influence brain development in offspring. Here, we provide evidence that this involves the circulating metabolite methylglyoxal, which is increased in diabetes, and its detoxifying enzyme, glyoxalase 1 (Glo1),
Externí odkaz:
https://doaj.org/article/7a23eaa5baf6414cb5912d376c6df4dc
Autor:
Reshma Amin, Nikolaus E. Wolter, Evan J. Propst, Siraj K. Zahr, Suhail Al-Saleh, Jackie Chiang, Indra Narang, Justin Cottrell
Publikováno v:
International journal of pediatric otorhinolaryngology. 138
Adenotonsillectomy (AT) is common in children with trisomy 21 but outcomes are variable. Therefore, practitioners must have accurate information regarding the risks of the procedure specific to trisomy 21 to help patients weigh the risks and benefits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76da2c6ba3d9461a675134da94590fcb
https://pubmed.ncbi.nlm.nih.gov/33152968
https://pubmed.ncbi.nlm.nih.gov/33152968
Autor:
Robert A. Civitarese, Norman D. Rosenblum, Sara Mirali, Tina Binesh Marvasti, Ayesh K. Seneviratne, Sachin Doshi, Siraj K. Zahr
Publikováno v:
Clinical and Investigative Medicine. 42:E14-E16
Translational research (TR) is a multidirectional and multidisciplinary integration of basic research, patient-oriented research and population-based research, with the long-term goal of improving human health. Unfortunately, the current scientific t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c21c568dcd4cd2e518e05dd1cd693308
https://doi.org/10.25011/cim.v42i3.33088
https://doi.org/10.25011/cim.v42i3.33088
Publikováno v:
Cell Death Differ
The mammalian neocortex underlies our perception of sensory information, performance of motor activities, and higher-order cognition. During mammalian embryogenesis, radial glial precursor cells sequentially give rise to diverse populations of excita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a6defda27a811c64d0ac38d754a622
https://pubmed.ncbi.nlm.nih.gov/31551564
https://pubmed.ncbi.nlm.nih.gov/31551564
Autor:
Paul W. Frankland, Guang Yang, Denis Gallagher, Axel Guskjolen, Siraj K. Zahr, David R. Kaplan, Anastassia Voronova, Freda D. Miller, Gonzalo I. Cancino
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1022-1036 (2016)
SummaryMaternal diabetes is known to adversely influence brain development in offspring. Here, we provide evidence that this involves the circulating metabolite methylglyoxal, which is increased in diabetes, and its detoxifying enzyme, glyoxalase 1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cdd56f17ce77d93aa083ea623bba4e
Autor:
Scott A. Yuzwa, David R. Kaplan, Siraj K. Zahr, Michael J. Borrett, Geoff Clarke, Guang Yang, Freda D. Miller, Peter W. Zandstra, Gonzalo I. Cancino
Publikováno v:
Neuron. 91:988-1004
The neural stem cell decision to self-renew or differentiate is tightly regulated by its microenvironment. Here, we have asked about this microenvironment, focusing on growth factors in the embryonic cortex at a time when it is largely comprised of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27381dce38e4eddada40450d4ea2d8a
https://doi.org/10.1016/j.neuron.2016.07.037
https://doi.org/10.1016/j.neuron.2016.07.037
Autor:
Michael J. Borrett, Anastassia Voronova, David R. Kaplan, Guang Yang, Freda D. Miller, Siraj K. Zahr, Scott A. Yuzwa, Hilal Kazan
Publikováno v:
Neuron. 97(3)
Summary The mechanisms instructing genesis of neuronal subtypes from mammalian neural precursors are not well understood. To address this issue, we have characterized the transcriptional landscape of radial glial precursors (RPs) in the embryonic mur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1003aadfeed7be9c057816851194ccb1
https://pubmed.ncbi.nlm.nih.gov/29395907
https://pubmed.ncbi.nlm.nih.gov/29395907
Autor:
Jing Wang, Beatrix S. Wang, Freda D. Miller, Anastassia Voronova, Scott A. Yuzwa, Siraj K. Zahr, Charvi Syal, David R. Kaplan
Publikováno v:
Neuron. 94:500-516.e9
During development, newborn interneurons migrate throughout the embryonic brain. Here, we provide evidence that these interneurons act in a paracrine fashion to regulate developmental oligodendrocyte formation. Specifically, we show that medial gangl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d505ab8ed5765744874e8cce1d97f3
https://doi.org/10.1016/j.neuron.2017.04.018
https://doi.org/10.1016/j.neuron.2017.04.018