A generic anti-drug antibody assay for monoclonal antibody therapeutics with broad dynamic range eliminates the need for titer evaluation in preclinical studies

Autor: Li, Hao, Foley, Alejandro R., Shim, Jeongsup, Siradze, Ketevan, Webb-Vargas, Yenny, Sperinde, Gizette, Fischer, Saloumeh K.

Publikováno v: In Journal of Pharmaceutical and Biomedical Analysis 15 October 2024 249

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Relation of Increased Prebeta-1 High-Density Lipoprotein Levels to Risk of Coronary Heart Disease

Autor: Guey, Lin T., Pullinger, Clive R., Ishida, Brian Y., O'Connor, Patricia M., Zellner, Christian, Francone, Omar L., Laramie, Jason M., Naya-Vigne, Josefina M., Siradze, Ketevan A., Deedwania, Prakash, Redberg, Rita F., Frost, Philip H., Seymour, Albert B., Kane, John P., Malloy, Mary J.

Publikováno v: In The American Journal of Cardiology 2011 108(3):360-366

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Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A.

Autor: Peng K; Department of BioAnalytical Sciences, Genentech Inc, 1 DNA Way, South San Francisco, California, 94080, USA. peng.kun@gene.com., Wang Y; Department of Clinical Pharmacology, Genentech Inc, South San Francisco, California, USA., Siradze K; Department of BioAnalytical Sciences, Genentech Inc, 1 DNA Way, South San Francisco, California, 94080, USA., Erickson R; Department of BioAnalytical Sciences, Genentech Inc, 1 DNA Way, South San Francisco, California, 94080, USA., Fischer SK; Department of BioAnalytical Sciences, Genentech Inc, 1 DNA Way, South San Francisco, California, 94080, USA., Staton TL; Department of OMNI Biomarker Development, Genentech Inc, South San Francisco, California, USA.

Publikováno v: The AAPS journal [AAPS J] 2018 Dec 13; Vol. 21 (1), pp. 9. Date of Electronic Publication: 2018 Dec 13.